A night at the local superhero bar turns explosive thanks to the evil midnight bomber!

When Arthur goes off on a date with Carmalita on Hobby Night, Tick builds himself a new sidekick - Little Wooden Boy. Swiss Commandoes are after the notebook of Dr. Vahtoss, Carmalita's father and the inventor of Arthur's flight suit. And Blowhole, a giant long-distance running whale, accidentally swallows everyone, forcing the Tick to light up Little Wooden Boy to cause Blowhole to choke them up. Yep, just another day in The City...

Mutant Dino-Park scientist Neil proves to be a major headache.

A clown with a major hang-up. Laugh at him and you'll pay the price.

Sewer Urchin battles his arch enemy, the Sewer Czar, earning the respect of his fellow superheroes.

The Tick is sent into space to blow the ""CHA"" out of the Moon from when Chairface tried to write his name in the moon. He blows the letter C up while he's inside it and gets sent through space. While in space he comes across a fantastically large alien named Omnipotus. The Tick befriends him and becomes a janitor on his body. But Omnipotus is an eater of planets and plans to eat the Earth when they get to it.

A criminal mastermind with an evil plan and a face only an interior decorator could love.

The Breadmaster is an evil baker that uses baked goods to terrorize The City.

A camera crew follows the Tick and Arthur around for a day of crime fighting as they do battle with a unique villain.

Arthur is nursing The Tick, who is infected with a most uncommon cold!

The Mustache, a U.S. secret weapon, escapes from the lab and tries to team up with its counterpart, the Russian Beard. In hot pursuit are Jim Rage and the Ladies of Project: Shave, so the Mustache takes refuge on the Tick's lip. Meanwhile, Dinosaur Neil and Dot plan for their marriage.

Mr. Mental steals a device from Dr. Pendecker that lets him hypnotize Arthur and the Tick into thinking he's a baby so they'll protect him. Unfortunately, Mental leaves the device in the taxi and has to recover it.

The King of the Mole People and his ministers come to the surface for a vacation.

The Tick and Arthur end up in the distant past and uncover a diabolical plot by the Hotel Manager, a man from the future using prehistoric man as staff for his Hotel at the beginning of the universe. They manage to defeat him and free man's ancestors from a life of low-paying minimum wage jobs.

A flunky of air conditioner repair school makes a time machine and goes back and kidnaps the greatest inventors of all time so he can go back in time and reinvent everything.

The Deerfield Aztecs, a baseball team, crashed in Mexico and formed their own lost tribe of real Aztecs. They track their missing shortstop, Carmalita (Arthur's girlfriend) to America but grab Arthur instead. When the Tick and Carmalita pursue, the Aztecs and their leader Wally unleash ""Speak"", some kind of lowly animal that they intend to wed Arthur to. Tick takes a shine to ""Speak"" (as he names him) and he defeats the Aztecs and rescues Arthur.

The Tick and Arthur are chosen to teach Superhero School and a classroom of unlikely heroes. They must rush into action to take on Uncle Creamy, a corporate mascot turned into a evil ice cream cone who strikes out at the company who made him. Meanwhile Uncle Creamy II attacks, trying to kill Uncle Creamy before he tells the heroes what the company is up to.

An alien race called the ""Whats"" kidnap the Tick and Arthur to attempt to thwart their nemesis' the ""Heys"" from destroying the universe.

El Seed has returned and this time he wants to destroy the whole city by making a 400 year flower bloom in ""the bad way"". This flower will bloom in this ""bad way"", when there is no gentle music around. But when Professor Ichibana, owner of this rare & amazing flower, switches flowers with The Tick and Arthur, these accursed superheroes are tossed in El Seed's salad once again. El Seed creates Rosebud, who manages to steal the flower from Arthur. El Seed makes the flower bloom in ""the bad way"", but even he cannot control it's powers. Only the Tick's opera singing can save the City now...

Arthur and The Tick try to rescue Yank, a super-genius, space monkey, captured by an evil ruler.

Dinosaur Neil, palaeontologist, curator of Dinosaur Grotto and one-time giant city-destroying mutant, is marrying Arthur's sister Dot. Chairface Chippendale, The Breadmaster and El Seed have other plans, though - plans which involve tampering with Neil's medication, man-eating bouquets, exploding wedding cake, and The Indigestible Man. And as if that wasn't enough, Neil's best man is... The Tick! It's up to our blue hero, Arthur and Dot to save Neil, with the aid of a submarine and 1,400 pounds of pungent raw meat...

The evil Brainchild returns and using his Nanny-of-the-Apocalypse, captures the Tick and transforms him into a two-headed bird that speaks bad French. Thus rendered powerless, The Tick is auctioned off by Brainchild, and it's up to the other heroes to sneak into the villain gathering and save him.