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Crews looking for Reese, who disappeared while on a case with the FBI. What he discovers is that his partners disappearance is connected to the conspiracy that had put Crews in jail.

The detectives look into a politician's murder. The victim had been working on a banning of handguns which would cost gun companies millions of dollars. Elsewhere, Crews looks into the new FBI duties of Reese.

Crews and Reese investigate a murder in which it looks like the wife shot her husband, but no murder weapon was found, what they do find is illegal drugs. Crews asks Reese and Stark to cover for him during the search because he has to take care of something. Crews in in for a shock as he tries to track the man he thinks actually committed the murders he was in jail for.

Charlie Crews and Dani Reese try to narrow down the list of suspects when a retired NASA pilot is shot mid-flight; Crews tries to remember who shot him.

Crews's father, Charles Crews, Sr., shows up at his son's doorstep to try to mend fences. Crews and Reese investigate the death of three Russians; Reese falls into old habits.

In the season two premiere, detectives Charlie Crews and Dani Reese are on the hunt for a serial killer when three numbered trunks containing suffocated bodies are found scattered across Los Angeles. With their new boss New York transfer Captain Kevin Tidwell pressuring them to get answers, Crews and Reese race to find a connection between the murders before the killer strikes again. Meanwhile, Ted and Crews attempt to track down the daughter, the lone survivor, of the family Crews was wrongly convicted of killing.

Crews and Stark experience the world of extreme corporate power while investigating the stabbing death of a soldier killed while on leave in Los Angeles.

Crews and Reese investigate the murder of a Zen Master who was buried alive ten years ago. Crews continues to investigate his own case. He finds some proof that his partner's father Jack Reese could be involved.

After spending twelve years in prison for a crime he didn't commit, Charlie Crews rejoins the force with a shiny new Detective badge. Crews, accompanied by his new partner Dani Reese, works to solve the inexplicable murder of a young boy. Crews' unconventional tactics put Reese on edge causing both Reese and Lt. Karen Davis to question his motives for rejoining the force.

While at an AA meeting Reese thinks she overheard someone admit to a rape. She finds herself in danger because she won't back down and keeps on investigating. Crews goes on a stakeout with Lt. Davis and learns some surprising information about his former partner Bobby Stark.

When a college student is found crushed to death in a wrecking yard, the probe leads Crews and Reese to a complex online love triangle; Crews continues his investigation into Jack Reese by hunting for the officers seen in his latest clue.

A food bank delivery man is found murdered and buried up to his neck, surrounded by flower petals in a backyard. Crews and Reese believe the incident may be related to a cult from the 1970s. Crews confronts Mickey Rayborn, despite warnings from the FBI.

Crews and Reese investigate the murder of two Iranian Americans and kidnapping of another. Not sure if this is a hate crime or not they try to work with the kidnappers. What they uncover is a boy trying to his mother's love. Earley becomes concerned about Crews' impulsiveness when he wants to buy a solar farm after having a dream.

Crews and Reese investigate a gas explosion in which an IRS agent leading a double life is the victim. Was it an accident or arson? Was the IRS agent trying to be a hero? Crews is once again a suspect in a murder investigation when the detective who handled his case is found dead.

When a new bride is murdered her husband is the prime suspect. Crews has his doubts and becomes determined to help, not wanting to send an innocent man to prison. Crews goes back to the crime scene that put him in prison and discovers something.

Crews and Reese are baffled when the body of a cancer research scientist is found frozen solid; Crews resolves to prove that Jack Reese was involved in his incarceration; Ted asks Crews to be a reference for a business school interview.

Crews and Reese investigate the murder of a runaway girl found dead under a freeway overpass holding her guitar. A grocery store employee and his son become the prime suspects when they find out the girl used to play her guitar in front of the store. During the investigation they find ties to a kidnapping 12 years earlier. Are they connected?

A lead singer of a heavy metal cover band is suffocated to death; Crews discovers that his father's wedding has been called off.

When a husband and wife are victims of a carjacking the wife is murdered. Crews and Reese become suspicious of the husband when he refuses to identify the suspect and they have to let him go free. Crews goes to see the detective that handled his case.

When a sheriff’s deputy is found murdered on an Indian reservation, Crews and Reese find themselves in the middle of a turf war between Tribal police and the county sheriff’s department. The detectives learn the victim was not well-liked on the reservation and the opening of a new profitable casino may have led to the deputy’s demise. Crews attends a fundraiser thrown by Mickey Rayborn, one of the individuals Crews believes was involved in the conspiracy against him.