Officers are vigilant after a recent gun show in the United States; a traveler's car is inspected when he tells officers a suspicious story about his travels; a man is caught smuggling pills and must choose between jail or giving up information.

A truck carrying household goods into Mexico is stopped for inspection; when several boxes are X-rayed, a gun and ammunition are found hidden inside a kids' toy box; a man re-entering the U.S. is stopped after checks reveal he is wanted for murder.

A man tries crossing with cosmetic injections stuffed into a sweet treat. A rookie officer follows a hunch after a Canadian narcotics smuggling trend.

When officers see an approaching vehicle make a sudden U-turn, they give chase and find a bag with a gun and ammunition. Tourists arrive with a large amount of Botox and dermal fillers, hinting they may be planning to perform cosmetic treatments for cash.

Agriculture specialists deal with cattle arriving without required seals.

A woman claims she drove 13 hours for a 15-minute dentist appointment, but she can't remember the name of the dentist, and has no proof of her visit. Two men returning from a night in Mexico are pulled over after officers detect a strong smell of weed.

The border between the USA and Mexico is the busiest in the world. This series follows the work of America's Customs and Border Protection agency, whose job is to defend the border and stop terrorists, drugs and illegal weapons from entering the country.

Officers see a trend of narcotics being smuggled inside car dashboards.

K9s save the day, identifying gallons of paint and beer bottles filled with more than the officers bargained for; a man with a warrant for his arrest is concealing something suspicious; officers question the intentions of a chatty traveler.

A man traveling with his young daughter attempts a U-turn before the border and comes face-to-face with CBP officers. A stand-up comedian is stopped after declaring prescription meds, but further analysis shows that the pills test positive for fentanyl.

When an American band is denied entry into Canada due to incorrect paperwork, CBP officers have to investigate. A U.S. citizen coming back from Mexico is flagged as having an arrest warrant -- while officers dig deeper, she attempts to escape.

A man who arrives at the border with a baby is concealing another valuable commodity; a couple who fails to declare Mexican avocados ends up causing a scene; a teenager claiming to be a U.S. citizen arrives looking to attend high school in Texas.

Officers discover firearms that may be intended for a Mexican drug lord; a load of Fentanyl hidden in an ice cream freezer; a truck driver transporting puppies is under scrutiny; a wanted woman is detained in Brownsville.

A cartel hitman is extradited, and 50 gallons of moonshine is intercepted.

When a U.S. citizen returning from Mexico is flagged for having an arrest warrant, the man claims to have taken 20 morphine pills in order to avoid prison time; a shipment of car seat cushions coming into America is padded with more than foam.

A magician comes under scrutiny for traveling with his prop dove.

Following the work of America's Customs and Border Protection agency, whose job is to defend the border and stop terrorists, drugs and illegal weapons from entering the country.

Officers discover methamphetamine hidden inside a truck's speakers and confiscate drugs packed deep within lead boxes; a woman denies trafficking pain pills; a man is interviewed to confirm his citizenship.

When a trailer full of sea salt shows up at the bridge, officers decide to inspect it; the bags do contain a crystalline substance and it's an illicit one; during an inspection of a U.S. citizen, something illegal rolls out of his pocket

Multiple drug busts and arrests get made at various border crossings in Texas, including the discovery of the largest meth haul yet attempted at the Pharr-Reynosa International Bridge.

When an older couple crossing into the US has cartel logos on their packed clothes, they have some explaining to do. A Mexican driver says he's visiting a friend in Texas, but seems nervous. A vehicle search finds evidence of hidden compartments.

When a man waiting in the pedestrian line to enter the U.S. suddenly turns and sprints back toward Mexico, officers give chase; a Mexican national seeks asylum in the U.S. after claiming he was kidnapped and extorted for information by cartels

A former teacher is surprised to find she has a warrant out for her arrest.

Officers discover an illicit load within a shipment of garbage bags.

A truck stolen by the cartel in Mexico comes back to America.

An inspection of travelers leads to the takedown of a cartel stash house.

An elite team prepares for the extradition of a cartel Sicario, or hit man wanted for murder in his home country; with the sale of guns and ammo strictly controlled in Mexico, cartels turn to America for the weapons to wage their wars.

A truck with a compartment of drugs requires a complex code to open it.

A covert load of hard narcotics is found in a tractor-trailer's air tank.

A cavity search reveals a smuggler concealing pills in an unpleasant place.

Officers catch a man trying to enter the US with a manslaughter warrant.

Officers struggle to open up an engine part they suspect is hiding drugs.

A man returning from Mexico requires emergency Narcan after a suspected opioid overdose; an unlikely family is caught trying to smuggle firearms into Mexico; a woman attempting to sneak prescription meds into the U.S. is caught red-handed.

An X-ray flags a dark object in the fuel tank of a a band's tour bus.

A man's in a bind when trying to cross with an item that fell from the sky.

Meth is found inside the walls of a trailer; brothers are caught smuggling prescription medication; illicit Mexican delicacies are confiscated at the border.

A new officer makes one of the biggest drug busts her bridge has ever seen.

Officers uncover a lethal load. A woman and son are caught with fake visas.

Sisters are detained when one attacks an officer after binge drinking.

The cartel tries to sneak one last shipment over the border just before midnight; officers uncover a delivery that isn't what it seems; a woman acting erratically is found with a Santa Muerte statue, indicating she may have cartel connections.

Methamphetamine is found hidden within a semi-truck full of frozen broccoli, a man is caught smuggling pills inside containers of protein powder, a traveler tries to bring a deer trophy across the border, and an intoxicated US citizen is detained.

A couple from Mexico arrives with candy unfit for children's consumption.

Officers question a man traveling with two children that aren't his; a traveler is caught smuggling cash; drugs are found concealed in a flatbed truck; a drunken man is restrained in Progreso, Mexico.

A woman returning from a shopping trip in the US attempts to smuggle dirty money into Mexico; a van full of clothes is hiding an exotic shipment; a man finds a clever hiding place for prescription drugs; a family tries to bring in illicit fruits.