A gruesome discovery in a city pond leads Dylan and Lizzie to investigate a young man's murder, while Andy rescues one of Dylan's students from a legal bind.

Dylan and Lizzie work to uncover why an Olympic-hopeful figure skater is killed while on the ice. Also, Ryan's case heats up and lands him and Dylan in unusual circumstances and Julian comes to understand why an old acquaintance has returned to New York.

It's all hands on deck to track down the Sleeping Beauty Killer when Ryan and Dylan's biggest lead in the case takes them to a faceoff aboard a ship. Also, Dylan receives troubling news from his father.

Dylan and Lizzie investigate deaths of three family members who were also business partners in a craft brewery. Also, Andy's legal expertise is needed when he and Dylan confront an issue in their adoption process, and Lizzie learns some hard truths about Julian's past.

Dylan and Lizzie investigate the murder of a successful businesswoman who attempted to prolong the lifespan of humans. Also, Dylan and Andy look to continue their adoption search, and Detective Ryan Stock from Nebraska arrives to hunt for a potential serial killer.

Lizzie and Dylan work a case that provokes deep emotions for them when a 9-year-old boy goes missing on the eve of a judge's decision in a bitter custody battle. Also, with Dylan's help, Lizzie confronts some of her past childhood demons, and a major advancement presents itself in Dylan and Andy's adoption search.

Dylan and Lizzie are unable to identify a motive or connection when several average people blow themselves up using suicide bombs. Also, Julian, concerned that Dylan could be exposing himself to past enemies, enlists Lizzie to talk him out of hiring Ashely, a publicist.

Former CIA operative Dr. Dylan Reinhart is lured back to his old life when NYPD Detective Lizzie Needham needs his help to stop a serial killer.

The murder of a young man who recently left his family's religious community leads Dylan and Lizzie to a series of possible suspects, including a short-tempered photographer and a mysterious girl with amnesia. Also, Lizzie's younger sister, Katie, unexpectedly drops by for a visit.

Dylan, having returned to teaching after helping the NYPD catch a serial killer, is called upon again to aid Detective Needham on a complex case involving the murder of a venture capitalist.

Dr. Dylan Reinhart and Det. Lizzie Needham are reassigned to a murder case in Central Park when their investigation into a chemical attack on the subway is taken over by an FBI team led by Dylan's estranged father, Roger. However, Dylan can't shake the feeling that the cases are related.

Dylan and Lizzie are under pressure to deliver results when they investigate the death of Jasmine's friend, the owner of a professional basketball team who died when her car went off a bridge

Two members of an acting troupe are killed using sophisticated poisons; Andy worries that Dylan isn't fitting in, so he encourages Dylan to attend a barbecue being thrown by Detective Fucci.

Dylan and Julian go undercover in a hospital when they suspect an "angel of death" is killing people with non-life-threatening ailments. Also, Lizzie asks Andy for his legal expertise when a personal trainer sues her for accidentally injuring him.