Renowned bear handler Jeff Watson says goodbye to his family and friends and sets out on an adventure into the wilderness of Southern Indiana to teach his two 700 lb. grizzly bears Bob and Screech how to survive on their own in the wild.

Jeff's first lesson for Bob and Screech is teaching them how to fish, but it's more difficult than he imagined, and Bob appears to be falling behind Screech.

Bob's injured foot is a concern as Jeff teaches the bears to forage for food. Later, Jeff shrugs off a slash to the arm, and faces the prospect of a future without Bob and Screech.

Jeff’s unconventional hunting lessons fail to prepare Bob and Screech to hunt game in the wild, but he discovers they may be learning on their own. Meanwhile he reminisces about Grizzly Adams and agonizes over eventually parting ways with his bears.

Jeff makes progress teaching Bob and Screech how to feed themselves, but now has to prepare them for winter hibernation.

Jeff's last, painful lesson for the bears is teaching them how to be afraid of humans, but he still wonders if they'll be able to survive in the in wild without him.