When HR demands urine samples from all the nurses, Jackie tries to avoid it as long as possible as well as her husband, who seems to have found out about her affair with Eddie.

Jackie runs out of drugs and Dr. Cooper decides to compete with Dr. O'Hara for the E.R. chief position.

Jackie covers for Cruz when he has a panic attack; Zoey surveys her coworkers for the best ways to conduct a breakup; Akalitus enlists the staff in an elaborate charade when her mentor is admitted with dementia.

In order to get a phony prescription, Jackie falsifies an MRI. In the meantime the campaign's end has its effects on Coop and Eddie is back as the hospital's pharmacist.

Coop gets a surprise. Jackie hits the road. Season finale.

Akalitus forgets to hire an escort for a psych patient who then lays waste to the pharmacy; Frank cancels a lunch date with Jackie; Zoey hears Coop and Carrie having sex; Jackie worries about Frank when she learns that a cop has been shot.

Coop arranges a date for Georgia and Eddie while Jackie's daughter Grace starts therapy.

Mrs. Akalitus is in a holy uproar as workers from the archdiocese remove her religious statues. Meanwhile, a new temp nurse makes his presence known in the ER, and some people don't appreciate it; Coop deals with personal, professional and podiatric problems; and Jackie tries to deal with Kevin playing matchmaker between Eddie and his sister.

Jackie finds a new hiding place for her pills and buries the hatchet with O'Hara, who becomes ER chief; Zoey works her first double shift; Kevin invites Eddie to a backyard barbecue; Jackie must tell more lies to retrieve her misplaced stash.

In order to keep her secret credit card a secret, Jackie sets up a P.O. box for the credit card bills. In the meantime, Mrs. Akalitus offers Eddie to come back as the hospital's pharmacist.

Jackie reluctantly attends Kevin's wedding. Carrie makes demands on Coop.

When Cruz learns about Jackie's rehab, he takes revenge on coworkers who have been covering up her drug problems. Meanwhile, Eddie is deposed by Kevin's lawyer; a dumped Lenny decides to take off for Europe; and Coop accompanies O'Hara to her ob-gyn appointment.

O'Hara offers financial help, but Jackie and Kevin refuse to take it. Eddie and Kevin's secret friendship is revealed.

Unhappy about Eddie and Kevin's friendship, Jackie asks Eddie to stop spending time with Kevin. A pharmaceutical company rep provides Jackie with drugs.

Things get out of control in the emergency room due to the recent firings and an overflow of patients who have been diverted from another hospital, causing Cruz to suffer a pulmonary episode and Jackie to step in. At home, a rebellious Grace refuses to go to class unless Jackie transfers her to public school.

Jackie's life gets a little more complicated because of a security guard and O'Hara's longtime affair comes to light.

After their custody meeting, Jackie rear-ends Kevin and wakes up as a patient in her own ER. Kevin accuses her of using. Coop begins covering for Carrie and taking on a lot more work. When Carrie checks on Jackie, she writes her a prescription for Oxy, unaware she's an addict. The most unlikely person asks Jackie out on a date.

Kevin invites Jackie to a midnight rendezvous in order to give her a new wedding ring; the comatose movie critic wakes up but his tastes have radically changed.

Going through rehab, Jackie opens up about the beginning of her addiction. Meanwhile, Coop is the only one being excited about Cruz's ideas.

Kelly wins over the All Saints staff; Kevin finds pills in a dental floss dispenser; a patient soothes Coop's depression; Jackie pockets drugs.

In the Season 3 premiere, Jackie's marriage is strained, as is her relationship with O'Hara after the intervention; Akalitus warns the staff that nearby hospitals have closed down, straining the staff and resources; Zoey publicly confesses her affair with Lenny.

Longtime ER nurse Jackie Peyton bends the rules to bring some good from a patient's senseless death, while concealing her addiction to a pain killer she gets from her boyfriend, the hospital pharmacist.

Jackie's back to using again, but she's doing it differently this time: maintaining a clean and sober cover, going to 12-step meetings - even finding herself a sponsor - all the while getting her drugs from the towel girl at the gym. Meanwhile at All Saints, Zoey finds out that everyone knows about her 'secret' relationship with Prentiss. Season premiere.

Dr. Prince enlists Jackie's help with a patient. Thor reveals a secret.

Zoey finally confronts Jackie. Dr. Prince attracts a mob to All Saints.

Jackie is ambushed by Antoinette. Coop's dream finally comes true.

Still strapped for cash, Jackie's dealing takes a surprising turn.

Jackie is forced to perform a procedure on her own. Zoey learns a secret.

Following HR's inquiry of the missing drugs, Mrs. Akalitus puts Jackie on probation. Meanwhile, Coop plans his wedding and Jackie's daughter Grace wants to be put on medication for her anxiety disorder.

Jackie's back at All Saints - but back to square one in a new role.

Jackie stirs up trouble for the developers. Coop preps for his last day.

Zoey leads the ER nurses on a walkout. Jackie battles her cravings.

A man is admitted with a steak knife sticking out of his chest. Eddie gives Jackie a Cartier bracelet for their one-year anniversary, but she rejects the gift. A baby is left in the nurses’ station and Akalitus takes the infant to her office.

Jackie breaks several rules and regulations to help a 10-year-old girl caring for her lupus-stricken mother; Mrs. Akalitus accidentally tasers herself; O'Hara treats Zoey to a meal at a four-star restaurant.

Picking up with her arrest, Jackie suffers through detox.

Jackie and Kevin consider enrolling Grace in private school; the stoic Dr. O'Hara must endure the emotional thanks of a boy whose twin brother she saved; Zoey loses a patient for the first time.

Jackie and Eddie make a purge their stash. Dr. Prince and Akalitus bond.

Eddie tells Jackie that he now considers Kevin a real friend and can no longer lie to him; Jackie is remorseful when she learns that O'Hara is looking for a new employer; Akalitus announces that All Saints may get a visit from the First Lady.

Jackie detoxes at home - with help. Frank raises an objection about Grace.

Jackie and her husband, Kevin, become concerned that their older daughter Grace is suffering from anxiety disorder; hospital administrator Mrs. Akalitus drinks Jackie's Percoset-laced coffee.

After breaking up with Kevin, Jackie has to realize she needs professional help. Meanwhile, a new director at the hospital makes some personnel changes and Kevin finds out about Jackie and Eddie's affair.

Missing her family and adjusting poorly to single life, Jackie invites Kevin to meet her at a cafe but finds herself served with divorce papers instead of lunch; an attempted double suicide trauma case comes into the E.R.; Cruz institutes a draconian new dress code that is not a hit with his staff; Zoey looks for a new roommate and finds one in the lonely Jackie.