In the season finale, Jackie returns to All Saints where she must confront everyone.

While Cruz is in care, Jackie goes over his head to get the ER under control, resulting in her dismissal from All Saints for insubordination. Jackie pulls Grace out of Catholic school. O'Hara goes into labour and Jackie returns to All Saints in spite of Cruz. Charlie arrives at the ER and Cruz asks Jackie to help him save Charlie's life.

Coop gets a surprise. Jackie hits the road.

Jackie has to confess that she used O'Hara's loan when her stash gets lost.

Akalitus forgets to hire an escort for a psych patient who then lays waste to the pharmacy; Frank cancels a lunch date with Jackie; Zoey hears Coop and Carrie having sex; Jackie worries about Frank when she learns that a cop has been shot.

Jackie reluctantly attends Kevin's wedding. Carrie makes demands on Coop.

Jackie finds a new hiding place for her pills and buries the hatchet with O'Hara, who becomes ER chief; Zoey works her first double shift; Kevin invites Eddie to a backyard barbecue; Jackie must tell more lies to retrieve her misplaced stash.

When HR demands urine samples from all the nurses, Jackie tries to avoid it as long as possible as well as her husband, who seems to have found out about her affair with Eddie.

Mrs. Akalitus is in a holy uproar as workers from the archdiocese remove her religious statues. Meanwhile, a new temp nurse makes his presence known in the ER, and some people don't appreciate it; Coop deals with personal, professional and podiatric problems; and Jackie tries to deal with Kevin playing matchmaker between Eddie and his sister.

In order to get a phony prescription, Jackie falsifies an MRI. In the meantime the campaign's end has its effects on Coop and Eddie is back as the hospital's pharmacist.

A heavily medicated Jane Doe is brought into the ER and Jackie tasks Zoey with finding out who she is. Coop invites Carrie to dinner. Jackie faces conflict with both her daughters - Fiona has been acting out in class while Grace sneaks around the city with her older boyfriend.

Kevin interrupts Jackie and Frank's night. Akalitus' blood results are in and her memory loss is a result of a medication she's been taking. Zoey helps Prentiss organize his disaster of an office. Meanwhile, Jackie is convinced that Grace is sneaking behind her back to see Danny, but Grace assures her they broke up. Frank urges Jackie to work on her issues - so she attends an AA meeting.

Things get out of control in the emergency room due to the recent firings and an overflow of patients who have been diverted from another hospital, causing Cruz to suffer a pulmonary episode and Jackie to step in. At home, a rebellious Grace refuses to go to class unless Jackie transfers her to public school.

Jackie is caught off-guard when a nurse (Judith Ivey) she used to work with, who is dying of lung cancer, asks Jackie to help end her life. Meanwhile, Coop's mother (Blythe Danner) is admitted with a gall bladder attack. We learn that he is the only son of lesbians...a fact that delights Jackie and O'Hara.

After their custody meeting, Jackie rear-ends Kevin and wakes up as a patient in her own ER. Kevin accuses her of using. Coop begins covering for Carrie and taking on a lot more work. When Carrie checks on Jackie, she writes her a prescription for Oxy, unaware she's an addict. The most unlikely person asks Jackie out on a date.

Jackie covers for Cruz when he has a panic attack; Zoey surveys her coworkers for the best ways to conduct a breakup; Akalitus enlists the staff in an elaborate charade when her mentor is admitted with dementia.

Coop arranges a date for Georgia and Eddie while Jackie's daughter Grace starts therapy.

Jackie runs out of drugs and Dr. Cooper decides to compete with Dr. O'Hara for the E.R. chief position.

It's Jackie's one year anniversary of sobriety and she and Frank fight about their relationship. Zoey acts very professional and rigid around Prentiss after their intimate evening. Carrie's peer review does not go well. Grace has a breakdown about Jackie. Jackie takes something she shouldn't have.

Unhappy about Eddie and Kevin's friendship, Jackie asks Eddie to stop spending time with Kevin. A pharmaceutical company rep provides Jackie with drugs.

Jackie gets offered a job - and wants Zoey to come with her. Series finale.

Jackie's life gets a little more complicated because of a security guard and O'Hara's longtime affair comes to light.

Jackie is nervous about her date with Frank, so Zoey and Thor help her get ready and Eddie offers some friendly pointers. Prentiss misdiagnoses an injured dancer, but Akalitus and Coop catch his mistake before the patient leaves. Mike Cruz calls Jackie in a moment of need.

Victims of a bus accident are treated; two doctors join the rotation; O'Hara is happy spending time with her son; Akalitus gives Eddie his job back.

Jackie admits a patient she has treated before. As his condition worsens, Zoey questions whether Jackie did enough to help him on his previous visit. Jackie's drug use starts to cause spontaneous nose bleeds.

An elderly patient checks in who has been treating his heart disease with chicken soup; Jackie discusses her daughter's anxiety with Dr. O'Hara; Eddie learns that he is to be replaced by a pill-dispensing machine.

Following HR's inquiry of the missing drugs, Mrs. Akalitus puts Jackie on probation. Meanwhile, Coop plans his wedding and Jackie's daughter Grace wants to be put on medication for her anxiety disorder.

Dr. Prince enlists Jackie's help with a patient. Thor reveals a secret.

Jackie accuses Kelly of being inappropriate with two flirty high school girls; Coop begins to let go of childish things; Thor counsels Akalitus on her new phone system and some deeper matters; Jackie is unexpectedly delayed getting to Grace's pageant.

Zoey leads the ER nurses on a walkout. Jackie battles her cravings.

Jackie breaks several rules and regulations to help a 10-year-old girl caring for her lupus-stricken mother; Mrs. Akalitus accidentally tasers herself; O'Hara treats Zoey to a meal at a four-star restaurant.

Longtime ER nurse Jackie Peyton bends the rules to bring some good from a patient's senseless death, while concealing her addiction to a pain killer she gets from her boyfriend, the hospital pharmacist.

Eddie tells Jackie that he now considers Kevin a real friend and can no longer lie to him; Jackie is remorseful when she learns that O'Hara is looking for a new employer; Akalitus announces that All Saints may get a visit from the First Lady.

Zoey finally confronts Jackie. Dr. Prince attracts a mob to All Saints.

Jackie and Grace begin mother-daughter tap class. Coop threatens to expose Jackie for falsifying a donor's record. Jackie has forgotten to remove her wedding ring, and needs to get it off before meeting Eddie for a quickie.

Jackie is forced to perform a procedure on her own. Zoey learns a secret.

After breaking up with Kevin, Jackie has to realize she needs professional help. Meanwhile, a new director at the hospital makes some personnel changes and Kevin finds out about Jackie and Eddie's affair.

Jackie gets inventive, setting her sights on returning to All Saints.

A man is admitted with a steak knife sticking out of his chest. Eddie gives Jackie a Cartier bracelet for their one-year anniversary, but she rejects the gift. A baby is left in the nurses' station and Akalitus takes the infant to her office.

Frank searches Jackie's house for drugs, but she removes them in time and hides her stash in a ladies room at the hospital. Later, Jackie bonds with a homeless, alcoholic nun; and finds comfort in the arms of a fellow drug user. Meanwhile, Zoey confronts Prentiss about his dissatisfaction and encourages him to do what he loves.

Jackie discovers that a new temp nurse is abusing drugs, but when she confronts him, he calls her on hypocrisy; Mrs. Akalitus still has the foundling infant left at the hospital; Coop reveals to Eddie that Jackie has a child.

Jackie and Kevin consider enrolling Grace in private school; the stoic Dr. O'Hara must endure the emotional thanks of a boy whose twin brother she saved; Zoey loses a patient for the first time.

Still strapped for cash, Jackie's dealing takes a surprising turn.

Worried about her daughter, Jackie leaves rehab early against her therapist's advice and finds that returning to work greatly rattles her nerves, forcing her to struggle to maintain her sobriety; Zoey has second thoughts about her relationship with Lenny; Eddie tells Jackie that he confessed their affair to Kevin.

Jackie's back to using again, but she's doing it differently this time: maintaining a clean and sober cover, going to 12-step meetings - even finding herself a sponsor - all the while getting her drugs from the towel girl at the gym. Meanwhile at All Saints, Zoey finds out that everyone knows about her 'secret' relationship with Prentiss. Season premiere.

Jackie detoxes at home - with help. Frank raises an objection about Grace.

Jackie is ambushed by Antoinette. Coop's dream finally comes true.

Jackie and Eddie make a purge their stash. Dr. Prince and Akalitus bond.