Saturday night fever grips New Orleans as the EMTs respond to a gruesome stabbing, an assault with a beer bottle, a car accident involving an infant, and a combative patient who tries biting the hands that treat him.

The unexpected reigns in the city of New Orleans as EMS responders answer calls about a child shooting, a multiple-vehicle car accident, a reported suicide attempt, and a veteran struggling with a drug overdose.

The New Orleans EMT team treats patients suffering from a wide range of painful traumas, including a motorcycle accident victim in danger of losing a limb, multiple seizure sufferers, a young child with a breathing obstruction, and a perpetrator whose condition makes him a danger to himself--and others.

EMS responders face an unpredictable night of crises including a violent facial attack, a high school football injury, and a heroin addict's emotional vow to get clean.

On the 10th anniversary of Hurricane Katrina everyone in New Orleans and on the Nightwatch recall their experiences with the storm and reflect upon the significance it still holds in their lives. Amid the remembrances, the city still needs its first responders. Over the course of a busy run of calls for EMT's, the police SWAT team looks to execute a high risk raid. The people on Nightwatch will do anything to protect their city.

An EMS captain juggles the challenges and rewards of being a wife and mother of twins with the never-ending drama of the job; the shift includes a bloody car accident, a major apartment fire and multiple victims struggling to breathe

Like any dad, Titus wants the best for his son. As an EMT he sees just how dire life can get. From drug addicts desperate to kick their problems, to assault victims, to a teenager who drove his car into a tree, nights in New Orleans reveal the struggles of life in this city. Police officers continue to work tirelessly to get guns off the street which makes the city a safer place to live.

Titus and Dan treat a woman who was viciously stabbed in the face, and Holly and Nick tend to an emotional young transgendered woman who was assaulted. A wild police chase ends with a major car accident, and the firefighters of SQURT 16 race to put out a structure fire. Throughout the long night the character of New Orleans' residents shines through in dramatic and quirky ways.

Every night, the members of the Nightwatch are reminded in new ways to be thankful for what they have. Titus and Dan resuscitate an overdosing drug user just before all hope is lost. Brooke and Landon tend to a young girl with congenial heart failure. Later, a team of firefighters contain a fire before it can wreck havoc. Things get a little bit lighter when Titus and Dan learn that a familiar patient is also a secret admirer of Holly.

With COVID-19 raging across the city, the New Orleans EMS responders face a series of crises that include a vehicle rollover from a police pursuit, a victim with close-range gunshot wounds, and a race to save a woman in respiratory distress.

Not all tragedies are created equal and tonight, when the men and women of New Orleans get word that one of their own has been seriously injured, they all reflect on the risks they take. Other calls during the night mirror that reality. A small party was thrown into chaos by armed intruders and a bar fight ended with a good samaritan getting seriously wounded trying to break up the fight.

The EMT team must band together to treat multiple major vehicle accidents, patients losing consciousness and facing breathing and heart ailments, and a woman who has been assaulted by her significant other.

The brother of a paramedic gets sucker-punched; best friends get into an accident; one of the newest members of the Nightwatch comforts a suicidal patient, then reflects on the bonds he has forged during his first year in New Orleans

The New Orleans EMTs receive calls from every direction, from gunshot victims to seizures to a moped rider playing Pokemon Go.

EMS first responders keep their cool and maintain their spirits as they face a series of challenges across New Orleans, including a shooting and stabbing victim and a woman whose slot machine experience takes a bizarre turn.

It's the week of Mardi Gras and it's the busiest time of year for our first responders. Working the parade route comes with its own challenges and unique cases. Keeley treats a man who impaled his hand on a fence. While Titus and Dan have to navigate through a flood of people to treat a man stabbed in the face. But most drama happens off the parade route. Titus and Dan race to save an 18-year old shot in the head through and through. Randy & his partner Devin, search for suspects in an armed robbery, which leads to a high-speed chase.

The team celebrates the opening of its new headquarters after 10 years of working out of trailers. Titus has received his paramedic license and his long time partner, Dan, must adjust to their new shared roles in a variety of calls. New to the team, Arcady and Ted, get to know each other's styles in their first shifts together.

An EMT first responder juggles the joy of family with the pressures of the night shift, which includes a gunshot victim, a motorcyclist hit by a car, a man in custody, and a Vietnam veteran with a grisly finger injury.

The best people on the job never stop looking for ways to do more better. For police officer Justin, the objective is joining the SWAT team and he takes a big step by leading a raid with the SWAT officers. Meanwhile, the first responders deal with a rash of scary calls, a man suffers from amnesia after getting hit by a car and a woman who fell off a roof. And after a man survives a suicide attempt, Arkady forges a bond with him by sharing the story of her mother's own suicide.

Tempers rise and violence swells during a hot, humid evening; police chase two armed carjacking suspects; Keeley tends to a family injured in a car accident; Titus and Dan respond to a call from a former Playboy Bunn

A young man is shot down while walking home and rumors swirl about who could have wanted him dead.

The legendary French Quarter takes center stage for a busy night of EMT action, as the technicians treat multiple unconscious patients, a young woman assaulted at a party, and a car accident featuring a victim with a tragic backstory.

Strange events are afoot across New Orleans, as the first responders must treat a stabbing and a dog bite on Bourbon Street, a pregnant woman in distress, and an overturned vehicle that could go from bad to worse.

The New Orleans EMS team treats a series of patients in precarious situations, including a woman with an airway obstruction, a man stabbed in the neck, and a pedestrian struck in the French Quarter.

First responders find themselves deeply affected by multiple patients across New Orleans, including an old friend suffering from an overdose and a vacationing nurse dealing with personal trauma.

It's a full moon in New Orleans, and sure enough, all night long, the calls for the EMT's seem to get crazier and crazier: the victim of a machete hacking, the man whose finger is bitten off by a dog, the guy stabbed by a man dating his ex-wife. Meanwhile, two cops keep their perfect record of chasing down suspects in foot races intact, and a fire chief confronts his fear of rats.

EMT first responders answer a wild series of calls, including a man stabbing in the head and a screaming woman who has stumbled onto a New Orleans levee.

New Orleans EMT responders face the darkness of death and the joy of life as they treat gunshot victims and car accident patients and help deliver a baby.

New Orleans emergency response technicians face challenges including a car accident victim trapped beneath a vehicle, another pedestrian hit by a car, and a man with a prior cardiac history experiencing worrying chest pains.

It's Halloween night in Tampa and the cases get wild. Tony and Dave treat a woman who was shot in the chest with a BB gun and is bleeding uncontrollably. The ROC Squad responds to a call from a man who was shot, and Will and Dimitri go into detective mode to help track down the assailants. Later on, Air Control guides Robb and Bethany to track down a fleeing suspect who thinks he can hide in a trash dumpster.

The New Orleans EMS crew reaches out to lend a hand to some down-and-out citizens, including a homeless man fighting an uphill battle on multiple fronts, a man having a panic attack, and multiple shooting victims in the streets.

Tampa first responders have a chaotic night treating seizure and overdose patients, while the ROC Squad Task Force tracks down suspected armed robbers in a high-speed chase.

A strange Mardi Gras sees the cancellation of traditional parades--but not the end of emergencies, as the EMT crew responds to a vehicle-streetcar collision, a motorcycle accident, a house fire, and potential cardiac arrest.

The NOEMS first responders treat children across the city, from kids involved in a car accident to a one-year-old having a seizure, and find themselves touched by the connection they feel to their youngest and most vulnerable patients.

Police officers pursue suspected drug dealers, while Keeley saves a group of partiers from a violent schizophrenic.

The first responders treat a series of major car accidents, a Brazilian soccer player with a knee injury and a hallucinating man with chest pains.

Robb and Bethany are approached by a man who fears his missing daughter is dead; the ROC Squad sets up a high-profile sting to capture thieves preying upon Tampa; Rush and Rutledge try to rescue a puppy from a fire in an apartment complex.

Halloween provides a fitting backdrop to a night on the job that includes some chilling calls. Captain Kevin leads the fire fighters battling a blaze that's engulfed a house, and hopefully nothing more. Police officers Victor and Cedric hunt through a neighborhood in "the country" for a burglary suspect. And on the EMT Sprint Unit, Becca responds to a call she hoped to never get.

Randy and Justin chase down a suspected car thief, while both EMT teams respond to emergency calls involving children in distress.

A dramatic night of calls finds the EMS team facing a range of frightening situations from a bloody machete attack and a shooting to multiple victims struggling to breathe.

Police officers Victor and Lejon join a SWAT team operation hunting a homicide suspect. The fire department tries to save a man who fell into the Mississippi River. And for the EMTs, the calls tonight are as much about comforting victims as they are about saving them.

An EMS officer shares emotional news with his partner; firefighters respond to a call about a vehicle ablaze at a gas station.