In the season finale, Jackie returns to All Saints where she must confront everyone.

While Cruz is in care, Jackie goes over his head to get the ER under control, resulting in her dismissal from All Saints for insubordination. Jackie pulls Grace out of Catholic school. O'Hara goes into labour and Jackie returns to All Saints in spite of Cruz. Charlie arrives at the ER and Cruz asks Jackie to help him save Charlie's life.

Jackie has to confess that she used O'Hara's loan when her stash gets lost.

Coop gets a surprise. Jackie hits the road. Season finale.

Akalitus forgets to hire an escort for a psych patient who then lays waste to the pharmacy; Frank cancels a lunch date with Jackie; Zoey hears Coop and Carrie having sex; Jackie worries about Frank when she learns that a cop has been shot.

When HR demands urine samples from all the nurses, Jackie tries to avoid it as long as possible as well as her husband, who seems to have found out about her affair with Eddie.

Coop arranges a date for Georgia and Eddie while Jackie's daughter Grace starts therapy.

In order to get a phony prescription, Jackie falsifies an MRI. In the meantime the campaign's end has its effects on Coop and Eddie is back as the hospital's pharmacist.

Jackie runs out of drugs and Dr. Cooper decides to compete with Dr. O'Hara for the E.R. chief position.

Jackie covers for Cruz when he has a panic attack; Zoey surveys her coworkers for the best ways to conduct a breakup; Akalitus enlists the staff in an elaborate charade when her mentor is admitted with dementia.

O'Hara offers financial help, but Jackie and Kevin refuse to take it. Eddie and Kevin's secret friendship is revealed.

Jackie reluctantly attends Kevin's wedding. Carrie makes demands on Coop.

Jackie finds a new hiding place for her pills and buries the hatchet with O'Hara, who becomes ER chief; Zoey works her first double shift; Kevin invites Eddie to a backyard barbecue; Jackie must tell more lies to retrieve her misplaced stash.

After their custody meeting, Jackie rear-ends Kevin and wakes up as a patient in her own ER. Kevin accuses her of using. Coop begins covering for Carrie and taking on a lot more work. When Carrie checks on Jackie, she writes her a prescription for Oxy, unaware she's an addict. The most unlikely person asks Jackie out on a date.

Mrs. Akalitus is in a holy uproar as workers from the archdiocese remove her religious statues. Meanwhile, a new temp nurse makes his presence known in the ER, and some people don't appreciate it; Coop deals with personal, professional and podiatric problems; and Jackie tries to deal with Kevin playing matchmaker between Eddie and his sister.

Jackie's life gets a little more complicated because of a security guard and O'Hara's longtime affair comes to light.

In order to keep her secret credit card a secret, Jackie sets up a P.O. box for the credit card bills. In the meantime, Mrs. Akalitus offers Eddie to come back as the hospital's pharmacist.

Unhappy about Eddie and Kevin's friendship, Jackie asks Eddie to stop spending time with Kevin. A pharmaceutical company rep provides Jackie with drugs.

When Cruz learns about Jackie's rehab, he takes revenge on coworkers who have been covering up her drug problems. Meanwhile, Eddie is deposed by Kevin's lawyer; a dumped Lenny decides to take off for Europe; and Coop accompanies O'Hara to her ob-gyn appointment.

When a patient is suffering, Jackie supplies the patient with illegal marijuana to ease the pain. Meanwhile, Kevin prefers going out with Eddie rather than spend the night with Jackie and Zoey believes she is pregnant.

Kevin invites Jackie to a midnight rendezvous in order to give her a new wedding ring; the comatose movie critic wakes up but his tastes have radically changed.

Jackie and Frank have sex for the first time and he tells her he loves her. Akalitus has an extra spring in her step. Coop wants to take his mentoring of Carrie to the next level. Kevin and Grace show up at the hospital after Kevin finds a bag of pills in Grace's bag.

Things get out of control in the emergency room due to the recent firings and an overflow of patients who have been diverted from another hospital, causing Cruz to suffer a pulmonary episode and Jackie to step in. At home, a rebellious Grace refuses to go to class unless Jackie transfers her to public school.

Jackie is nervous about her date with Frank, so Zoey and Thor help her get ready and Eddie offers some friendly pointers. Prentiss misdiagnoses an injured dancer, but Akalitus and Coop catch his mistake before the patient leaves. Mike Cruz calls Jackie in a moment of need.

Jackie admits a patient she has treated before. As his condition worsens, Zoey questions whether Jackie did enough to help him on his previous visit. Jackie’s drug use starts to cause spontaneous nose bleeds.

An elderly patient checks in who has been treating his heart disease with chicken soup; Jackie discusses her daughter's anxiety with Dr. O'Hara; Eddie learns that he is to be replaced by a pill-dispensing machine.

Following HR's inquiry of the missing drugs, Mrs. Akalitus puts Jackie on probation. Meanwhile, Coop plans his wedding and Jackie's daughter Grace wants to be put on medication for her anxiety disorder.

Jackie gets inventive, setting her sights on returning to All Saints.

Longtime ER nurse Jackie Peyton bends the rules to bring some good from a patient's senseless death, while concealing her addiction to a pain killer she gets from her boyfriend, the hospital pharmacist.

Jackie's back to using again, but she's doing it differently this time: maintaining a clean and sober cover, going to 12-step meetings - even finding herself a sponsor - all the while getting her drugs from the towel girl at the gym. Meanwhile at All Saints, Zoey finds out that everyone knows about her 'secret' relationship with Prentiss. Season premiere.

A man is admitted with a steak knife sticking out of his chest. Eddie gives Jackie a Cartier bracelet for their one-year anniversary, but she rejects the gift. A baby is left in the nurses’ station and Akalitus takes the infant to her office.

Zoey finally confronts Jackie. Dr. Prince attracts a mob to All Saints.

Dr. Prince enlists Jackie's help with a patient. Thor reveals a secret.

Eddie tells Jackie that he now considers Kevin a real friend and can no longer lie to him; Jackie is remorseful when she learns that O'Hara is looking for a new employer; Akalitus announces that All Saints may get a visit from the First Lady.

Jackie stirs up trouble for the developers. Coop preps for his last day.

Jackie is ambushed by Antoinette. Coop's dream finally comes true.

Jackie is forced to perform a procedure on her own. Zoey learns a secret.

Still strapped for cash, Jackie's dealing takes a surprising turn.

Jackie and Kevin consider enrolling Grace in private school; the stoic Dr. O'Hara must endure the emotional thanks of a boy whose twin brother she saved; Zoey loses a patient for the first time.

Jackie's back at All Saints - but back to square one in a new role.

Jackie breaks several rules and regulations to help a 10-year-old girl caring for her lupus-stricken mother; Mrs. Akalitus accidentally tasers herself; O'Hara treats Zoey to a meal at a four-star restaurant.

Zoey leads the ER nurses on a walkout. Jackie battles her cravings.

Missing her family and adjusting poorly to single life, Jackie invites Kevin to meet her at a cafe but finds herself served with divorce papers instead of lunch; an attempted double suicide trauma case comes into the E.R.; Cruz institutes a draconian new dress code that is not a hit with his staff; Zoey looks for a new roommate and finds one in the lonely Jackie.

Jackie and Eddie make a purge their stash. Dr. Prince and Akalitus bond.

Jackie and her husband, Kevin, become concerned that their older daughter Grace is suffering from anxiety disorder; hospital administrator Mrs. Akalitus drinks Jackie's Percoset-laced coffee.

Jackie detoxes at home - with help. Frank raises an objection about Grace.

Jackie accuses Kelly of being inappropriate with two flirty high school girls; Coop begins to let go of childish things; Thor counsels Akalitus on her new phone system and some deeper matters; Jackie is unexpectedly delayed getting to Grace's pageant.

Picking up with her arrest, Jackie suffers through detox.