The Guardians discover that the Cosmic Seed is back on Earth. In the company of Cosmo, Star-Lord returns to his hometown where he runs into his childhood bully Michael Coogan who is now the sheriff. Now Star-Lord and the Guardians of the Galaxy must find the Cosmic Seed before Korath the Pursuer does.

When the Guardians of the Galaxy's search for the Cosmic Seed continues on Earth, Star-Lord contacts Gorgon where he gets the location of the former site of Attilan. While checking out the area, Rocket Raccoon, Groot, and Drax the Destroyer have visions of the Cosmic Seed energy helping them out like Rocket Raccoon's family being re-evolved, Groot being able to restore the Flora colossi, and Drax the Destroyer being able to see his family again. Even after fighting their way past the Cosmic Seed-enhanced worms and spiders, the Guardians of the Galaxy must keep Ronan the Accuser and Nebula from getting the box containing the Cosmic Seed.

The Guardians and Asgardians team up to rescue Quill from Thanos.

When the Symbiotes escape to Asgard and venomize Thor, Odin and the other Asgardians, it is up to the Guardians to save them, the World Tree and all of existence.

As a comet covered in Symbiotes hurls toward Spartax, the Guardians must team up with Quill's sister to save the planet.

The Guardians and the Avengers team up to find out what powerful secrets lie inside Thanos' asteroid.

The Guardians don't know who to trust as the Darkhawks seem to have duplicated everyone, including Quill.

The Guardians discover Groot's homeworld, Planet X, has been overrun by Symbiotes who will stop at nothing to get Groot's restarted World Pod for themselves to conquer the galaxy.

Now that Thanos has the Cosmic Seed, he takes control of the Earth and molds it into his personal planetary weapon of mass destruction. The Guardians of the Galaxy must work to reclaim the Cosmic Seed from Thanos even when Ronan the Accuser and Nebula plan to dispose of Thanos with plans of having the Earth be destroyed alongside him.

With the Nova Corps defeated and the fate of the entire universe in jeopardy, the Guardians must turn to an unlikely ally to stop The Serpent.

When the cocoon opens and reveals a baby warlock inside, the Guardians have to step in to be a positive guiding force to keep his powers in check.

While trying to dispose of Thanos' asteroid, the Guardians discover it has been taken to a secure facility that belongs to the Avengers.

When Asgard attacks Spartax, Quill and the Guardians become caught in the middle trying to expose the deception behind the conflict.

Cosmo goes undercover on the Believer Flagship but loses his powers when his cover is blown.

The Guardians have to team up with Loki in Asgard when The Serpent infects the World Tree and threatens to destroy the universe.

Following a falling out with his father, Star-Lord finds a ship containing the A.I. Rora as he takes it off of Spartax with the Drax the Destroyer and Groot providing a diversion for the Spartax Royal Guards. Afterwards, the Guardians of the Galaxy have to deal with Lucy and Supergiant who are jilted that Star-Lord is the Prince of Sparta.

After being infused with incredible power from a Nova Helmet, Gamora leads the Guardians and her sister Nebula on a mission to infiltrate the Believer flagship.

As the Guardians prepare to take the fight to The Serpent, they Bifrost around the galaxy to gather reinforcements.

Quill and Gamora battle the High Evolutionary, his minion hybrids and a teleport-hijacking Nebula.

When Rocket and Drax wake up with absolutely no memory of the night before, the Guardians must piece together their adventures.

Warlock has gone dark! By absorbing J’son into his gem, Warlock has become Dark Warlock (Magus) with his sights set on conquering the galaxy, starting with Spartax.

The Guardians pay the Inhumans a visit to learn more about the Cosmic Seed.

The Guardians finally make it out of the Black Vortex, only to find that the galaxy has been taken over by sinister robots called the Darkhawks, who are disguised as their friends.

Quill starts his own talk show after beating Thanos! But to his dismay, everyone seems to hate it, especially the Grandmaster who is rigging the segments to destroy Quill.

Quill finds himself in a claymation world where the Milano is flying into the sun, threatening to melt him. Meanwhile, Groot and Drax must fight Ronan in a Golden Age world.

The Guardians have captured Thanos, but it's no easy task transporting the most wanted criminal in the galaxy.

Drax decides he no longer wants to be a Destroyer and looks into new occupations.

Gamora decides to use her new riches to repay all of the people she has wronged throughout the years. When Nebula shows up, Gamora tries to teach her the value of doing good.

The newly-christened Guardians of the Galaxy come into possession of a dangerous artifact that has Thanos’ new lieutenant, Korath, after them.

While caught in a CG sinister packing factory, Rocket must search for his best friend Groot and escape.

The Guardians now have everything they ever dreamed of, but money can’t solve their problems.

The Guardians must work together to escape the elaborate prisons created for them by The Collector.

Gamora and Quill battle their way through an 8-bit Super Marvel World.

The Guardians squander their riches and take on a simple transport job. It turns out that they are stealing from the Kree, and Phyla the Accuser will do anything to get it back!

The Guardians chase after J’son and Mantis as they try to manipulate Sam to do their bidding by promising him clues to the location of his missing father.

Quill gets mixed up in a game of deceit when Gamora tries to pit her siblings, Nebula and Korath, against each other.

Caught red-handed by Titus, the Guardians are coerced into infiltrating a notorious gang of weapons dealers known as the Black Order.

The Guardians struggle to subdue the suddenly-sprung-to-life Celestial head that is the Knowhere space colony, as well as storm Korath’s ship to rescue Quill, Gamora and the mysterious CryptoCube that holds the Cosmic Seed.

When the Guardians become separated in the Black Vortex, Gamora wakes up in a children’s fairy tale, while Drax is trapped in a comic book.

Phyla-Vell reluctantly teams up with the Guardians to bring The Collector to justice for destroying her home planet.

The Guardians finally make it out of the Black Vortex, only to find that the galaxy has been taken over by sinister robots called the Darkhawks, who are disguised as their friends.

The team stages a Christmas Carol inspired con-job in order to frighten a despot out of his ill-gotten riches and free his enslaved people.

In search of the Cosmic Seed, the Guardians unexpectedly find themselves in Asgard where they must outwit Thor and Angela in order to discover the seed's origins.

In order to save the Guardians from the ruthless asteroid Korvac, Quill must bust J'Son out of prison on Spartax and in the process he sees a new side of his father.

Gamora attempts to make amends for her past misdeeds only to find herself in a deadly trap set by Nebula, Ronan and the Grandmaster.

The Guardians track down Howard the Duck to find out who set them up and why, but they don’t get far before Phyla the Accuser catches up to them to deliver some Kree justice.