Gabriel must verify an apparition of the Virgin Mary in a suburban village. Gabriel must navigate the religious fanaticism of the faithful and the rigid dogmas of the ecclesiastical elite, questioning the meaning of faith. A girl, almost completely drained of blood but still alive, unleashes fear in a country village. Gabriel and Claudia must confront a legendary creature: a vampire. Gabriel, tormented by his powers, must decide whether to leave the Church.

Claudia is taken hostage by Bonifacio Serventi's organization, which uses the moment to initiate a malignant process within Claudia so that Gabriel, in addition to using his dark power against Serventi himself, can use it. For Gabriel, it is the final showdown: caught between Serventi, who wants him to be the chosen one and embrace his dark power, and the Warrior Order, who wants to eliminate him for his very power. Gabriel is alone and risks losing Claudia forever.

Gabriel has left the priesthood to live with Claudia, when his patient and old friend, Francesca, manages to bring to life a demonic monster capable of emerging from a person's dreams and then killing them in reality. The nightmare also interacts with Claudia, who falls victim to it. A young woman hears her dead son's cries deep in the catacombs near her home, and the same sounds are heard first by a medium and then by the local parish priest. Everyone in her family believes she's a poor madwoman, but the girl refuses to give up and manages to contact Father Gabriel and Claudia.

Gabriel Antinori is a Jesuit theology professor assigned to investigate alleged paranormal phenomena. He is also haunted by a past he can't remember. Orphaned, he grew up under the tutelage of Monsignor Demetrio Antinori, the uncle who entrusted him with his first case. Gabriel and Claudia find themselves investigating a case of alleged hemolacria: a young student at Santa Dorotea, a private all-girls boarding school, is crying blood. Gabriel unexpectedly discovers that the phenomenon is linked to a series of drawings that will sow terror and death within the school.

Gabriel and Claudia are far from each other: he is busy searching for his enemy Serventi, she is struggling with a new life to forget an impossible love. But fate forces them back together, and as before, they must solve the mystery of a man capable of healing every physical ailment. Gabriel investigates the mystery of the stigmata: a young nun with wounds that were said to have opened by the will of Christ. Claudia believes this to be a serious religious delusion, but Gabriel discovers an ancient mystical ritual behind the mystery.

The pictures taken by Pietro reach the Directory and compromise the appointment of Gabriel enough to be able to oust him from the new investigations of the Congregation.