The Cooper family grapples with the death of George Cooper Sr.

Sheldon leaves East Texas for the California Institute of Technology following the death of his father.

Sheldon invites the entire school to a party for the Nobel Prize announcements. Also, Connie learns more about Dr. Sturgis' past, and Georgie's desire for cable TV leads to a standoff between him and George Sr.

George Sr. gets an exciting job offer, and Sheldon prepares for his move to California.

Sheldon and Mary head to Germany while the rest of the Cooper family braves a tornado that is heading straight for Medford.

Sheldon discovers that Mary's been keeping a secret about his future. Also, Connie is furious when she learns Dale fired Georgie.

A video game takes over Sheldon and Connie’s life. George Sr. is jealous when Georgie bonds with Herschel at the auto shop.

Georgie is thrilled when Veronica stays at the Coopers' house for a few days. Also, Connie and Dr. Sturgis celebrate their one-year anniversary.

After graduating high school, Sheldon has a breakdown when he realizes he may not be ready for college. Dale tries to make amends with Connie.

When Mary’s faith is shaken by a tragedy in the community, Sheldon becomes an unlikely ally.

When a NASA representative visits Sheldon’s school and dismisses his science, Sheldon is set on a mission to prove him wrong.

Sheldon attempts to build a nuclear reactor. Also, a university cocktail party gets heated when Dr. Sturgis’ colleague, Dr. Linkletter, flirts with Connie, and Georgie is heartbroken when he learns Veronica has a boyfriend.

Sheldon asks for a computer and unknowingly sparks a heated argument between Mary and George Sr. over the family’s finances.

When Connie is pursued by two gentlemen callers, Sheldon interferes, forcing her to set some ground rules.

When Mary takes a job as church secretary, she finds herself becoming Pastor Jeff's marriage counselor. Also, Sheldon and Missy spend their first afternoon home alone.

When Dr. Sturgis recommends Sheldon and Missy for a university research study on twins, Mary is unhappy when the test results go to Sheldon's head.

Sheldon makes a terrifying mathematical discovery while tutoring Billy. Also, Mary is jealous of Missy's relationship with Mandy and Connie.

The Coopers can't be found as Mandy goes into labor. Also, Sheldon is excited about the launch of his database.

George Sr. strikes a deal with Sheldon to tutor Georgie when poor grades threaten to keep him from playing football. While Sheldon's tutoring attempts are ultimately unsuccessful, he does learn some skills from his brother.

When Sheldon moves to Dallas to attend a school for gifted children, the family struggles to cope with his absence.

The kids brainstorm ways to resolve a family feud when Connie refuses to give George Sr. her brisket recipe.

Sheldon gets an odd request from an old friend, Paige. Also, George Sr. and Mary are caught in the middle of Connie and Dale's breakup, and Georgie comes clean to Mandy.

Sheldon starts an internet flame war, and Missy stands up to the boys on her baseball team. Also, Connie is unhappy when George Sr. spends time with her new boyfriend.

Sheldon visits CalTech for the very first time. Also, Georgie is furious when Mary listens in on a phone call with his girlfriend, and Connie tries to cheer up a jealous Missy.

A worried Mary sends Sheldon to Sunday school after she finds him playing Dungeons and Dragons with his friends, Tam and Billy.

Sheldon is forced to take a break from science when his new obsession with "The Lord of the Rings" leads to an unhealthy habit. Also, Missy asks George Sr. to teach her how to play catch.

After Dr. Sturgis experiences a nervous breakdown, Mary worries Sheldon is headed down a similar path. Also, Georgie discovers he has a knack for sales.

Missy's first heartbreak triggers a series of events that lead the Cooper family to the brink.

When flu season hits Medford, Sheldon takes extreme measures to remain healthy.

When their mothers force them to attend Vacation Bible School. Also, George is furious after Georgie makes a questionable purchase.

Sheldon's published paper leads to a frenzy of grad school recruiting, and Georgie tries to speak more properly in front of his daughter.

Sheldon studies his family for a psychology project. Thanksgiving dinner turns into a family fight when George Sr. is offered a job in Oklahoma.

When Sheldon is no longer academically challenged at Medford High, he audits a college class taught by Dr. John Sturgis.

George and Mary insist on meeting the new woman in Georgie's life. Also, Sheldon and Missy have suspicions about what's going on with their family.

News of the tornado reaches Sheldon and Mary in Germany. Also, with the Cooper house in chaos, Missy steps up.

While Sheldon is busy keeping tabs on Connie’s budding relationship with Dr. Sturgis, George Sr. and Mary attempt to bond with their other children.

Sheldon's search for a comic book leads him to a breakthrough. Also, Georgie and Mandy have an uncomfortable first encounter with her parents, Jim and Audrey.

When Sheldon has to spend a few days in the hospital, he turns into the world’s worst patient. Also, Missy gets a taste of what life would be like without her twin.

The Coopers help Pastor Jeff through a rough patch in his marriage. Also, Sheldon pressures church members for donations when Mary takes him to work for a day.

Sheldon takes his first engineering class with Professor Boucher. Also, Meemaw and Dale help take care of his ex-wife, June.

When Sheldon learns that people with stunted childhoods can turn into social outcasts, he tries to act. Connie and Dr. Sturgis' relationship is tested when she teaches him how to drive.

Sheldon experiments on Missy, and Georgie joins Mary’s bible study to spend more time with his crush, Veronica.

Sheldon campaigns to become Dr. Linkletter's lab assistant. Also, Georgie enlists the help of Mr. Lundy, the drama teacher, for a surprising business venture.

Connie's gambling room is a success, and Sheldon dips his toe in the stock market. Also, Missy starts a business.

Sheldon butts heads with Dr. Lee, a new scientist in the lab. Also, Mary is given a lotto ticket.

Sheldon attends his first comic book convention; Mary tries selling makeup.

Sheldon joins Dr. Linkletter and Dr. Sturgis on a science road trip. Also, Georgie continues to lie about his age.

Sheldon wants to search for life on other planets and Mandy answers Georgie's marriage proposal. Also, Missy is caught between two friends.

Sheldon's database invention puts him at odds with the university. Also, the church takes issue with Connie's video store.

Dr. Linkletter pushes Sheldon to make friends with his fellow students at college. Also, Georgie gets a pager.

9-year-old Sheldon Cooper is a once-in-a-generation mind capable of advanced mathematics and science but learns that isn’t always helpful growing up in East Texas, a land where church and football are king.

At college, Sheldon decides to expand his responsibilities and become a dorm resident advisor. Also, Connie and Dale make a sketchy business deal, and Mary and George Sr. rekindle their romance.

Sheldon battles President Hagemeyer's mysterious boss over the university's science requirements. Also, Mary discovers that Georgie is working at Connie's illegal gambling room.

Sheldon acts as Mary's spy during a youth lock-in at church. Also, Georgie is attracted to an older woman, Mandy.

Sheldon gets the science yips and has to learn how to not think. Also, George Sr. plays handyman at Brenda Sparks' house.

Mandy gets an exciting job opportunity and Sheldon worries that he's falling behind. Also, Georgie takes his daughter to work.

Sheldon and Missy try to help the family’s finances. Also, Mary struggles to find her footing without the church.

George Sr. is worried that Mary wants another baby and gets a vasectomy behind her back. Meanwhile, Drs. Linkletter and Sturgis go to Sheldon for science tutoring.

Dale and Connie work out relationship issues while playing Dungeons and Dragons with Sheldon and Missy. Also, Mary and George take a trip with Coach Wilkins and his wife, and Georgie freaks out when his girlfriend thinks she's pregnant.

Sheldon refuses to ride in a car after getting into an accident with Connie. Also, Missy uses their trauma to her advantage at school and Connie is forced to take the church shuttle while her car is in the shop.

Sheldon gets a dorm room all to himself. Also, Connie gains an unwanted business partner.

Sheldon makes friends with his dorm neighbors; George Sr. learns his job is in jeopardy.

After being released from the mental hospital, Dr. Sturgis unexpectedly breaks up with Connie.

Connie takes matters into her own hands when Sheldon's philosophy teacher, Professor Ericson, sends him into a tailspin. Also, George Sr. learns Georgie has been cutting class.

Missy steps up, Mary has a surprise for George, and Sheldon finds his dorm occupied.

Connie gets assigned a tough probation officer, and Georgie takes marriage advice from his father-in-law.

Sheldon, Missy and Georgie adapt to new living arrangements. Also, Connie opens a gambling room.

Connie meets Dale’s ex-wife, June. Sheldon is forced to work on a group project with reluctant college students.

Sheldon uses his new friendship with the school bully to boss Georgie around. Also, Missy steals Connie's makeup for picture day.

When George Sr. accidentally lands the school librarian in the hospital, the Cooper family must nurse her back to health. Connie gives Georgie relationship advice.

Sheldon takes matters into his own hands when Connie refuses to drive him to a lecture with Dr. Linkletter. Also, Georgie tries to impress Veronica with his new business venture

Sheldon, Dr. Linkletter and Connie team up on a science experiment. Also, Mary is jealous that Pastor Jeff and Brenda are spending time together, and Georgie has a new side hustle.

Sheldon helps his roommate try to beat the stock market, Missy and Billy Sparks throw a party, and Mary finds a new church.

Sheldon realizes he is the weakest student in his class; Meemaw is looking to expand her gambling business.

To appease his worried mother, Sheldon employs the techniques of a self-help book to try and make a friend.

Sheldon fakes being sick to avoid a swim test at school. Also, Dr. Sturgis spies on Connie's new boyfriend.

Sheldon and George Sr. dine with President Hagemeyer and a university benefactor. Also, Georgie gives Missy some brotherly advice when Mary won't let her go to the school dance, and Dale and June convince Connie to attend their son's wedding.

Missy asks some uncomfortable questions at church, and Connie and Georgie go into business together.

Sheldon considers dropping out of college to focus on building his database. Also, George Sr. is frustrated when someone else gets credit for his football wins.

Sheldon encourages Missy to question the Bible. Also, Connie is determined to catch George Sr. in a lie, and Mary helps Pastor Jeff search for a youth pastor.

Sheldon learns the university is building a database without him. Also, Mary takes care of a bedridden Mandy and Meemaw.

Mary struggles to make new friends while Mandy pushes Georgie to date another woman.

Sheldon copes with the death of a hero. Also, Missy wants to babysit, and Georgie struggles with his big secret.

Sheldon struggles to cope with the first signs of puberty. Also, Mary and George Sr. hunt for new jobs, and Georgie and Meemaw take a business trip across the border.