After an American CEO living in Prague is extorted for millions in cryptocurrency and his family is kidnapped, Mitchell receives a surprise visit from his ex-girlfriend, FBI Special Agent Ella Driscoll, who wants the Fly Team’s help on the case.

When the star witness in the case against Greg Csonka, the man responsible for the death of Wes' former partner, is beaten to death in a Budapest prison before he can testify, the Fly Team attempts to salvage the case to secure Csonka's conviction.

When a private jet carrying American citizens is shot down outside of a small town in Poland, the Fly Team looks into the man who missed the flight. Also, Forrester is conflicted when he receives information from his mother.

When a televangelist on the FBI’s most wanted list surfaces in Gibraltar to seek asylum, the Fly Team’s attempts to take him down hit a roadblock as they face political stonewalling upon arrival to the region. When the predatory preacher goes after the daughter of a disciple as his next target, the team must abandon protocol to intervene.

When an American student is found dead at a prestigious UK university, the Fly Team investigates an infamous secret society. Smitty’s personal history with the school comes to a head when she’s confronted with the same old-world elitism.

The team races to find a kidnapped American teen in Austria as the clock ticks on Forrester's reassignment.

When an American official in charge of a high-profile three-way prisoner swap in Belgrade is detained in Romania, he requests the Fly Team step in and carry out the exchange. When their convoy is attacked and one of the prisoners escapes, the team must do everything in their power to find the missing prisoner before the highly sensitive mission is compromised.

When an American businessman is gunned down in Bratislava, the Fly Team must work with an unscrupulous local detective while safeguarding the sole witness, a fearful tourist from Wisconsin being held by police. Meanwhile, Quinn begins to feel pressure from her brother to deliver information on Mitchell.

When a Russian missile is stolen and put on the black market in Budapest, the Fly Team must secure the weapon before a mysterious American arms broker delivers it into the wrong hands.

When a psychologist with national security intel goes missing on a hike in the Swiss Alps, the Fly Team works alongside a friendly face, Agent Tyler Booth, to find him. Meanwhile, Mitchell receives unnerving news regarding his biological father.

After a young American woman is brutally murdered in Venice, the Fly Team is met with hostility when they discover that their person of interest has ties to a well-connected Italian family. Soon, the case gets even more complicated when the CIA Station Chief shows up with an agenda of his own. Meanwhile, pressure mounts on Quinn to deliver intel on Mitchell.

The Fly Team heads to Oslo when they are tipped off that two Norwegian prisoners are being held in Russia.

When the abduction of an American architect in Rome appears to be connected to a brewing terror threat in New York City, FBI’s Jubal and Nina join Forrester and his Fly Team in Italy as they work together to find the missing American and shed light on the terrorists’ U.S. target. The crossover continues on FBI S05E17 Imminent Threat (II) and FBI: Most Wanted S04E16 Imminent Threat (III).

When a Russian biochemist is assassinated for trying to defect with his highly sensitive biotoxins research, the Fly Team springs into action to protect his daughter, whose father’s last wish was that she get his research to a trusted American microbiologist. Meanwhile, Mitchell stays behind to help Vo during her recovery, and Booth clashes with Smitty when he finds out she could jeopardize his promotion.

The Fly Team, with the help of their new intel analyst, Special Agent Amanda Tate, works to clean up the pieces left behind after a massive explosion rocks headquarters and their key suspect slips away.

When an American man is kidnapped in Warsaw alongside a Ukrainian woman he met on a dating site, the Fly Team heads to Poland to track down the mastermind behind the site.

The deputy inspector general calls on Tate, who is fluent in Spanish, to take on her first undercover field mission, joining Wes and the team in Spain as they investigate a seemingly dirty U.S. Drug Enforcement Administration special agent working out of Madrid.

When a local predator begins extorting underage American girls online, the team attempts to bring the offender to justice with on-site help from one of the victims; Kellett decides she should find a roommate.

The Fly Team leads an international manhunt when an American woman and her new husband flee from Baltimore to Istanbul with her young son after a heinous murder. Also, Vo partners up with Special Agent Riley Quinn, who was not only sent to Budapest to work her first big case alongside The Fly Team but to also clandestinely investigate a member of the team.

When a former U.S. Marine is detained in Istanbul on a charge of smuggling antiquities, the Fly Team races against the clock to organize her release before the Turkish police learn the truth behind her visit

When an ex-FBI agent suddenly resurfaces in a brutal Tripoli prison, Forrester and Powell risk everything to go under cover as prisoners to break him out; the fly team adjusts to their new and improved HQ.

A member of the Fly Team goes missing as the hunt for Greg Csonka continues in Paris. Meanwhile, Vo’s life hangs in the balance after being shot.

The Fly Team heads to Bulgaria in search of a wanted criminal who is exploiting underage American girls. Meanwhile, Raines becomes curious when Forrester asks him to keep an eye on Powell.

When a disgraced former U.S. cabinet member is arrested in Vienna, the Fly Team is sent to investigate whether he and his assistant were peddling classified government documents. Powell struggles as he is forced to stay behind on desk duty.

The International Fly Team is called on when a young mother flees to Hungary with her son, after losing partial custody of her son in the U.S. However, after the boy is kidnapped from his mother in broad daylight in Budapest, the team questions which parent is the danger in the child’s life

The team investigates the death of an American lawyer working out of Budapest, Hungary, after his is killed by a car bomb; Kellett begins to grow close to Hungarian lieutenant Benedek Erdős as the critical case progresses.

When an American family's lavish sweet sixteen celebration is cut short after the mother of the birthday girl is found dead near their European estate, the Fly Team heads to Monaco to find the woman's murderer. Vo begins seeing Raines in a new light.

The Fly Team jets off to Portugal when the daughter of a prominent American hotelier becomes the primary suspect in the murder of an employee. Also, Raines becomes concerned about Vo.

The Fly Team and new Europol liaison Megan “Smitty” Garretson investigate when an American police detective on the Federal task force is murdered in Paris while looking into a U.S. company suspected of selling illegal weapons in France and the Middle East.

When an American vintner is shot and killed on his wine estate in France, the team must determine if the region's local protest group with a history of violence against foreigners is to blame.

The team investigates an American citizen who is proclaiming his innocence after seeking sanctuary at Madrid’s U.S. embassy while still covered in the blood of his murdered Spanish boyfriend. Also, Vo and Raines continue to grow their friendship.

The team investigates when the hijacking of millions worth of cryptocurrency en route to a safety vault in Switzerland leaves an American transporter dead and another on the run.

The Fly Team heads to Vienna to find the culprit of an acid attack on a rising American prima ballerina. Also, Smitty receives some troubling intel from a familiar face.

The Fly Team works to hunt down the sniper responsible for killing an American during an attack targeting a biomedical lab in Belgium. Also, Jaeger clashes with her boss at Europol over her allegiance to the Fly Team.

Special Agent Scott Forrester and his Budapest-based FBI fly team head to Croatia, after Isobel Castille enlists their help to capture an American fugitive who escaped to Zagreb with a 14-year-old girl. OA continues with the mission overseas, intent on bringing the fugitive to justice, while Europol agent Katrin Jaeger attempts to help the team secure the necessary support and access from the less-than-cooperative local authorities. The crossover starts on FBI S04E01 All That Glitters (I) and FBI: Most Wanted S03E01 Exposed (II).

When a group of Americans are among the victims of a bombing at a festival in Budapest, the team is brought in to find the perpetrators before they strike again. Also, when Vo's new beau is injured in the blast, she re-evaluates what dating truly means while in the bureau.

The team races through the streets of Budapest to put a halt to a major art heist about to be perpetrated by an American; Forrester grows angry as Dandridge watches every move the team makes.

The team and Smitty head to Morocco when a commercial aircraft flying from New York to Athens is grounded and an American citizen on board goes missing; Kellett's relationship with Erdős continues to blossom.

When an American businessman’s bodyguard and girlfriend are kidnapped a few feet away from him in Barcelona, the Fly Team questions if the man is as innocent as he claims. Also, Raines grows closer to Maya, the owner of the team’s favorite local bar.

The Fly Team lands in hot water when Vo is found at the scene where a Hungarian gambling regulator was murdered.

After a cybersecurity expert robs one of Switzerland's largest and most secretive banks, the Fly Team is called to track down the fugitive. Also, Smitty's loyalty is put to the test.

The Fly Team and Smitty reunite with Jaeger in Berlin as they all delve into a case involving an unidentified American who killed an elderly German man who appears to have been a covert asset of the ruthless Stasi in East Germany during the Cold War.

When an American founder of an illegal adults-only site is killed in Prague, the team is tasked to locate his co-founder, who is still on the run in Czech Republic; Kellett struggles to maintain a relationship with her mother.

The team investigates an American journalist’s death by poison after his attempt to meet with an anonymous source in Poland. Also, Kellett takes Forrester to task for being overprotective with her during the mission.

Vo goes under cover when the team investigates the mysterious death of an American model in Milan; Kellett is caught off guard when Dandridge arrives looking for visibility on the case.

Vo’s friend from the U.S. Navy calls in a favor to help find her missing nephew in Crete. Meanwhile, Forrester hangs back in Budapest to take care of personal business.