Artist Dylan Schwarz and his assistant Elke arrive on K2 to set up a kids art project. Pippa is attracting the attention of Dr Kersley and obstetrician Dr Tatty Oxford, who in turn has a surprise of her own to spring on Den. Kim confesses that Dave has been offered a job in Iraq, Den ponders her own unexpected news and Pippa makes a discovery of a different kind in a corner at Chatters. Dylan's endeavours help solve one patient's diagnosis, but off the ward Den's announcement ends in a more brutal fashion with fisticuffs for Hilary. With Vag-At research a success, Pippa celebrates funding approval with a suitably open-mouthed Josh, who has a final surprise of his own to spring.

It's a new day, it's a new dawn, it's a new ward. King Edwards has shut, B4 is no more. Kim, Den and Pippa have moved to neighbouring St Jude's in anticipation of a now-stalled redevelopment. Their new home, twin-bayed K2, is modern and clean - all appears well. But behind the glossy facade lie the same old patients and problems, and beyond that comes a long list of new worries. Kim is barely keeping her head above water, home life for Pippa is no more settled, and Den is about to discover her own brand new challenge. With Hilary Loftus looking for efficiency savings and diversity cup cakes on the menu courtesy of modern matron Damaris, the staff once again get on with the daily task of getting on.

Hypochondriac Mrs Dethick is re-admitted, adding to Den's problems, while Megan is having trouble drumming up support for the forthcoming strike. Kim reluctantly turns to Damaris for help with her studies. Starring Jo Brand, Joanna Scanlan and Helen Griffin.

A few days have passed and the stormclouds have continued to gather. Damaris has gone, Megan is angry, Den is playing games and Mrs Dethick is back on the ward. On a positive note, Hansley has turned out to be something of a star turn and the Vag-At is going from strength to strength - at least it was, until a mix up with the oncology Christmas card competition leads to complications. A delicate situation needs careful handling, as a funny turn with the coma patient has unexpected consequences. Back on Red Bay, there's bad news for Mrs Dethick and a bittersweet moment as Pippa again defuses a tricky situation and still finds time to settle up with Hansley.

Another shift, another shuttle bus to miss. The appearance of Dr Kersley and his commissioning consortia plans hints at the changes ahead for K2. Den enjoys her new-found treats, nice Damaris has her feet firmly under the desk, Kim makes a bold career move and Pippa deals with a pressing legal issue. Vag-At research under way, Dr Moore has plenty to take her mind off marital disharmony until a nasty online surprise brings her crashing back down to ground. But it's her cafetiere, brought in from home, that steals the show courtesy of Doris and a mix-up with the dementia care assistant.

Kim has unwisely banked on her annual assessment with Nurse Flixter being a formality with a modest pay rise in the bank. Pippa's future is under scrutiny for different reasons as she reflects on life away from B4. Mrs Fyvie's decline continues, with Beedy at her bedside. And the new wing may have found a new life.

The legacy of the Ivy fight has left a problem, with Hilary accusing Kim of making an inappropriate remark during the fight and insisting on disciplinary action. Kim has called in her union rep to defend her, but the meeting does little to sort out the mess. In revenge, Hilary demands the ward be shut down for a deep cleaning, forcing extra work on the staff. Pippa leaves for a health conference abroad, with her stool sample research complete.

Ward B4 is a world of slips, trips and hips, where health care is at its least glamorous. Sister Den Flixter, Nurse Kim Wilde and Dr Pippa Moore assemble for ward round. The daily grind of new admissions and discharges has begun, but Hilary Loftus, the new male modern matron, has just started work and an unsavoury stool sample and a dead patient give him cause for concern. Kim finishes a slice of the dead patient's birthday cake and heads for home.

Pippa is preparing her research paper and Den and Kim deal with a male referral, but it is problem patient Ivy who dominates the day. Aggressive and deeply unpleasant, she sets a chain reaction in motion that sees Hilary in tears and Kim in trouble. Elsewhere on the ward, life and death continues as normal, but with the MRSA statistics up it seems another crisis is just around the corner. Meanwhile, Den and Hilary are starting to bond.

Kim, Den and Pippa struggle through another normal day on B4. Kim has an unknown female to occupy her, Den has Hilary to cope with and Pippa has a ward round. New patient Mrs Fyvie is admitted, but it's her daughter Beedy who needs to be dealt with.