The Matsuno brothers try to adapt their show to contemporary times, with mixed results.

In the 1960s, Iyami comes across a blind flower girl named Okiku and, despite being poor himself, tries to help her raise money for eye surgery.

Karamatsu ends up as Chibita's apprentice at his oden stand. Meanwhile, Jyushimatsu falls in love and his brothers try to help him achieve his romance.

Matsuzou becomes hospitalized, leading the brothers to seriously think about their lives and get proper jobs to support their family. A chance meeting with Totoko sets Osomatsu's mind straight...

The Matsunos and Iyami are killed in a freak plane crash, sending them to Hell. In mourning, the others ponder a way to bring the status quo back to its rightful place with the help of someone near and dear to them.

Karamatsu gets kidnapped, but his brothers don't do anything. Later, a cat gets to speak and read minds, which causes mayhem for the Matsuno brothers.

The Matsuno brothers compete to ensure their divorcing parents will care of each of them. Meanwhile, Totoko asks the brothers for help in a crisis.

Classic children's tales retold with an Osomatsu bent. A Dog of Flanders with many ludicrous variants of Nello and Patrache's deaths, Snow White has a mysterious power, Hansel and Gretel get diplomatic, and several cranes repay their debts to one very generous old man.

The characters renew their contracts with the production committee, but the sextuplets have reservations about the season's success. The sextuplets go clothes shopping. Choromatsu meets with a high school friend, and reminisces about a dark secret they share.

Another collection of miscellaneous skits, featuring Ichimatsu as a pessimistic policeman, Chibita trying out a new gimmick for his cart, Osomatsu receiving the death penalty, and Choromatsu's miraculous reincarnation as a mosquito.

Salmon and Pickled Plum look back on the last two-and-a-half seasons of the series in a clip-show episode.

Yet another collection of random skits, with Dayon's live reaction complimenting. Chibita tries selling some sextuplet meat buns, Choromatsu files his taxes, Osomatsu accuses his brothers of stealing his wallet, a fierce wave of pollen hits town, Totoko tries to escape a creepy maze, raccoon Jyushimatsu cleans his food, Todomatsu tries doing something crazy, kindergartners visit a bread factory, the Proper-Rangers prepare to set off, and Osomatsu takes part in an Olympic skeleton event.

The 10-year-old Matsuno sextuplets of Osomatsu-kun are given a glimpse of the future and see they're going to get fat, greedy and beaten up by angry girls.

A collection of unrelated shorts starring the wild and wacky cast of Osomatsu-san. A trip to outer space ends in disaster, the Pachinko Police are called in, and a familiar-looking puppet serial killer who can't seem to find the right sextuplet for his reverse-beartrap are among the skits featured.

Totoko is jealous when those she knows find more success than her. Meanwhile, Choromatsu manages to land a job and moves out of the house, with the other brothers soon following suit, leaving just Osomatsu alone.

The Girlymatsus attend a wedding and try very badly to pretend to not be jealous. / Wanting to become the main protagonist of the franchise again, Iyami holds a bizarre kart race to determine who the real star of Osomatsu-san will be.

Ichimatsu gets a job interview at a cat cafe, but when in Rome, he does as the locals do. Later, in an apocalyptic world, F6 battles against Iyami and Dekapan, who are robbing the dry-skinned citizens of all of their lotion. After, Ichimatsu is forced to pretend to be Karamatsu after Osomatsu catches him trying on his clothes.

Osomatsu, Karamatsu, and Jyushimatsu share their expectations for the new season. The Riceballs estimate the value of the sextuplets' friends, causing embarrassment. Magical powers are given to the wrong girl.

The brothers try their hand as streamers after being chastised by their parents for not having jobs. Later, Iyami uses an experimental detergent to keep his suit clean, but after being confused by the Matsunos as an expensive liquor, is revealed to turn anything invisible (up to a point).

The Matsunos are invited to Hatabou's birthday party. / Iyami discovers that his buckteeth contain a rare metal.

The sextuplets catch a resilient cold. Later, the brothers question Todomatsu about all the things he hasn't told them about his personal life. Afterwards, Choromatsu plays a paranoid vice-principal overly worried about plans for his school's cultural festival.

The Riceballs prove their worth. The sextuplets try to decide on hypothetical pizza.

Another tidbits collection is here! Astronauts, yokai, and Governor Jyushimatsu await.

Osomatsu-san returns in an all-new family-friendly incarnation! Surely nothing will go wrong, right?

The Riceballs test out some comedy material. Dekapan hosts an imoni-cooking competition.

The sextuplets get a craving for watermelon, unbeknownst to an intergalactic invasion being underway.

The sextuplets spend a lazy Tanabata with friends and neighbors.

The sextuplets and their friends get ready for a mysterious temple festival.

After the festival, the sextuplets get some rest to ease their injuries. / Two fishermen (Todomatsu and Karamatsu) meet a fishing hermit (Jyushimatsu).

The prehistoric sextuplets fool with nature for the last time. Several thousand years later, in a parody of Romance of the Three Kingdoms, Emperor Osomatsu and a group of bizarre generals attempt to take over the country. Meanwhile, in the real world, Osomatsu joins Todomatsu at a mixer, struggling to keep his perverted instincts in check.

Osomatsu and Totoko host an end of year special broadcast, looking back on previous episodes to determine which of the brothers is the biggest loser.

A series of end-of-year skits. Osomatsu and Choromatsu try to do one thing that could make them say they had a good year, Ichimatsu gets persuaded to take part in a lottery, Dekapan and Dayon pound mochi together, Hatabou gets pestered by some greedy Jizou statues, and Choromatsu sends some untruthful New Years' cards. During the second half, a news crew documents Todomatsu, who was let go from the Matsuno family the previous year and is forced to try out for a reserve team.

A series of summer-themed skits. Jyushimatsu takes part in radio exercises, Iyami and Chibita try to beat the heat, Todomatsu keeps finding himself exiled by his brothers, Karamatsu tries to inject summer into everyone's lives, and the sextuplets attempt to talk to girls on the beach.

Ichimatsu struggles to get any sleep with his brothers being noisy all night and refusing to turn off the light. Unable to take anymore, Ichimatsu starts monitoring the brothers' courtesy towards each other, leading Osomatsu to get criticized the most. Later, Iyami proves his skills at the arcades by playing games at their highest difficulty.

Karamatsu tries to take on various requests from everyone to look like a reliable brother, only to take on more than he can handle, so Choromatsu tries to teach him how to refuse. Totoko begins working at a company, proving to be a handful for her superior Todomatsu. Later, a pair of seiyuu attend a dubbing session of an episode of Mr. Osomatsu, witnessing how the sextuplets do their work.

Dekapan and Dayon are drafted into a rousing aerial dogfight. Choromatsu takes the brothers on a day trip to Mt. Takao.

Sanematsu has been resurrected to serve the public trust, protect the innocent, and uphold the law. Meanwhile, the sextuplets have become fully functional members of society, but Iyami and their father suspect something intergalactic at hand with the power of a strange pair of sunglasses.

Nyaa has a rather surprising crush that happens to be Osomatsu and literally everyone tries to stop her from making a terrible life choice.

A rainy day forces the sextuplets indoors, leading to a series of events involving Ichimatsu's bad new haircut.

After their fan breaks, the sextuplets set off on a time travel mission to recover the fan when it worked, with many failed retrievals made along the way.

The brothers quickly abandon their new lifestyles upon learning they have been invited to a baseball tournament for the finale.

Already angered over the sextuplets refusing to paying off their oden tab, Chibita vows revenge on them after they pluck out his one-and-only hair. That night, Chibita begins taking out the siblings on by one, shaving all of their hair and stuffing oden in their bodies.

Doo-wah! The expedition team of Iyami, Jyushimatsu, and Hatabou search for the Devil Yeti. Ichimatsu becomes paranoid when lucky things happen to him all day, so he and Jyushimatsu try to punish themselves to balance things out. A lovey-dovey couple go to a hot spring inn that's haunted by a zashiki-warashi named Osoma.

A series of Christmas-themed skits. Among those included are a zombified cold open, Ichimatsu disturbing a happy couple on a date, an F6 holiday fantasy, and the Annual Matsuno Family Christmas Gift Exchange.

The prehistoric sextuplets return, partaking in dangerous sports. Later, in modern day, noticing their father acting strangely, the brothers discover that he is worried that there's not enough spark in his marriage. After embarrassing himself in front of his sons, Matsuzou considers a love potion from Dekapan, but is this really the best way to patch things up with the love of his life?

Todomatsu holds auditions to take one of his brothers with him to a mixer, struggling to find anyone worth taking. Meanwhile, Iyami meets a kung-fu master who believes him to possess a special technique.

Prehistoric versions of the brothers invent ways for them to relive any pent-up urges, with varying degrees of success. Later, Choromatsu and Ichimatsu struggle to make conversation with each other. After, Totoko takes part in an eating contest but keeps getting distracted by the brothers and guest star Shouei.

A salaryman named Sanematsu takes care of his six siblings, the Matsuno brothers play the roles of a friend group of working girls, and Choromatsu gets caught during a private moment.