A wet t-shirt contest at Johnson's bar brings out the wild, side of the Co-eds. While the Co-ed men try to use seduction in order to score points for their bar, Double D's, the Co-ed women get serious about competing as they sponge down and bare all. A certain rock star from James' past is back in the picture.

The co-eds are back but without womanizing party boy, James. Now that he is married to Ophelia he has gone to Florida to seek job opportunities. A series of sexual experiments wins Ophelia a research grant and the opportunity to travel to Florida with her research team, aka the co-ed housemates, in tow. Ophelia is excited about reuniting with her new husband, but can marriage really change the old James?

With James and Ophelia celebrating their engagement all over the condo, Karen, Emmanuelle/Emma and Cooper plan to housesit for a friend and Emma asks Guillermo to go along. Ciara finally is fed up with Larry's blind devotion to Sophie and leaves their latest film causing Larry finally realizes his real muse was always Ciara.

In the season finale, Ophelia receives the news that she won her grant and will be leaving for Borneo in a week. The end of the semester means that friends will be parting and the gang quickly plans a party where a number of surprising twists ensue.

After Karen makes Lisa's sexual history public knowledge, she and the Omega House crew decide to help Lisa find her true love with an Omega House special, a wild Blind Date party.

Students are caught up in a phony campus-wide scare when a video about a fictional serial killer is mistakenly released as real news causing everyone to believe a real killer is stalking unwitting coeds. Add a blackout to the mix and the result is mayhem of the erotic kind.

Ophelia and Lisa go streaking across the campus and wind up stuck in the Dean's office where they hook up, but when Ophelia tells James about the encounter her informs her that the Dean has a security system taping all activities in his office. That sends the couple on a mission to recover the incriminating tape. Meanwhile, Jose and Freddy try to learn the secret of nerdy John Silverman's success with the ladies.

Larry plans a Sci-Fi themed student film with the dual goals, a passing grade and the attention of the girl of his dreams. Cooper offers his unique vision to the project adding a pornographic slant to the production.

Karen tries to cool the passion with new roommate Cooper by setting him up with French exchange student, Emmanuelle, whose is more interested in another roommate. Ophelia considers moving in with Royce who is cheating with another co-ed. James knows Royce is cheating but keeps the information to himself. Karen and Larry continue their sibling rivalry for control of the condo.

Freddy's addiction to pornography causes his house mates to stage an intervention. He denies he has a problem but finally agrees to a challenge. If Freddy goes one week without any sexual gratification, they will leave him alone on the subject. Can Freddy do it even with Karen's sexy attempt at sabotage?

In order to make money for the bar, James hires a hypnotist to perform. The co-ed gang each decides to use the hypnotist to jumpstart their sex lives. James wants to use hypnosis to reveal that Royce is being unfaithful to Jenny. But tapping into one's subconscious may not bring the results that they all hoped for.

Karen's in for a rude awakening when she finds out her family may be poor. Her step-mother (Sydney Steele) comes to town on a hunt for a new sugar daddy. James must decide whether to consummate his marriage or get it annulled.

Karen resorts to kissing a girl to push Brody to leave her. Dick Johnson wants Jenny back -- if not in his bed, then perhaps in his bar. James' brother, Jessie, is back in town and wants to see Layla.

Sex becomes a sporting event for the Co-eds as they spend their last few days in Miami. But it's the sexy games of the Spring Break Olympics that bring the Co-eds toe-to-toe with rival, Dick Johnson. The stakes are all or nothing -- if they lose the competition, they will lose the bar.

Dean Loward decides to let James graduate in order to be rid of him. Zach, Karen and Larry rent a dilapidated Frat House with incoming freshmen Victoria, Maxwell and Olga, and throw a farewell party for James. But will James really be able to leave college life and his merry band of friends?

Now that Lisa has given up her virginal status she is consumed with a voracious sexual appetite, which she sates with Jose at any opportunity. However she is faced with a dilemma; her teenage boyfriend/finance is coming to campus for a visit and she doesn't know how to tell him about Jose.

Jenny has a clever, sexy plan to sabotage competitor Dick Johnson's live commercial broadcast and to shut down his bar and the Co-ed crew goes to extreme measures to help out. Larry spends some time discovering how the Ice Princess got her nickname.

When Jose naively attempts to help a young woman and is jailed his roommates plan a jailbreak.

The co-eds go wild as they try to out do each other in a Spring Break sex competition. Karen and Zack attempts to sabotage each other's sexual conquests may leave them both off the scoreboard. James' past secrets are revealed.

When Dean Loward finally closes a problem fraternity house, the university uses it for overflow housing, placing four freshmen under the supervision of the former fraternity president and his sometime girl friend.