After Jubal narrowly escapes a calculated assault on a secret FBI office, the team discovers a rogue terrorist group has infiltrated the FBI. Unsure of who to trust, the team must work in the shadows to unmask the culprits threatening the sanctity of the New York field office.

When a CEO is killed by a targeted explosion inside his penthouse, the team must work to figure out how someone accessed the highly secure building. Their task is further complicated when they discover the crime may be the work of an artificial intelligence program. Meanwhile, Maggie pumps the brakes on her personal life.

A woman with information about the death of Maggie’s husband is abducted, leading OA and the team to uncover a criminal operation larger than anyone imagined. Also, Dana puts her career in jeopardy when she stands by and allows Maggie to work on this case that has such a personal connection to her.

When a passenger train is hijacked and rerouted while at high speed with an unarmed OA and Gemma on board, the team races to wrest control away from the unhinged perpetrators and prevent a catastrophe.

The investigation into an assistant U.S. attorney’s death leads the team to a related airline whistleblower scandal and the chilling discovery that they don’t have much time to thwart terrorists from crashing numerous in-flight commercial airplanes. Dealing with the memory of his brother, who was a 9/11 victim, the case pushes Scola hard to prevent another catastrophe.

When five prominent men are killed at a trendy New York City restaurant, the team’s investigation brings them into contact with a lieutenant in Antonio Vargas’ cartel, triggering a long-awaited showdown between Isobel and Vargas.

After the police ignore a desperate father's plea for help, he abducts a billionaire's daughter and holds her hostage in a near-impenetrable safe room until his own missing child is returned to him. Also, Jubal puts his hostage negotiation skills to the test.

The FBI team investigates a drug deal gone bad after the body of a college student is found. Also, Detective Hailey Upton temporarily joins the team and finds her usual investigative methods clash with the Bureau's more buttoned-up environment.

Jubal's longtime confidential informant brings intel of an impending large-scale terror attack to the team, but when the details don't add up, Jubal must sift out the truth from a man who's known him at his worst.

Jess LaCroix and his team come to help OA find a fugitive LaCroix arrested years ago after a bus with 26 students goes missing and he's the main suspect. The crossover continues on FBI: Most Wanted S01E09 Reveille (II).

When a prominent doctor is found dead in a ritualistic slaying, the team must race against time to hunt down a religiously motivated serial killer. Also, Scola faces a life-or-death decision.

The murder of a TSA agent leads the team to hunt down a killer who is using drug mules to exploit airport security checkpoints. Also, OA struggles to cope with the aftermath of the sarin gas exposure and the 10th anniversary of his army friend's death in Afghanistan.

After a young woman is killed on her way home from a lavish yacht party, the team investigates who she was and how she came to be at the event, which was attended by some of the most influential people in the world. Also, Maggie brings Crosby into the investigation after a murder suspect is identified as a veteran who had been on several Army operations with Crosby. The crossover continues on FBI: Most Wanted S03E01 Exposed (II) and FBI: International S01E01 Pilot (III).

OA is forced to confront one of his biggest fears when the team discovers that deadly sarin gas may have been sold to terrorists.

The son of a retired FBI agent is kidnapped, and the team must investigate if it's an act of revenge; Isobel must make a hard call when information from the past comes to light.

After a truck filled with armour-piercing rifles is hijacked, the team works to discover who stole it, and what they have planned for the stolen weapons. A friend from OA's past returns to help with the case, but OA isn't sure he can trust him.

As the team works to rescue a 5-year-old kidnapping victim, Scola suspects the boy’s mother isn’t being forthcoming about why her son was targeted. Also, Nina struggles to open up to Scola about matters in their relationship.

After two jurors for a high-profile mafia trial are gunned down, the team jumps into an organized crime investigation until it is discovered that the jurors may not have been the intended targets at all. The case becomes personal for Scola when he learns that one of his former drill instructors from the military academy he attended may be linked.

As Maggie and the team search for New York's latest serial killer, the copycat method used by the murderer forces Maggie to seek help from Ray Distefano, the serial slasher she put behind bars.

As the team investigates a deadly robbery that garnered a cache of automatic weapons for the killers, they discover one of the perps is a classmate of Jubal’s son, who is reluctant to cooperate with the case.

When the leader of a drug cartel and one of the world's most wanted men, Antonio Vargas, is apprehended by the team, the entire FBI headquarters is put at risk when his henchmen unveil a terroristic threat to free him. During the turmoil, Isobel must make the difficult decision whether to sacrifice her conscience or her career.

The team jumps into action when analyst Kelly Moran is taken hostage.

The team investigates a series of brutal assaults; OA hides information about his own mugging.

After Rina is critically wounded while heading to work with Jubal, the team makes the chilling discovery that a vengeful Vargas orchestrated the shooting from behind bars and continues to target the rest of their team and their loved ones.

The team races to stop an active serial killer after three women are found weighted down at the bottom of a lake, and Jubal looks into an old closed case after there are multiple similarities to the recent victims.

To aid Scola in his undercover mission to find the terrorists believed to be behind the imminent attack in New York City, Maggie calls in Remy, whose well-connected informant from a prior case may be key to moving the operation forward. The crossover starts on FBI: International S02E16 Imminent Threat (I). It continues on FBI: Most Wanted S04E16 Imminent Threat (III).

When the team’s sex trafficking sting operation goes sideways, they race to recover a human trafficking victim. Meanwhile, Maggie makes a connection with a 911 operator to help find the girl before she is whisked out of the city or worse.

After a young girl goes missing in Queens, the team discovers the kidnappers used her as leverage to carry out a major explosives heist, sending them on a hunt for the dangerous culprits. Meanwhile, Scola and Dani begin working on their footing as partners.

The Somalian terrorist group behind the death of Agent Hobbs resurfaces, sending the team on a chase to take them down for good.

Maggie, OA and the team must stop a hacker who is disabling life-saving equipment in several New York City hospitals. Jubal's son waits for important surgery at one of the impacted hospitals.

When a morning show host is murdered inside her home, the team tracks the killer, who they realize is targeting powerful women. Also, things become awkward for Scola when Special Agent Nina Chase becomes part of the team during Maggie's recovery.

After a series of targeted bombings in Queens, the team fears a citywide gang war is imminent – until a tip from OA's old Army buddy, Clay, directs their attention to an unexpected and powerful foe. Meanwhile, Scola continues to struggle to find a new partner.

When a famous rapper and two teen fans are gunned down on his tour bus, the team discovers there may be more to the story than his feud with another rapper. Meanwhile, Isobel hits a major milestone that has her contemplating her future at the Bureau.

The team must track down two assailants who wear animal masks while committing armed robberies, with the latest leaving an off-duty 26 Fed security guard dead. Also, Tiffany and Scola butt heads on whether or not to accept the local NYPD’s offer to help in the investigation.

Maggie returns from medical leave in time to help the team investigate two homicides: a law student on track to attend the FBI Academy and a young man with possible gang ties. Also, an inadvertent revelation from Maggie causes OA to worry that she is rushing back into the job too quickly.

The team welcomes a new member, Special Agent Tiffany Wallace, as they search for killers who orchestrated a mass shooting at a media company, and OA’s personal connection with the case threatens to cloud his judgement.

A loving husband and father of two, Jim Russo, is kidnapped after accidentally getting involved in illegal dealings far beyond what he imagined. Also, Jubal must make a difficult decision regarding his family and their future.

After an altercation with a student, a teacher goes missing, leading the team to investigate everyone who might have had a grudge against him. Also, a key witness in the case steps up to help, and Maggie does whatever she can to ensure their safety.

The team rushes to track down two doctors abducted by a desperate father willing to do anything to save his son. Also, Jubal's uncertainty in his family life affects his judgement during the hostage situation.

When the daughter of a wealthy family is kidnapped in an attempt to gain notorious internet fame, Maggie and OA discover the kidnapper’s plans go far beyond abduction in order to never be forgotten.

When the sister of Sydney Ortiz is the victim of an attempted kidnapping and sexual assault, Sydney seeks help from Isobel and the team in tracking down a meticulous serial offender who leaves no evidence behind.

After a bomb explosion devastates a residential apartment building, special agents Maggie Bell and Omar Adom “OA” Zidan of the New York office of the Federal Bureau of Investigation investigate a possible war between rival gangs – that is, until their prime suspects are discovered brutally murdered.

As the team hunts a killer who is fatally shooting seemingly unrelated targets, an experience on the job has new agent Tiffany Wallace examining the tension between her career as an FBI special agent and the responsibility she feels to her community as a Black woman.

After a park ranger is shot dead by a masked assailant on Governors Island, the team discovers a string of connected crimes that leads them to their toughest roadblock yet: an online conspiracy theory community.

After an employee of the U.S. Army is shot in an industrial park, the team works to track down the killer who reveals a larger plot at play. Meanwhile, Tiffany continues to struggle with the guilt surrounding Hobbs' death.

When a retired DEA agent is shot outside a bakery, the team works to determine if the victim’s past cases or current bouncer job are connected to the murder. Also, Nina and Tiffany clash over the use of an informant while they are paired during the investigation.

Special Agents Maggie Bell and OA Zidan rush to track down an active sniper with an elusive motive as the body count continues to rise.

When an off-duty diplomatic security agent is fatally shot in New York City trying to apprehend someone, the team investigates if there's a connection to his time working in Croatia.

The team investigates the murder of a professional informant after he's found dead outside an abandoned factory in Red Hook. Also, Maggie reconnects with an old colleague and mentor.

The team investigates an extremist gun group after an anti-gun lobbyist building is bombed; SAC Bashar dangles a possible promotion for OA.

When a federal judge is gunned down execution-style in broad daylight, the team is sent looking for a suspect with ties to a local Islamic center. Also, Maggie reunites with a former colleague while things become tense between OA and his girlfriend Gemma.

When a truck driver is murdered and the drug he was transporting goes missing, the team hunts for those behind the remaining batch that is already wreaking havoc on the streets of New York.

After a bomb leaves three people dead, the team presses a reluctant informant to gather information from his close friends who are under suspicion. Also, OA finds tension in his relationship with his girlfriend, Mona, when they clash on where the informant’s rights lie.

When a Muslim college student and his younger brother are murdered, the team connects with the outraged imam of OA's former mosque, who insists the victims were wrongly targeted as terrorists.

When an alt-right provocateur is murdered after giving a speech at a university in New York City, Maggie and OA investigate the school's more extreme political groups and rely on OA's sister, Amira, a student, for help.

When a judge and her daughter are murdered after she sentenced a man to life in prison, Maggie and OA search for the killer behind a possible retaliation. Dana has a vested interest in this case as she has a history with the victim.

When a wealthy accountant is gunned down for secretly testifying against a notorious drug lord, the team’s investigation leads Tiffany to ask for help from a friend who was formerly with the NYPD and is related to the dangerous crime boss.

When a chaotic campus protest turns deadly, the team is called in to help quell the mayhem and track down the murderer. Meanwhile, Jubal is concerned when Tyler is detained along with a group of student protestors.

After an immigration agent is fatally shot at a hockey game, the team attempts to find the shooter, who they believe may also be targeting Congressman Curtis Grange, who was at the same game.

After finding a group of teens dead from a drug overdose, the team races to find the dangerous dealer and his supplier. Meanwhile, OA questions where he stands in his faith.

The shooting of a federal corrections officer leads the team to an ex-Marine who has gone rogue ever since he returned from Afghanistan; Tiffany's sister looks to her for guidance when their younger brother begins to lash out.

After eight people are fatally poisoned at a deli in New York City, special agents Maggie Bell and OA Zidan trace the crime to an unlikely culprit and conduct a sting operation to prevent further attacks.

Special Agents Maggie Bell and OA Zidan investigate the death of a safety inspector and its possible connection to a leak at a nuclear power plant.

Maggie and OA lead the search for an abducted former biological weapons chemist.

When a local club owner is found dead, the team works quickly to find the motive behind the murder of a seemingly innocent man. Meanwhile, OA is smitten with a new love interest but is concerned that she's mixed up with the wrong crowd.

After a front-running female presidential candidate, Valerie Caldwell, is targeted with a car bomb, OA and Maggie must hurry to track down the bomber before they strike again. The case leads them to wonder whether this person is targeting Caldwell for her political aspirations or something else.

As the team investigates a string of jewellery store robberies that culminate in a double murder, they uncover a connection to a 16-year-old boy trying to survive the foster care system. Tiffany becomes personally invested after learning about the boy's ill-fated upbringing.

After a bomb detonates at a restaurant in Queens, the case becomes personal for OA, who grew up eating there. But what initially seems like a terrorist attack reveals itself to be more complex, and OA goes undercover to prevent another incident.

The team pivots when their sting operation to secure a massive bomb from an illegal broker leads them to discover that the device is already in the wrong hands. Also, Jubal’s promise to be present at his son’s birthday party is put to the test as the case continues to heat up.

When the director of a Brooklyn migrant center is abducted and held hostage along with his wife, the team must work quickly to meet the demands of their kidnapper. Also, Maggie picks Jessica's brain about motherhood.

When a board member of a soon-to-be-public medical tech company is murdered, the team tries to find out who had the most to gain from his death. OA is conflicted when pressure to help a family member is at odds with his commitment to tell the truth.

All eyes are on the team when they try to find out who kidnapped the only child of a prominent U.S senator. The abduction also uncovers a potential link to a similar case that was pushed to the side by local authorities.

The team is on the case when a suburban couple is murdered and all forensic evidence points to the home's previous owner, who is currently serving 10 years in federal prison.

The team realizes they have a cross-country serial killer on their hands; the case has ties to Isobel's father, Robert, and his hotel, leading to revelations about their fractured relationship.

Maggie and OA hunt down a ruthless group of robbers who are posing as police officers to target armored trucks.

A drug dealer is shot in a federal park and the team sets out to look for his killer; Maggie's sister returns to New York and complicates the case.

Maggie goes under cover working in a bar to investigate an anti-government group that regularly gathers there; a single father on the periphery of the group begins to fear he's in danger of becoming collateral damage.

After a key witness and a U.S. marshal are ambushed and killed, Maggie and OA must track down a man who leaked the information that led to their murders.

After multiple people are targeted and killed with a poisonous gas in broad daylight, the team races to find the killer, who they believe is tied to an eco-terrorist plot. Meanwhile, Maggie continues to explore motherhood.

A serial bomber appears to be targeting Wall Street’s elite. Maggie and OA search for a suspect who seems dead-set on revenge, while Dana deals with Spencer Briggs, a cocky profiler brought in to consult on the case.

After a man is killed by an explosive package shipped to his home, the team attempts to capture the sender and intercept his latest deadly parcel. Also, Maggie tries to trust her younger sister, Erin, is truly staying out of trouble as a new college student in NYC.

The team searches for an abducted college coed; Jubal has a tense encounter with Rina's mother.