Mystery writer Agatha Christie vanishes, a man known as D.B. Cooper successfully hijacks a plane, and a series of anonymous letters haunts the town of Circleville, OH.

British suffragettes learn jiu-jitsu, Gwendolyn Sanders ignites the Birmingham Crusade, and Judy Heumann leads a sit-in for people with disabilities.

John Pemberton invents Coca-Cola (from wine and cocaine!), the F.B.I tries to take down Martin Luther King Jr. and Stetson Kennedy infiltrates the Klu Klux Klan.

Abraham Lincoln tries to avoid assassination on the way to his inauguration, Francis Scott Key writes "The Star-Spangled Banner," and Edgar Allan Poe feuds with Rufus Griswold. Featuring Charlie Day, Adrianne Palicki, Jesse Plemons and Jason Ritter.

Scientist Percy Julian overcomes racial barriers, Claudette Colvin refuses to give up her bus seat months before Rosa Parks's famous protest, and Joe Louis fights German boxer Max Schmeling. Featuring Jordan Peele, Terry Crews and "Weird Al" Yankovic.

Deborah Sampson goes undercover as a man to fight in the Revolutionary War, Rose Valland rescues art from the Nazis, and Clara Barton becomes "the angel of the battlefield."

Dolly Parton has to leave the man who made her famous, competing lawyers clash in the Scopes Monkey Trial, and Lewis and Clark explore the dangerous West.

Jim Thorpe dominates the 1912 Olympics, Babe Didrikson founds the LPGA, and Jim Abbott becomes a great pitcher despite being born with one hand.

Frances Cleveland uses her public image for good, Edith Wilson acts as president after her husband has a stroke, and Dolley Madison saves American artifacts from destruction.

Fred Rogers fights for public television in front of Congress, journalist Ida Tarbell takes on John D. Rockefeller, and Maya Lin designs the Vietnam Veterans Memorial.

Baron von Steuben whips Washington's army into shape, longtime friends John Adams and Thomas Jefferson break ties, and Benedict Arnold becomes a British spy.

Will Ferrell and Seth Rogen star in this episode about how teenage writer Mary Shelley created her legendary novel, “Frankenstein.”

Charles Sumner gets caned on the Senate floor, Judge J. Waties Waring helps to end segregation, and a slave named Robert Smalls commandeers a Confederate warship. Featuring Patton Oswalt, Johnny Knoxville, Busy Philipps and Brandon T. Jackson.

Al Capone is done in by an easily solved problem, Abraham Lincoln catches a break and police battle with protesters during the Haymarket Riot of 1886.

Mary Dyer wages war with the Puritan establishment, two cunning thieves pull off a $500 million art heist and the most notorious arsonist in New England history is revealed.

The U.S. reluctantly accepts the Statue of Liberty, Sybil Ludington goes on an epic ride to warn of a British attack, and journalist Nellie Bly infiltrates a corrupt mental institution. Featuring Laura Dern, Taran Killam, Juno Temple and Matt Walsh.

Alan Freed becomes one of the first radio DJs to broadcast rock 'n' roll, Kris Kristofferson gets his big break with some help from his hero, Johnny Cash, and Sylvia Robinson creates The Sugarhill Gang. Featuring Johnny Knoxville, Jack McBrayer and Retta.

Carl Sagan and Ann Druyan fall in love over a golden record, Wernher Von Braun pioneers rocket science, and Alexey Leonov becomes the first man to float in space.

An Italian handyman steals the “Mona Lisa,” the “Santa bandits” rob a bank in Texas, and Mossad agents capture a Nazi general who had escaped to Argentina.

Hedy Lamarr designs the first modern airplane wing, Eartha Kitt's activism provokes the ire of Lady Bird Johnson, and Alexis Pulaski's poodle becomes a huge star.

Popé leads the Pueblo Revolt against Spanish colonizers in 1680, Boy Scouts cofounder Ernest Thompson Seton tracks a wolf, the true story of the Roswell UFO conspiracy is revealed.

Marina Raskova forms an all-women air force regiment to fight Nazis in World War II, and smuggler James J. Andrews hijacks a Confederate train for the Union.

A student tunnels beneath the Berlin Wall, Edie Windsor topples the Defense of Marriage Act, and John Wojtowicz robs a bank to pay for his wife’s gender reassignment surgery.

Emily Roebling oversees construction of the Brooklyn Bridge; con-man Victor Lustig sells the Eiffel Tower; Shakespeare steals the Globe Theatre.

Larry Walters pilots a balloon-suspended lawn chair, Phineas Gage survives an iron rod to the brain, and the Greenbrier Ghost’s testimony is used in court.

Forest service ranger Ed Pulaski saves 40 men from a forest fire, and Ted Patrick rescues teenagers from the psychological grip of the Children of God cult.

Carry A. Nation vandalizes bars; Andrew Jackson gets involved in a shootout; Marsha P. Johnson stands up for LGBT rights.

The LAPD is formed to stop the city from devolving into chaos, Rin Tin Tin becomes a global superstar, and William Mulholland figures out how to bring water to Los Angeles.

Moses Fleetwood Walker faces racism in the 19th century MLB, the Chicago White Sox throw the World Series, and the Callaghan sisters inspire the film "A League of Their Own."

Alexander Graham Bell beats Elisha Gray to the patent office for the telephone, Thomas Edison endeavors to launch a filmmaking monopoly.

Woodward and Bernstein blow open the Watergate scandal, actors/brothers Edwin and John Wilkes Booth engage in a tragic feud and Elvis crashes The White House to meet President Richard Nixon.

Bugsy Siegel bets his life on a Las Vegas casino, while the Moulin Rouge breaks the color barrier, Sin City's origins are a popularity contest for J.T. McWilliams and William Clark.

Bessie Coleman is America’s first black woman pilot, and the students of the Little Rock Nine integrate a high school following the Brown v. Board of Education decision.

Wayne Wheeler leads the Prohibition charge, Dorothy Fuldheim paves the way for women in journalism, and Muhammad Ali refuses to fight in the Vietnam War.

Katharine Wright helps her brothers build an airplane; the Kopp sisters fight to protect their home; the Fox sisters stoke the spiritualism craze.

Lead Belly records songs with John Lomax that change the face of music, John Lennon and Yoko Ono almost get deported, and Sam Cooke writes “A Change Is Gonna Come.”

Milton Bradley jumpstarts the board game industry, Roger Sharpe fights for pinball legalization in 1970s New York City, and Bobby Fischer becomes the World Chess Champion.

Charles Ponzi hires a publicist to improve his image; Sadie the Goat becomes a notorious Hudson River pirate; a con man poses as a Scottish royal.

Mayor La Guardia fights the mob over artichokes; Julia Child meets the love of her life while working as a spy; a molasses flood devastates Boston.

Robert E. Lee's estate becomes a burial ground for Union soldiers, a gang of counterfeiters attempt to kidnap Abraham Lincoln's body, and an embalmed bandit makes his way around the country.