When Rachel Kosub is discovered naked, brutally raped, and strangled to death on her office floor, San Antonio police question who could commit such a vicious murder. They struggle to identify a killer until DNA analysis cracks the case, 20 years later.

Winston-Salem in 1982 is a city divided by race. And when a young white copy editor is raped and stabbed to death blocks from where she worked, the atmosphere is tense. Twenty years pass before Deborah Sykes' killer finally faces justice once and for all.

South California is the perfect place to retire, but when an 84-year-old is brutally raped and murdered in her senior living community everyone is a suspect. To find her killer, the investigation goes global as the suspect does his best to slip away.

A murderous attack in Park Slope, Brooklyn, leaves Sylvia Lugo dead and her girlfriend, Amanda Leach, raped and shot in the leg. Police struggle to pin down an assailant without any hard evidence, resulting in Leach being pegged as the prime suspect.

In one of the most notorious missing children cases, Adam Walsh, 6, steps into a stranger's car and disappears. A manhunt is launched but Adam's severed head is found two weeks later. More than a quarter of century passes before the mystery is solved.

In Michigan, a 15-year-old is abducted and strangled, her naked body dumped in a nearby orchard. Police line up a slew of suspects, but the case goes cold. But ten years later, a grand jury dusts off the case, and finds the truth has been there all along.

A former police officer comes home to find is whole family murdered; forensic evidence points to the former officer as a suspect despite his alibi.

Reconstructing the investigation into the murder of a man at an Ohio gas station. The case quickly revealed a web of secrets and lies connected to one of the community's richest families.

Parceled into a series of plastic bags, the dismembered body Karyn Slover is found floating in an Illinois lake. An autopsy reveals she also suffered multiple gunshot wounds to the head. After 2 years and no leads, can forensic science crack the case?

When the body of a San Diego man is found in his burned car, investigators begin a bizarre murder mystery. Many people are possible suspects, but the case goes cold. A woman makes a confession, and a tale of jealousy and cold-blooded murder is revealed.