The father of Laura’s daughter arrives in Gubbio. The young man’s parents demand custody of their grandchild at all costs. Laura and Don Matteo are at odds, but soon after the priest falls victim to deceit and is accused of harassment and even murder.

Sonia, a poor teenage mother, has managed to start a new life by creating a booming business selling children’s wear and by helping other women going through hard times. The man she is about to marry, however, is under questioning for the murder of a maid who is also discovered to be a prostitute.

The manager of a country hotel is found dead. By chance, Don Matteo discovers that the victim blackmailed unsuspecting hotel guests with video recordings. Suspicion falls on a woman who seems to be involved. Her husband accuses himself.

A laborer is found dead in the cement factory he works in. The suspect is the factory’s supervisor, who had differences with the victim. During research, Don Matteo and the police accidentally uncover a dramatic relationship.

A young woman is killed in her home. Natalina, the house keeper, can aid police investigations because she saw Giovanni Antonelli escaping from the house. The man admits that he had a relationship with the victim but refuses to confess to the crime. Police investigations move to a company, owned by the victim's 'real' boyfriend.

The town's volleyball team won the championship. During the celebration, Varoli, president and trainer of the team, is found dead. Vivana an ex-player of the team is suspected to have committed this crime because she has a motive: Since a car accident caused by Varoli, she is bound to a wheel chair. Don Matteo knows the girl and tries to prove her innocence.

A fire threatens the town. The culprit seems to be a little boy, Fabio, who immediately admits to be guilty. His father is convinced of his innocence and asks Don Matteo for help. It seems that the boy wanted to get his father's attention.

During a walk in the woods, Nerino falls into a 'hole' and discovers an old Etruscan tomb, filled with treasures. When police officers arrive, the treasures have disappeared. Suspicion falls on Lanza, a surly man who was involved in a robbery before. But Don Matteo suspects a certain Mr. Todi.

During a religious procession, Benito Lippi is bitten by a snake. Only an antidote can help to save his life, but it is hard to find since the snake is of a rare Asiatic breed. While police investigate who smuggled the snake into the country, suspicion falls on an oriental man who was seen near the victim during the procession.

Sergio is run over by a car. His fiancée Angela mourns his death but decides to begin a new life. After joining a music band, she receives anonymous threats: Someone wants her to leave town. Police investigations lead to a young man who seems to be involved in the car accident. Don Matteo has to solve the case.

Tarek, an immigrant, wants to traditionally arrange a wedding for his sons, who disagree with this tradition. To avoid the marriage, Mohammed commits a theft. When his brother Abdul gets involved in a violent crime, Don Matteo begins to investigate.

The stop mother of Assunta Cecchini’s best friend Valeria is found dead. The sergeant’s adolescent daughters idolize their reckless friend who, this time however, has really gotten herself into trouble.

In the series premiere, parish priest Don Matteo investigates a young man's apparent suicide.

The stables of an equestrian center catch fire. Suspicion falls on the old horse groom first, who has a motive to harm his employer. The employer, owner of the stables, might have a motive too - to collect insurance money. With Don Matteo's help and the aid of little boy Simone, the police uncovers the truth.

The young woman Petra (Jacqueline Lustig), on the run from police after supposedly committing a crime, takes Don Matteo hostage. While the police and Don Matteo's 'family' attempt to free him, our protagonist cooks up a plan: In order to escape and to uncover the truth, he tries to become an accomplice to his kidnapper.

The murder of a doctor is investigated.

Don Matteo's help is needed by a young woman, whose family is in financial distress and being blackmailed. The citizens, surprised about their priest's meetings with this beautiful woman, start to spread rumours.

Don Matteo investigates a drug ring that attacked an undercover police officer.

An inmate is killed in jail. Suspicion falls on a prisoner who claims to be not guilty, although his fingerprints were found on the murder weapon. A scorpion fight, organized by the citizens, points Don Matteo in the right direction.

Don Matteo is asked for help: Unfaithful wife Annalisa wants to save her marriage. Soon after this conversation she is found dead, her husband becomes main suspect. Don Matteo finds out that someone observed the victim.

Police officers find Don Matteo, gun in hand, next to a dead body. What happened? During a fight with the killer, the weapon was pushed in the priest's hands while the real murderer escaped. Imprisoned Don Matteo starts to investigate.

A well known entrepreneur is being blackmailed. Suspicion falls on a landlord who had differences with him before. While Don Matteo aids police investigations, the entrepreneur's son is poisoned...