Samantha finds out about an endangered butterfly habitat and needs to stop her boss and the firm's construction project that would kill them. She decides to use Dena, who is clueless about Sam's plan, to go out with her boss and persuade him to stop the construction project. After Todd and Sam's passionate kiss, Sam is feeling ignored by him.

Sam is going to Todd's photo exhibit, but doesn't want to go alone, so she asks Craig, whom she thinks is a complete stranger, to join her. Sam soon gets the hint that they've met before and things doing go smoothly. Kevin discovers a demeaning picture of Sam in Todd's photo collection.

The guy that Andrea has a thing for, asks Samantha to marry him. He also turns out to be the wealthy owner of the real estate firm that they both work at. Samantha worries that it may harm their friendship more than anything else.

Sam gets her father's car into an accident and pushes it into a lake, making him think it was stolen. He feels so bad for her that he ends up buying her a new car. Regina discovers clues about the accident and uses that as blackmail to force Sam to model at a party.

Samantha is suspicious about Regina's action, which lead her to believe she is having an affair. But she's not alone. Todd is cheating on Chloe, who is none the wiser, with Samantha. Dena and Regina are contemplating opening up their own coffee shop.

When Sam feels her biological clock ticking away and realizes her desire to be a mother, she tries to probe her own motherly instincts by borrowing Dena's dog to find out if she's nurturing enough to care for and love it. Meanwhile, Regina attempts pilot lessons when she learns that Howard's late step-brother has willed them a plane, and Andrea continues to fuel the tabloid fires while she dates famous pro-basketball star Tony Dane.

In the season finale, Samantha is beginning to think that Chloe is using the sympathy card by saying her aunt is sick, just so Todd won't break up with her like he promised Samantha. Andrea and Regina are having several disagreements over how to plan Samantha's birthday party.

It's Samantha's first day back to work and her first board meeting gives her a shocking look at just how cutthroat and competitive she really was.

As a last ditch effort to try and regain some of her lost memory, Sam seeks professional help from a hypnotherapist, but doesn't get the help she expected. Sam hears a bombshell confession from Todd.

Sam tries to make herself appear to be an environmentalist, so Owen might like her more. Andrea doesn't fare well when the basketball player, Tony Dane, is looking for a date.

Sam finds out she was a dancer before she contracted amnesia, which prompts her to join her mother in the fight against her mother's nemesis in the annual dance contest at the country club. Meanwhile, Todd drags his feet in vacating Sam's place because of his financial ability to secure a new place of his own.

Samantha vaguely remembers something about Winston Funk's ex wife Gigi before the accident. Chapman tries to ask Dena to marry him. Andrea tries to lure Tony Dane into bed. Regina is caught in a love triangle as she prepares to leave on vacation with Howard.

Sam discovers that a family heirloom is the reason why her mom was in a feud with her sister and a mother, that Sam didn't know she had. Andrea is viewed as a jinx to Tony's team, after they start losing when she is there.

Sam becomes the head of the charity foundation for Winston Funk and hires Andrea as her vice president of legal affairs. She soon regrets this idea when Andrea shirks her duties in favor of planning her wedding.

Thinking she already ruined one job for him, Sam tries to secretly help Todd out by distracting the competition up for the same job as Todd. Unbeknownst to Dena, Regina tries to sell Dena's house, so that she can still work with Sam.

After the breakup between Owen and Sam, The Newlys, Dena, and Andrea decide to pack it up and head out for an overdue family vacation to a lodge. Sam is met by an unexpected friend at the lodge, Brad, who was her childhood sweetheart. Things get turbulent when Andrea makes a pass at him.

Sam thinks she's in love with Kevin and steps things up a bit, but it may prove to be more than Kevin can handle.

Sam dates a rock star to whom Dena and Andrea take a liking. Their unruly behavior toward Sam's new beau causes Sam to inch farther and farther away from her friends.

Sam decides to give Todd a second chance by going out with him on another "first date," but Todd doesn't trust Winston Funk, believing he and Sam may continue the affair they were having before the accident. Meanwhile, Andrea appears on a reality TV series about celebrity weddings, along with her gay basketball star Tony Dane.

Since Samantha has no memories of the past, including her sexual experiences, she is faced with the decision of waiting this time for the right guy to come along, or to experiment.

Desperate to regain her memory, Sam opts to join a clinical trial and starts taking pills for her memory. Sam's memories start coming back, but she doesn't like what she learns about her former self. Elsewhere, someone confuses Dena and Andrea as being a gay couple, which frustrates Andrea and sends her on the hunt to find someone hotter than Dena.

Regina sets Samantha up on a blind date with the man who is refinishing her floors. She turns to Todd for advice when she leads the guy to think she is an avid hockey fan.