Cristina and Meredith's surgical skills are put to the ultimate test.

In the second part of the two hour season finale, George delivers stunning news to Bailey, sending shockwaves throughout the hospital, and Izzie's friends anxiously await her recovery from surgery. Meanwhile Bailey is surprisingly displeased after being accepted into the pediatric fellowship program, and the victim of a near-fatal traffic accident brings the talents of Seattle Grace's doctors together. This is the second hour of a 2-hour season finale.

Seattle Grace Hospital is hit with a crisis like no other in its' history.

This episode is the second part of a two-hour season finale. Richard tries to get information from Addison about a family member's condition. Callie and George have a talk about his feelings. Meredith and Derek have a talk about Doc.

An explosive case arrives at the O.R. that might endanger all the lives of the people working there, which leads Dr. Burke to declare a "Code Black" for the hospital. Bailey worries where her husband is as she is in labor. Also Izzie and Alex may be creating some heat.

Derek is still operating when he finds out about Meredith's current situation. Meredith is freaking out about her situation. Webber and Bailey are dealing with medical health issues. Cristina and Izzie have their own issues to deal with because of Meredith's situation. Addison freaks out when George tries to find a solution to Bailey's impromtu postponement. Overall, Seattle Grace Hospital is still under code black and the situation is getting worse.

As Meredith, Derek and all of their friends prepare for the big wedding, a group of college students, injured in a car crash as they were heading to their graduation ceremony, is admitted to the ER. Meanwhile, Izzie fears the worst when she begins experiencing familiar symptoms.

The doctors of Grey Sloan Memorial Hospital bid an emotional farewell to the beloved Cristina Yang. A possible act of terrorism rocks Seattle and causes chaos at the hospital. Meanwhile, Meredith makes a life changing decision and one doctor receives shocking news.

Grey Sloan Memorial Hospital enters crisis mode as the storm rages, resources become scarce and patients flood in by the busload. Meanwhile, one of the doctors fights for their life.

Meredith is still underwater, but nobody seems to notice. Her worsening condition makes her rescuing an urgent matter. Derek finds her coat on a man she had helped, and starts looking for her and, much to his shock, the little girl Meredith took care of suggests that she is in the water. Derek saves her, but she is almost dead, due to hypothermia. Izzie has to perform brain surgery on a man stuck between cars, as he begins to experience seizures. She drills holes into his head, perforates his skull and ultimately saves his life before he is rescued and transferred to Seattle Grace Hospital. George lies to the woman whose son he had been looking for, in order to get to surgery, but still doesn't have any luck in locating him. Alex finds no hope in searching for the pregnant Jane Doe's family as she undergoes surgery. The interns find out about Meredith's situation and express their hopelessness. She wakes up in what appears to be limbo and meets her deceased acquaintances.

Denny needs a heart or else. Izzie and George go crazy trying to get him one. Derek has the life of a friend in his hands as he operates on Burke who has been shot. Burke cannot operate on Denny after Denny's heart stopped and now Denny is in a dire condition. Cristina gets put in charge of the ER and she is worried about Burke.

A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.

George and Derek work together, Denny still doesn't have a heart, and Meredith gets paired with Callie. A 12-week pregnant girl dies in the O.R. and her parents try to keep the baby alive. This causes tension between Derek and Addison. One doctor's overreaction unites two bickering patients. Finn is still treating Doc for medical problems.

A severe car crash involving an entire family results in an all-hands-on situation in the ER, as the eldest daughter is left to make the toughest decision of her life. Meanwhile Teddy, still in the dark about Henry's death, calls upon Cristina to help with her patient in the O.R., and Lexie finds herself working alongside Mark's new girlfriend, Julia, during an eye surgery.

On the day of April's wedding, the Grey Sloan Memorial doctors are all preoccupied with their own drama. Meredith and Cristina continue to argue about their research and careers, Bailey comes clean to Ben about her feelings regarding him moving back to Seattle, and Shane puts himself in a risky situation. Meanwhile, Derek gets a phone call that will change his life.

Everyone is pushing for Meredith to survive, or in this case to be revived. People are still dealing with the fallout from the ferry disaster. A young man named Lucas is having problems with brain-mouth coordination. Someone else dies.

The mountain climbers lie about the axe in their friend's head, telling Derek that it accidentally got there. During surgery, he and George discover that it was deliberately put there, and one of the climbers admit that he was trying to "put him out of his misery". Adele is saved after Richard finds her lying in the bathroom and is stabilized, but soon suffers a miscarriage. Richard learns Adele was actually pregnant with his son, not someone she had one night stand with. Bailey is disappointed to see that Callie is the new Chief Resident and begins to question her abilities as a surgeon. Richard chooses Derek as Chief of Surgery, but he refuses, telling him that he isn't done doing what he does best. Cristina and Burke's wedding day arrives, but Cristina won't stay out of the hospital. However, Cristina's nervousness results in Burke's realizing that he does not love the real Cristina and leaves her. Meredith and Derek are uncertain about their future and despite Derek admitting that she is the love of his life, they call their relationship over.

Train Wreck victims come to Seattle Grace and all staff gets called in. Everyone deals with really weird cases. Except Addison and Izzie. They work with a woman who is pregnant.

Faced with a life threatening situation, the doctors must fight to stay alive while trying to save the lives of their peers; Bailey and Ben make a decision regarding their relationship; and Teddy is presented with a tempting offer. Meanwhile, Richard plans a special dinner for the residents.

A mass trauma situation, which turns out to be a ferryboat accident, challenges the whole staff of Seattle Grace Hospital. Richard finds difficulty in coping with his separation from his wife and dyes his hair "for the ladies", which becomes an internal joke between Mark, Burke and Derek. Cristina tries to tell Meredith about her upcoming marriage, but doesn't have the strength to. George promises to find a woman's son, who has been separated from her at the accident. The woman refuses to go into surgery until she is assured that her son is alive. Izzie has to take care of a man who got stuck between two cars on the ferry, but nobody helps her due to the large number of injured people. Alex rescues a pregnant woman with severe wounds on her face, and promises to take care of her. Meredith looks after a girl who has been separated from her mother after the accident, but accidentally falls into the water and drowns, with nobody but the little girl as a witness.

Bailey grows desperate as a patient's condition becomes more and more dire. Everyone in the hospital is stepping up to try to find the boy a new organ donor, including Meredith, who considers a death row patient's wish to die before execution. Meanwhile, an injury leaves Mark in a compromising position in the OR and Cristina awkwardly avoids Owen.

Teddy puts her husband’s life in the hands of her peers when Henry is sent to the OR for surgery and she’s called away on another case; Meredith and Derek receive the long-awaited news about Zola; Callie and Jackson come under fire when their patient experiences post-surgery complications; and Meredith and Alex are involved in a life-threatening situation when they travel to a neighboring hospital to tend to a sick newborn, on Grey’s Anatomy

When a trauma patient arrives at Grey Sloan, it forces Jo to confront her past. Meanwhile, Bailey and Ben have to talk to Tuck about dating.

The doctors’ lives are at risk after a dangerous patient escapes the hospital room. Alex must make a hard choice in his relationship with Jo while Meredith has some big news for Nathan that brings things to a turning point.

Meredith and Maggie support Amelia on an important day; Jo reveals that she has been keeping secrets from Alex while Arizona and Callie deal with the impact of their custody arrangement. Meanwhile, Ben leaps into action to help a friend.

A sexually transmitted disease breaks out and affects several members of the hospital staff. Chief Webber promptly calls a meeting. Meanwhile, the chief reluctantly tells Dr. Derek Shepherd about his own medical concerns. Izzie and Cristina worry about a patient's wife and daughter who can't agree on his care. Burke treats his college buddy Bill, whose medical diagnosis raises some questions regarding his wife's actions. Then just as Meredith and Derek grow more intimate, a surprise is revealed.

The race for the Chief's position is on, and the attending physicians, Derek, Burke, Addison and Mark, compete for Richard's affections by trying to help out everywhere possible. The Denny Duquette Memorial Clinic is open for business, but only one single patient shows up. Izzie is disappointed in what she invested Denny's legacy in, and tries to steal patients from the emergency room. Callie and George get back from Las Vegas, announcing their marriage, much to everyone's disbelief. Izzie is not supportive of their marriage and tries to get George to realize the mistake he has made. Meanwhile, Meredith's Alzheimer's-stricken mother, Ellis Grey, experiences a change in her medical condition by becoming lucid for the day. She is disappointed in the mediocrity her daughter has fallen into and begins to despise Derek, blaming him for what happened to the Meredith that used to be "a force of nature". Ellis has to have heart surgery and, despite her wishes, Meredith schedules her upcoming surgery. Richard talks to Ellis and realizes that she is still in love with him, but loses her memory after their talk ends, before Meredith has the chance to tell her how she really feels.

As word of Seattle Grace's financial trouble spreads, Catherine encourages Jackson to move to Boston, and the interns fear they might lose their jobs. Meanwhile, the doctors meet with a potential investor in a last-ditch effort to save the hospital, and Alex impresses Jo while caring for a patient.

The residents agonize over their oral boards, reliving every answer they gave during their exams; Arizona's close childhood friend comes to Seattle Grace for medical help; the doctors work on a patient who is missing one third of his skull; and Julia asks Mark to start a family with her. Meanwhile Catherine tells Richard that one of his residents has failed.

When Isaac has an inoperable tumor wrapped around his spine, he wants Derek to do the impossible. Derek tests the Chief's authority when Richard objects to moving forward with the risky surgery.

A gunman opens fire at a local college, sending mass casualties to the hospital; Arizona's return is not warmly received.

The doctors of Grey Sloan Memorial Hospital prepare for a super storm heading towards Seattle. Owen's desire to be a parent gets stronger as he becomes closer to Ethan. One wrong move puts the lives of Meredith and her baby in jeopardy. Meanwhile, Jo looks to Alex for help in a moment of crisis, and one doctor gets the shock of her life.

The staff attends to an intern from another hospital who has short-term memory loss. This intern, named Marshall, also has caused a car accident that involved a married couple, their unborn baby and the woman's parents who the staff are also treating. The pregnant woman is named Melanie and she will die but her baby may survive. One of the female interns meets up with a woman from her past who is planning on having a family of her own. Cristina is in a good mood although Alex, Izzie, George, and Meredith are having problems but in the meantime Burke hasn't forgiven Cristina for her late night faux pas. Meredith and Izzie are making fun of Callie's household habits and George and Callie are having a fight because of George's roommates. Addison is continuing to own Alex and he's upset about it. Denny has an outburst at Izzie and Derek has an outburst at Meredith.

After his fellow surgeons try and fail to bring Derek back to work, Meredith must summon the strength to convince him. Meanwhile the hospital is abuzz as Mark attempts a rare face transplant surgery. Cristina, at last awarded her first solo surgery, is more focused on the needs of her friends, and Izzie does her best to keep her medical condition a secret.

Cristina and Meredith try to figure out if Cristina should tell Burke that she's pregnant right before Cristina faces an emergency. Alex and Izzie get closer while Meredith's mother gets too close.

Derek and Addison's relationship is rocked to the core when a former friend comes to Seattle Grace and his presence promises to shake things up for a few members of the staff. Burke and Cristina's relationship is affected when one of her secrets is outted. Alex and Izzie are having similar reactions to their closet scenes during the Code Black crisis. On top of this a cocky doctor shows up to piss Derek off in all kinds of ways. A patient is suffering from constant orgasms and her condition sparks interesting conversations among the staff. George is trying to figure out how to get Meredith to see him as more than just a housemate. Another patient, that Derek is treating, is dealing with a rare disorder and needs his parents support and understanding. Burke has a patient who inspires him to talk to Meredith and Cristina about doing what they say they will. Meanwhile, Meredith learns more about her family (in fact maybe more than she may have wanted to know) through her parents.

In this Meredith & Cristina-centric episode, the two friends continue to cope with life after the plane crash and their ever-growing responsibilities at their respective hospitals. As Meredith juggles taking care of Zola with a case that hits close to home, Cristina assists Dr. Thomas on a challenging heart surgery.

Cristina goes right back to working right after being discharged. Izzie isn't talking to Alex. Derek and Meredith treat a patient. George and Alex get stuck in an elevator.

In this Amelia-centric episode, Amelia engages in the surgery of a lifetime as a crowd of doctors look on from the gallery. With Stephanie by her side, she begins operating on Dr. Herman, but quickly realizes it's far more difficult than she anticipated. Meanwhile, Bailey becomes skeptical when Arizona takes on one of Herman’s cases.

Cristina and Burke continue to play Uncle until one of them gives in. Derek and Meredith are fighting over the reason for their sleepless nights. Meredith tries to talk to her father about his side of the story. There's tension between Alex and Addison. There is even more tension between Addison and Mark. Addison confides in Callie. Bailey wishes she didn't have to keep a secret from one of the interns. Callie rushes to be with George after she learns that his dad needs an emergency procedure. Izzie may have found 'some good to do' with her inheritance.

After a burn victim unexpectedly dies in the midst of a chaotic ER, the Chief and board member Jennings interrogate the residents to find the culprit, as all the Mercy West and Seattle Grace resident defends their actions in an effort to save their jobs.

In his new role as Chief, Derek restores the hospital lecture series, and Richard, Bailey and Callie present to the group pivotal surgical cases from their pasts Bailey reflects on her first days as a shy resident, Callie looks back on a polio case, and Richard recalls a case in which he and Ellis worked on a patient diagnosed with GRID, a virus later called AIDS.

One of Grey Sloan Memorial’s own is seriously injured, making the team reflect on what is truly important to them. Meanwhile, Nicole Herman pays a visit to Grey Sloan and talks to Arizona about an exciting opportunity.

The discord and chaos created by the hospital's new management team causes one physician to question his future at Seattle Grace. Meanwhile, the doctors and the interns must juggle several transplant surgeries at once, each coming with its own set of obstacles.

Cristina considers her future at the hospital; Amelia and Derek collaborate on a tough surgery involving conjoined twins; Jo takes on too many cases at once; Stephanie stumbles on the truth about Bailey's case.

In the first part of the two hour season finale, Izzie spends time with a fellow cancer patient and contemplates whether or not to undergo a risky surgery, as Mark is ready to take his relationship with Lexie to the next level and a patient makes Owen reassess his place at Seattle Grace.

The residents determine their future as they make their final decisions regarding post residency positions; Mark admits to Derek that he is torn between his love for Lexie and the fact that Julia can give him everything he's ever wanted; Ben plans something extra special for Bailey, but she is preoccupied with her work; and Arizona encourages her childhood friend, Nick, to have surgery. Meanwhile a couple on their third honeymoon come to the hospital complaining of mysterious symptoms.

After eight years of practice, the residents head to San Francisco for their oral boards; sparks fly between Catherine and Richard when they bump into each other at the hotel; Bailey intervenes after Owen and Teddy get into a heated argument about their young car crash patient; and Mark tries to recruit Lexie for one of his cases. Meanwhile, Alex feels guilty for being away from the hospital when Tommy's health begins to fail.

As the hospital spirals closer to financial ruin, Owen must make some tough decisions, which includes foregoing an expensive surgery that could save the life of a child. Meanwhile, Alex and Jo work together to save the life of an infant, and April asks Jackson for dating advice.

A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.

A traumatic car accident fills the ER. Izzie pushes the boundaries of her probation. Cristina has a crisis of conscience about her deceptive teamwork with Burke.

The doctors of Grey Sloan encounter a difficult case involving a dangerous patient. Meanwhile, Owen receives life-changing news that pushes Amelia to step up to support him, and Alex attends a medical conference after making a shocking discovery.

After a roller coaster car falls off the track at the county fair, the doctors at Grey Sloan tend to patients who spark memories about ghosts from their past. The series 300th episode!

The Grey Sloan Memorial Hospital doctors are faced with the devastation left by the storm. A giant mudslide in Seattle injures a group of first responders and citizens, causing the already short handed ER to spring into action. Meanwhile, Meredith is faced with a tough decision that will affect the life of a loved one, Callie is rocked by the reality of Arizona’s infidelity, and Richard’s life is in extreme danger.

Cristina Yang has little sympathy for Constance Ferguson (special guest star Rosanna Arquette), a prison inmate who jeopardizes her health just to get out of solitary confinement. Meanwhile the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges, Izzie's anger at Alex reaches boiling point, and Dr. Addison Shepherd decides to teach Izzie a very painful lesson.

Meredith discovers that Derek has a problem sleeping while her father comes to visit the hospital. George's father is moving from one surgery to another. A patient named Heather checks into the hospital. Heather is 17 and has a nasty attitude that results from her medical condition and all the surgeries it has required her to have. Izzie has an emotional breakdown when she tries to hand over something very important to her. George's family comes to visit to celebrate his father's surgery. Cristina and Burke are playing Uncle.

Jo finally faces her estranged, abusive husband Paul Stadler, while Grey Sloan continues to work with the FBI after a hacker has compromised the hospital’s computer system.

As Cristina tries to recover, she proves to be a very difficult patient, and a visit from her mother doesn't improve her demeanor any. And Meredith's mother, Dr. Ellis Grey, has the hospital staff running in circles.

After the Chief announces his retirement, rumors begin to circulate on his departure and successor. Mark is determined to leave Seattle for good but Meredith accidentally has him stay after letting him know of the open Chief position. Derek is angry at Meredith for causing Mark to stay in Seattle, but soon realizes that she is not the reason he is really angry. The attending physicians at Seattle Grace Hospital fight to get Richard's attention, but he expresses his disappointment. He also displays his lack of support in Bailey's plan to create a free medical clinic, but she ultimately goes through with her plan when Izzie offers to spend her entire 8.7 million dollar inheritance on the project. George, devastated after his father's death, uses sex to overcome his grief, and eventually proposes to Callie. Cristina and Burke still don't speak to each other, but he breaks the agreement when he proposes to her. Richard endeavors to reunite with his wife, Adele, and decides to retire, only to come home and find his wife with another man.

Meredith Grey and the team of doctors at Grey Sloan Memorial are faced with life-or-death decisions on a daily basis. They seek comfort from one another, and, at times, more than just friendship. Together they discover that neither medicine nor relationships can be defined in black and white.

Meredith faces the medical board as her future as a doctor remains uncertain, and she’s forced to reckon with her past in some challenging ways. Meanwhile, the interns are put to the test as they are each vying to be the most successful on their respective cases in the absence of some of the attendings.

Meredith works furiously to save a paramedic trapped in an ambulance; Lexie holds the life of a patient in her hands; Derek must rely on a nurse to save a patient; Bailey struggles to balance her personal life with her work.

Cristina meets Burke's parents, the interns try to get Izzie's job back, and Addison takes a day off, a surgical patient may be living her last day. Some of the interns want to know why Bailey won't talk to Izzie. Meredith tries to decide between Derek and Finn and comes to a decision somewhat. Webber finds out that Callie has been living in the hospital and he confronts her about it.

All eyes are on Derek as he is set to perform his first surgery after his breakdown; attention is also set on Izzie, whose medical condition requires her to undergo a difficult surgery; and Owen has another PTSD episode that injures Cristina and traumatizes both of them, throwing the future of their relationship into question.

An ambulance crash endangers the lives of the paramedics involved, as Meredith and the Chief work on-site to save them, Bailey treats a patient who refuses her help, and Ava returns for Alex and meets his other girlfriend in the process.

Derek's confidence is shaken like never before as he faces off with Addison over what course is best for their dying pregnant patient; Cristina calls the abilities of a renown surgeon into question after she botches a standard procedure; and Bailey, who has decided to pursue a fellowship in Pediatrics, is appalled by the Chief's less-than-stellar recommendation letter.

Dorie Russell is waiting for quintuplets, all 5 girls. Her husband seems more concerned than she is but she is set to bring her babies to their term of 36 weeks. All the departments are on call for the quintuplets as three of them have developped problems of different kinds. Meredith last night's stand shows up at the hospital with priapism and they need to call Derek Sheperd for a consult which puts Meredith in a very embarassing position. Alex and Derek must take care of a patient who has a tumor inducing thirst as a side effect. On the love side, Alex and Izzie are having some slight sexual problems, while Meredith goes on adding one night stands and Cristina is thrown off course by being "keyed."

The hospital staff is left to deal with the aftermath of George's passing. Hitting the staff hard, they all find unique ways to get through the various stages of grief. George's mom returns, faced with the difficult task of deciding what to do with his organs.

Shawn Sullivan, a car salesman who just had surgery, wants to get back to his routine so he doesn't lose his renown. Addison works with a pregnant woman named Rebecca who may need a C-section and Addison doubts her medical skills. Rebecca wants to have the baby naturally. Derek and Mark's opinions clash when the try to decide the course of treatment for a burn victim. Izzie gets surprised. Cristina pushes Burke to get better faster.

A generous 25 million donation is offered to Seattle Grace by the parents of Arizonas 10-year-old patient, she finds herself in a conflict of interest when his condition worsens. Cristina tests her boundaries with Owen at the hospital. Alex is left with all of Izzies hospital bills to contend with.

Izzie tries to get George to find the courage to ask Meredith out. All of the interns are in awe when a woman comes in with a record breaking tumor, but it is so far advanced that the woman's prognosis is not good. Now that Bailey knows about Meredith and Derek's affair, their jobs are in jeopardy, and she advises Meredith to end it. Meanwhile, Cristina and Burke's secret relationship is also getting more complicated...

Bailey puts her wedding day on hold and continues her efforts to save Adele's life, Cristina and Owen remain undecided about their pending divorce, while Arizona and Callie try to get their spark back. Meanwhile, the hospital becomes inundated with a group of bikers after a horrible accident.

Meredith must make an important choice about which path she wants to follow to determine the future of her love life. While she considers her future she and others have flashbacks of their pasts. Cristina spends time with Burke while he recovers. Webber and Adele have a conversation after he spends the night at the hospital. Everyone attempts to deal with Izzie's choice to quit. George seeks relationship advice from Derek.

Meredith and Izzie take up knitting. Derek operates on Andrew, a spelling bee champ with a serious head injury. Bailey gets in on Andrew's surgery because she's worried that her coworkers won't recognize her Nazi-status now that she's a mother. Addison's patient has an unborn baby with medical issues. After Alex fails to bite his tongue when a terminal patient routinely lies to her daughter about her health he gets a lesson in bedside manners from Burke. George also begins to overstay his welcome at Burke's apartment after Callie visits him. Meredith has more confusing and uncomfortable encounters with members of her family. One of the female doctors meets a veterinarian named Finn. Izzie flirts with Denny and they play more naughty-Scrabble. Meredith, Derek, and Addison sarcastically take another small stab at their friendships.

Meredith is brutally attacked by a patient, and Penny is the one who discovers her. The doctors of Grey Sloan Memorial rush to stabilize Meredith and remain by her side in the harrowing aftermath.

Owen stresses teamwork and moves his leadership role over to the baseball field when he signs the doctors up for a baseball league, pitting them against their biggest competition, Seattle Presbyterian; Lexie tries to hide her jealous rage when she sees Mark with a new woman, but her emotions get the better of her; Alex fights to keep Zola at Seattle Grace after it is suggested that she be moved to another hospital due to a conflict of interest with Meredith and Derek; and Richard scolds Meredith and Bailey for their feud

In this flashback episode, return to the site of the plane crash and watch as each doctor tries to cope with the heartache and injuries caused by the crash. Meanwhile, back at Seattle Grace, everyone struggles to find a bit of normalcy amidst the chaos.

Picks up where the last episode left off. Meredith attempts to work with Addison Shepard. George is pimped out to relay the hospital gossip back to Webber. Meredith and Cristina relate at Emerald City Bar about what dating their respective attendings is like. Cristina ponders her relationship with Burke while trying to make a decision. Meredith is devastated by the latest blow to her love life. Meanwhile, Joe the bartender collapses.

The doctors reach out to Bailey but she continues to shut everyone out; after an incident with Ethan's grandmother, Owen fears the child could end up in foster care. A new craniofacial specialist arrives at Grey Sloan Memorial Hospital to work on a young patient. Meanwhile, a magician's assistant is rushed into the ER after a magic trick goes terribly wrong.

A young boy is admitted to Grey Sloan Memorial and his case has a profound impact on the doctors. Meanwhile, April is faced with a surprising patient, and Jo continues to deal with her estranged husband.

All the nurses at Seattle Grace Hospital go on strike, leaving the doctors to fend for themselves. George refuses to cross the picket line and finally joins the nurses on their strike while Alex, Cristina, Izzie and Meredith meets Bailey's stand-in: Dr. Cindy Aaron, the complete opposite of Miranda Bailey. Izzie agrees to work on a difficult pregnancy case with Addison, while Cristina and Alex are in the pit attending to a young married woman with a real bad case of rash. Meredith happens on an old woman that she needs to intubate and then learns she was DNR.

Meredith, looking to prove she is Chief Resident material, learns that anything and everything can happen in an hour's time when she steps up to run the ER for a night; meanwhile, Bailey sneaks off with Eli and gets into a little mischief, and everyone is surprised when the Chief's wife, Adele, shows up as one of the ER patients.

Cristina enlists Meredith to help her prepare an acceptance speech for her possible Harper Avery win and while Owen offers to attend the ceremony with her, she insists on going alone. Meanwhile, Derek feels overwhelmed between his responsibilities at home and at the hospital. April and Jackson come to a disagreement on children and religion, and Callie and Arizona try to reconnect in their marriage.

Cristina, Izzie and Meredith take care of Shane, a man who appears to be crazy and claims that he is pregnant. Shane's case induces a spreading fascination among the staff. George relates to a patient's husband.

Meet Meredith Grey. Daughter of famous surgeon Ellis Grey and currently recovering from a one-night stand. She shoos away her evening's companion, saying she'll be late for her first day of work. She is a first year intern at Seattle Grace Hospital and is working alongside some colorful characters. Cristina Yang is a highly competitive Stanford graduate who befriends Meredith. George O'Malley is a quirky warm hearted man who learns a lesson or two on his first day. Izzie Stevens is a former model who doesn't get any special treatment on her first day. And Alex Karev is an arrogant jerk who misdiagnoses a patient on his first shift. Overseeing them is Miranda Bailey, (not-so-) affectionately dubbed 'The Nazi'. Meredith also gets a surprise when she realizes that her friend from the night before is a co-worker, and even worse, her boss.

The blood shortage at Grey Sloan Memorial continues. Meanwhile, Meredith makes a risky decision regarding a patient, and Owen’s actions to help his fellow veterans come to light.

George's father has a serious heart problem that requires surgery and George chooses Burke to do the procedure. Burke doubts himself because he knows the pressure this kind of surgery will put on him, but Cristina believes the team can handle it. Derek works with Meredith on being a couple again and tries work with Addison on more civil terms. A patient has had mutiple plastic surgeries so that his girlfriend will like him more. A mom wants her daughter's babysitter fired, after she is brought in with multiple injuries, but the girl likes the babysitter more than her mother.

Recent events strain Burke and Cristina's relationship. Mark and Derek must work together when two close-knit brothers seek medical help. One of Meredith's half sisters is admitted to the hospital.

A hacker compromises the hospital’s computer system, causing monitors, phones, labs and patient files to all go down. As technology fails them, Bailey attempts to keep the peace but chaos erupts and the doctors are forced to get creative in their methods to treat the patients.

Derek decides to quit after learning that more of his patients have died than survived; Izzie's interns make an unsettling discovery about "Patient X."

Callie makes a decision about her relationship; the doctors receive devastating news.

Secrets from Ellis Grey’s past come to light when Meredith watches old videos and reads through her mother’s journals. Meanwhile, Maggie rocks the hospital with an unexpected announcement; Alex gets new responsibilities and Callie focuses her attention on the Veterans’ project.

The surgical staff tries to be optimistic as a young woman clings to life after a brutal attack. Meanwhile Meredith puts her career on the line to save a newborn in the hospital nursery, and the other interns learn that it takes more than just medical knowledge to be good at their jobs.

The residents try their hardest to impress surgical great Catherine Avery-who also happens to be Jackson's mother-when she arrives at Seattle Grace to perform a groundbreaking transplant surgery; Arizona and Alex find their hands tied with a confidentiality issue when a familiar patient comes into the ER; meanwhile, a love-struck Teddy throws a dinner party for the couples, and Bailey makes a decision regarding her love life

Derek learns one of Addison's secrets. Bailey talks about motherhood and depression to a mother who is set to have cancer surgery and who seems to not care about any decisions concerning the future. A resident is fiercely questioned about the death of a male patient. An ex-couple meet before lunch and get stuck - Meredith and Addison work on their case. Things get awkward when the ex-couple's daughter, Michelle, arrives at the hospital.

A gas tanker explodes on a Seattle highway, causing multiple injuries, including paramedic Matthew. Meredith and Jo help a frantic mother whose child is suffering from a mysterious illness. Owen bonds with a young boy whose parents are in critical condition. Meanwhile true colors are revealed when Alex is forced to work with Jo's boyfriend on an ailing patient.

The doctors of Seattle Grace are faced with the aftermath of last season's plane crash. As they try to move on with their lives, they must learn to adapt to the changes, cope with their losses and move forward with their relationships and careers.

As she endures aggressive treatment for her cancer, Izzie throws herself into planning Derek and Meredith's wedding.

A stampede at a comic book convention leads to an influx of colorful characters in the ER; Mark continues to make life difficult for Jackson; Ben returns and realizes Bailey has moved on.

The doctors are faced with the consequences of the events at April's wedding. Alex reacts to the news about his father. Callie and Arizona make a decision about their relationship.

The staff tries to prevent a patient from getting an elective surgery. Cristina tries to help Preston cope with the after effects of his surgery. A patient bails on their surgery. Someone goes to a bed-and breakfast. Alex deals with a patient who has had a high amount of injuries in the past. A man undergoes surgery. Before the surgery his wife was only somewhat supportive, but the results may be too much for her to handle. Izzie tries to go back to the hospital for the first time since Denny died. One child's constant visits are noted by a nurse. Two foster patients are met with suspicions of child abuse. George and Callie's relationship moves forward.

Derek's mother, Carolyn, makes a surprise visit to Seattle and meets Meredith for the first time, as Mark tries to conceal his relationship with Lexie from her as well; meanwhile, death row inmate William wishes to donate his organs to Bailey and Arizona's patient, as Owen and Cristina try to go on their first date.

The doctors split into teams for a risky surgery involving conjoined twins; Bailey recruits Meredith to be a buffer between her and Ben when he puts pressure on moving their relationship to a more serious level; Richard teaches Alex a tough lesson in the OR; meanwhile Teddy questions Cristina about what exactly happened to Henry during his surgery.

News of Meredith and Derek's unsteady relationship raises a red flag for Zola's adoption counselor; Alex quickly realizes that he has become the outcast of the group after ratting out Meredith; and Cristina makes a tough decision regarding her unexpected pregnancy. Also, Chief Webber brings Henry in for a last minute surgery, alarming Teddy. This is an historic episode that finally crosses a long-standing barrier.

As preparations continue for Meredith and Derek's wedding, Izzie receives a surprise hospital visit from her handful-of-a-mother, Robbie. Meanwhile, a newly sober Thatcher visits his daughters, Meredith and Lexie, in order to make amends, and the Chief and Meredith bitterly fight over a controversial medical case.

The doctors are up to their necks in their usual levels of drama. Meredith is dealing with the backlash of sleeping with George, George and Burke are bonding in ways that bother and creep out Cristina, Cristina gets stuck on diaper duty, Bailey gets involved in a case even though she's still supposed to be on maternity leave, Addison and Derek have a talk, and Izzie is still flaking on Alex for Denny Duquette, the heart patient who didn't get a heart. In the patients-of-the-week department we've got a very pregnant woman, a hockey player who desires medically unnessasary amputation, and a woman with a fork in her neck who happens to be dying and has a struggling marriage.

Believing he is going to jail tomorrow, Alex makes a big decision about his future. While the hospital is overrun with victims of a building collapse, Richard demands answers from Bailey about Eliza’s presence at Grey Sloan.

It's Thanksgiving at Seattle Grace Hospital but the holiday's festivites are less than in order. Meredith and Derek try to counsel a family after their relative has had a seriously traumatic accident.

While George is feeling a little less masculine because of the way Izzie and Meredith have been treating him (like a sister), Izzie is assigned to a patient about to loose all of his masculinity. Cristina, true to her competitive spirit, shows up early and assigns herself to an ill woman, who happens to have been Meredith's moms scrub nurse. Alex, meanwhile, is busying himself copying and pasting pictures of Izzie's racy magazine spread all over the interns' locker room. And while Meredith is trying to cope with her mother's Alzheimer's, Derek treats a patient who has managed to get nails stuck in his head.

Addison's patient is a Catholic mother of seven. Addison gets in trouble after learning that the patient's husband won't use contraceptives. Derek treats a divorce attorney who asks if Derek is in need of her services. While Izzie and George are talking about their personal lives they "overhear" part of Derek's conversation with the divorce attorney who calls herself one of Seattle's best. Alex gets in trouble with Addison yet again for not being able to keep his mouth shut when other people think he should. A legendary jazz musician refuses to see medical reason. The musician is Burke's musical hero. Finn makes Meredith breakfast.

News of Meredith's dishonesty in the clinical trial comes to light, leading to unanticipated consequences for her and others; Cristina finds herself in a compromising situation, which forces her to decide between her career and her relationship; Owen posts his decision for Chief Resident, and Teddy makes a surprising choice regarding her love life -- and her future.

The doctors work on a Jane Doe, who turns out to be the subject of a case that gained national interest; Cristina proves to be the highest in demand as the residents begin their interviews for post-residency positions at prospective hospitals; and Richard is faced with an unsettling realization when he visits Adele at Rose Ridge.

As Callie and Arizona's wedding approaches, the couple quickly realize that the day they've been looking forward to is not turning out the way they'd envisioned. Meanwhile Alex continues to make the other residents jealous as he appears to be the top contender for Chief Resident, Meredith and Derek make a decision that will change their lives forever, and Dr. Perkins presents Teddy with a very tempting proposition.

The doctors become nostalgic when George O'Malley's mother, Louise, returns to Seattle Grace for medical help after a botched surgery at a neighboring hospital; the residents are inspired by a medical miracle when they witness a harvested heart that continues to beat outside the body; a new pediatric fellow excites Arizona and makes Alex feel threatened; Jackson lets his suspicions about Mark and Lexie interfere with his work; and Henry and Teddy have their first marital fight when he expresses interest in pursuing medical school

Callie and Arizona are at odds over Sofia’s future, and Stephanie questions the status of her relationship with Kyle. Meanwhile, Alex and April work on a pregnant teen that is readmitted to Grey Sloan Memorial.

The race between the attending physicians for the Chief of Surgery position heats up after a new competitor enters the fray. They soon realize that the new surgeon, Colin Marlow, was Cristina's professor in medical school and they used to have a long-term relationship. He begins to lie to Burke in order to protect her secret, but is soon faced with the realization that their relationship is on the rocks. George finds out that Callie's family is rich, but she had previously hidden the fact in order to find out whether George loves her for who she really is. Derek treats his former colleague from New York, and forces her to have surgery for brain cancer in order to save her future, no matter what the post-surgery risks are. Alex continues to work with Jane Doe, whose memory doesn't seem to come back. He moves in with Meredith and they have a dinner with her father and stepmother. She seems to connect with Susan, but her relationship with Thatcher seems to be irreparable. Izzie wakes up, realizing that she has slept with George while they were both drunk.

Richard is desperate for Derek and Meredith to accept Adele into their Alzheimer's trial, but will Adele stand in her own way? Meanwhile Mark and Arizona have conflicting ideas of the kind of baby shower Callie wants, Teddy is freaked out when Henry has another health complication -- leaving them both a little exposed -- and the competitiveness amongst the residents for the Chief Resident position is amplified when Richard receives the green light for his diabetes clinical trial.

Seattle is hit by a huge wind storm and Grey Sloan becomes inundated with patients. Alex and Jo are stuck at home and decide to make the best of it by having a second honeymoon, while Meredith confronts Richard about getting his life back on track. The winter finale.

As the hospital continues to make positive changes under the new management, the doctors begin to realize that owning a hospital comes with its own set of problems and responsibilities. Meanwhile, Meredith worries about the wellbeing of her unborn baby, Callie and Arizona try to get the spark back in their relationship, and Alex gives Jo‘s new boyfriend a run for his money.

The fifth-year residents return for the first day of a year that will make or break their careers: Meredith faces the consequences of tampering with Derek's clinical trial and is terminated at the hospital; April tries to step up to the plate as Chief Resident in the wake of a giant sinkhole in the middle of Seattle; and Cristina and Owen are still at odds over their drastically different feelings for their unborn child.

The interns finally take their first year medical exams, the biggest test of their careers, and one of them is ill-prepared. Callie grows more suspicious of George and Izzie. The doctors treat a patient named Dale. Three mountain climbers are treated. Cristina works on her vows. Adele wants Addison to keep a secret from Richard.

Link tries to convince Amelia to take it easy during the final stage of her pregnancy. Hayes asks Meredith a surprising question, and Owen makes a shocking discovery.

Meredith and Nathan have to confront their feelings when they are are stuck sitting next to each other on a plane.

Meredith and George are experiencing morning-after tension at home and at work and it has the rest of the doctors wondering what's up. Derek and Addison are experiencing their own version of morning-after tension as a result of Mark's visit to Seattle. Bailey, returning the favor that was done for her during the Code Black situation, must treat Addison for a specific feminine problem. Izzie and Alex are making headway in their relationship until Denny Duquette comes back. Soon Alex is not-so-oddly jealous of the attention Izzie is showing to Denny. Someone finds comfort in confiding in a patient who is going through an ordeal of his own. Burke deals with a patient and gets to observe the patient's unstable relationship with his fiancée.

A lion breaks loose in Seattle, leaving a couple's lives and relationship at risk; Lexie overhears Mark's discussion about moving in with Julia; Teddy begins to take steps towards coming to terms with Henry's death; Callie grills Arizona on her past lovers; and Alex requests to be taken off Morgan's preemie case when she becomes too dependent on him. Meanwhile, Meredith tries to be a support for Cristina as the tension between her and Owen hits a boiling point.

Derek and Meredith try (unsuccessfully) to be discreet as they spend the night together at Meredith's house, but their haggard appearance speaks volumes to everyone - including Bailey, who warns Meredith to end the relationship. Meanwhile George suspects an anesthesiologist of drinking on the job but is reluctant to speak up about it, Alex treats a former competitor who now finds honor in self-mutilation, Izzie has to deal with a patient who won't let go of his girlfriend - literally, and Cristina seems to be battling a case of the flu.

The holiday season has started but not everyone is in a festive mood. This is Alex's last day in the hospital unless he passes his boards practical exam the next day, thus everyone helps him to review so that he succeeds. However, Izzie is not happy about the others helping him and Meredith has to remind her of the true spirit of the Christmas holiday. Justin is in need of a new heart. One is available but he does not want it because he does not believe Santa gave it to him as his mother said. Cristina and Burke, both handling Justin's case, have opposing views on the matter due to their different stances on religion. Despite a reconciliation with his wife, Derek isn't in a festive mood. George has a simple case of a woman who has a bleeding ulcer, he realizes that the ulcer is caused by her entourage but fails to keep them away, with the consequence that it perforates.

After a series of deaths at the hospital some of the staff become very superstitious. Izzie worries about Denny and gets confronted by Alex. A patient with OCD drives Cristina crazy. Derek and Addison discuss their relationships with Meredith. Richard treats a friend from 17 years ago who reveals a secret about a dark time in his past that involves Ellis. George gets an earful about the women he's not talking to. Burke and Cristina argue about kicking George out.

As part of their training, Seattle Grace's residents are put in charge; the attending surgeons compete for a million-dollar grant.

After an anonymous complaint is issued by one of their own, the hospital implements a non-fraternizing policy causing the couples to panic. Meanwhile, Emma and Owen talk about the future, Cristina and Meredith enjoy a little girl time, and Richard enlists the residents to help research a rare cancer case.

Harper Avery arrives at Grey Sloan, putting Bailey on edge. A familiar face from Meredith’s past returns as a patient, and Amelia tries to manage a secret.

Jackson is given the daunting task of delivering disappointing news to the doctors. Meanwhile, Derek's sister Amelia drops by for a surprise visit, Richard surprises Catherine in Boston and when Bailey gets frustrated by the slow pace of her research, she makes a risky decision.

Meredith struggles to come up with a new plan for Owen’s sister. Jo makes a surprising choice regarding Alex, and Andrew’s sister’s controversial research leads to a shocking discovery.

Cristina won't let herself get excited when she is nominated for a Harper Avery award; Alex thinks about making a change; Callie and Derek work with a machine that recognizes emotions.

When an unexpected malpractice suit turns Callie's world upside down, her supportive father arrives and shares an interesting secret with her. Meanwhile, through flashbacks, we learn some surprising details about Callie and Arizona's marriage.

Arizona has a bad day which escalates when she advises one of Callie's patients on a potential double amputation. Derek goes back on a promise to Callie, and Jo and Stephanie come across an abandoned baby outside the hospital. Meanwhile, the doctors deal with the repercussions of the non-fraternization rule, which include meetings with HR and one doctor's suspension.

As the doctors continue with their lawsuit, they’re forced to confront the realities of their injuries. Meanwhile, Bailey tricks Arizona into helping her with a pediatric case, and Cristina tries to find normalcy in her new environment.

After several discussions with Dr. Herman, April and Jackson must face their situation head on and make a difficult decision regarding their unborn child. Catherine arrives in Seattle and bumps into Richard at the hospital. Meanwhile, Meredith tries to find someone to take care of the kids so she can visit Derek for the weekend, and Amelia shows Stephanie some tough love when they work together on a case

Alex is offended when Izzie talks about how great a man Alex is to Meredith. Derek is stabbed with the scalpel in the palm of his hand by Rose, while the Chief is stunned over Mercy West's increase in the number of patients, a deadly ice storm ravages Seattle.

Derek takes Cristina out on a fishing trip; Teddy tries to help a patient who lacks the proper insurance to seek medical treatment.

After a heart-wrenching loss, Teddy struggles to cope and it triggers memories of her past. When Owen brings her home, she must face some long-standing truths. Meanwhile, Amelia tries to help the situation by encouraging Owen to accept and forgive Teddy.

Bailey and Ben face a huge, life-altering decision, while Meredith and several of the doctors reflect on the past.

A difficult surgery brings back pivotal memories for Meredith, Richard, Owen and Stephanie, as they work together to save a life.

Simone is met with a life-changing decision upon the return of someone from her past. Blue shadows Maggie on a risky procedure, while Jo and Link tend to a pregnant woman. At the intern house, Lucas and Mika throw a party filled with surprises.

Nick whisks Meredith away to his Minnesota cabin for a romantic weekend, leaving Winston and Maggie to care for Meredith’s children. Meanwhile, Amelia and Kai grow closer.

The evolution of April and Jackson’s relationship is revealed through a series of flashbacks dating back to when they first met. Simultaneously, we follow the years-long progress of one of Jackson’s patients.

Jackson pays a visit to his father that helps set him on the right path.

In a flashback to Iraq in 2007, the events leading up to Megan’s kidnapping are revealed. In present day, Owen and Megan hash out old wounds.

Maggie is preoccupied with Winston while trying to treat a patient wounded in the Seattle protests. Meanwhile, Levi is tested by an emergency, and the doctors struggle to treat a patient who doesn't believe in COVID.

Richard continues to navigate his health. Meanwhile, Meredith and Nick are visited by Nick's estranged sister from Boston.

Cristina imagines the two routes her life can take based on one decision she makes. Meanwhile one of the hospital’s patients decides whether or not to live.

Bailey and Blue are forced to confront the emotional costs of experimental care. Meanwhile, Owen, Teddy, Simone and Dani help out at a busy rural hospital, and Richard attempts to spread information about early prostate screenings to the community.

Jackson creates an uncomfortable situation when he invites new girlfriend, Vic, to what he thinks is Richard and Catherine’s anniversary celebration, only to discover the dinner was called for different reasons. Elsewhere, Levi brings Nico on a trip to visit an ailing family member.

It’s Maggie’s last day. Amelia’s relationship with Kai is tested, and Ben worries as Bailey’s doxing intensifies.

Teddy makes a challenging decision. Meanwhile, Maggie and Winston aren’t on speaking terms, and Link leans on Jo for emotional support as he preps for a surgery on a well-known athlete. Simone and Lucas are surprised by an unlikely visitor.

Bailey welcomes a renowned surgeon, whom she greatly admires, to Grey Sloan to help on a challenging case. Meanwhile, Teddy, Owen, Jules and Ben team up to save the life of a patient who has been impaled by an ice pick.

Amelia and Simone attempt to perform a high-stakes and groundbreaking brain surgery. Teddy and Bailey attend a medical conference and run into Dr. Cass Beckman. Meanwhile, Jo struggles with her irritation toward a younger OB-GYN.

A cataclysmic event leaves the doctors shaken; Callie, on the verge of a life-changing moment, starts imagining about the hospital and her friends.

Meredith seeks advice from Amelia. Meanwhile, Richard is reenergized as he takes teaching to a new level at the hospital, and Winston treats a patient suffering from kidney failure.

It's Thanksgiving, and while Meredith faces travel complications due to the weather, Nick steps in to help in more ways than one; Richard and Bailey seek out emergency surgeries; Amelia and Link reconnect.

A window washer’s platform crashes through a hospital window, testing the Grey Sloan team’s limits. Meanwhile, Blue and Simone clash over their living arrangements, and Lucas strives to impress Catherine while on her service.

After firing some of Grey Sloan's best, Catherine continues to interfere with Meredith and Amelia's research. Accidents at a climate change protest bring unique cases to the hospital, and Bailey encounters a blast from the past.

It’s Meredith’s last day at Grey Sloan Memorial and the doctors plan a goodbye surprise, while Nick confronts her about the future of their relationship. Elsewhere, the interns compete to scrub in on Maggie and Winston’s groundbreaking partial heart transplant procedure, and Richard asks Teddy an important question.

Following a difficult case, the team faces the complexities of medical ethics. Meanwhile, Bailey continues to navigate her working relationship with Ben, while a group of college students on a scavenger hunt causes chaos around the hospital.

Owen and Teddy have the day off but encounter an injured civilian. Monica enlists Amelia's help with an operation on a young patient. The interns complete their procedure logs, allowing them back into the OR.

Bailey faces an unhappy Catherine who is facing audits for several of her Foundation hospitals. Meanwhile, Addison is back at Grey Sloan; tensions rise between Meredith and Richard, and Owen returns to work.

As the city of Seattle revels at the Phoenix Fair celebrating the city’s rebirth post-COVID, the Grey Sloan doctors treat a patient who encounters illegal fireworks. Meanwhile, Bailey has her sights set on hiring new doctors, but she’s having trouble finding viable options. Owen and Teddy attempt to take the next step in their engagement, and Meredith has a surprising opportunity when she meets a dynamic doctor from her mother‘s past. The crossover starts on Station 19 S05E01 Phoenix from the Flame (I).

The interns juggle a bizarre trauma, while a complex breast reconstruction forces Meredith into a tense partnership.

Meredith and Catherine continue to disagree, and Meredith confides in Bailey for support. Richard, Winston and Lucas spend the day outside of the hospital, and Blue deals with a relationship from his past. Levi meets the new hospital chaplain.

Meredith and Amelia prepare a funding proposal for their Alzheimer’s research. Meanwhile, Teddy and Owen hit a breaking point in their marriage, while Jules has an awkward encounter with Dr. Beltran.

Richard recruits Meredith and Bailey to help him launch a new program. Meanwhile, Addison’s patient has complications from a procedure, and Jo helps a woman who goes into premature labor.

Dr. Hamilton takes his frustrations out on Meredith, so Nick gives her a chance to blow off steam by scrubbing in on a surgery. Back in Seattle, Link and Jo take their kids to a fairytale theater performance that goes wrong. Bailey and Dr. Lin attend a recruitment fair in hopes of attracting more doctors to Grey Sloan but find themselves ill-prepared.

Catherine returns to Grey Sloan for a surgical case that makes Lucas and Blue queasy. Amelia treats a possible cancer patient with a family that’s a little too supportive. Owen takes his medical future into his own hands, much to Teddy’s surprise.

Addison Montgomery returns to Grey Sloan, seeking assistance with a patient with a neurological condition. Bailey joins Owen and Blue on a paramedic ride-along.

Bailey and Owen join forces to save a tumor patient, while Richard faces an internal battle. Meanwhile, Jules struggles with her feelings for Winston.

Levi gets accepted into the vaccine trial. Meanwhile, Amelia and Owen treat a car crash patient, and Hayes and Jo are met with Luna’s legal guardian.

During a high-stress day at Grey Sloan Memorial, the fates of a patient in critical condition and a helicopter-bound medical team hang in the balance. Teddy and Owen work on their marriage, while Bailey, Blue and Link treat a hospital employee.

An unexpectedly complex case brings back painful memories for Simone. Jules and Blue make a high-stakes bet on who can finish their procedure log first. Richard suspects Winston is avoiding him.

Upon realizing that Owen and Amelia have been seeing each other behind her back, Meredith comes down hard on her sister-in-law causing Amelia to rethink things. Meanwhile, Catherine springs into action when a man is brought into the hospital after his wife seeks revenge on his cheating ways.

Bailey tells the interns they must complete dozens of basic procedures before being allowed back in surgery; things are awkward between Simone and Lucas; Amelia comes up with a solution to a complicated surgery.

Schmitt must face the Morbidity and Mortality conference. Meanwhile, Meredith convinces Nick to scrub in on a surgery in Seattle, and Jo faces her feelings.

The aftermath of the convenience store shooting brings chaos to Grey Sloan. Ben hits a wall with his new emergency preparedness plan. Romantic tensions surface for Owen, while Amelia and Winston disagree over the surgical plan for a young patient.

Bailey and Addison take a road trip to volunteer at a family planning center, but a patient’s ectopic pregnancy leads to complications. Elsewhere, the interns play detective about Lucas’ relationship with Amelia, and Meredith catches up with Jackson on a trip to Boston.

It’s Halloween night at Grey Sloan Memorial. Meredith and Nick try to spend some alone time together; Levi is stressed due to overworking, and Winston and Owen have the interns practice trauma training on a real cadaver.

Richard preps to present his PATH pen at the LA Surgical Innovation Conference but becomes distracted by his issues with Catherine. Maggie and Teddy run into people from their past at the same conference, while Hayes relives moments from when he met his late wife.

A small plane crash in Seattle causes multiple casualties and brings back horrible memories for the doctors, especially Meredith and Arizona. Meanwhile, friction between Owen and Amelia makes for an uncomfortable working situation for Stephanie.

Richard and Teddy make an exciting announcement. Jules and Blue butt heads over Maxine’s care while Lucas helps an artist decide on a risky procedure. Jo and Mika tend to Sam as Simone faces a life-changing decision.

Mika and Teddy receive a patient from a nearby penitentiary. Catherine pushes back on Link and Monica's treatment plan for a VIP. Bailey tries to integrate wellness into the residency program.

A former patient of Link’s, Simon, is in the ER with his pregnant wife; and Bailey receives an offer from Nick.

Meredith rethinks her plans. The interns are on thin ice following a patient's death. Simone and Lucas are immediately tested in an emergency. Richard confides in Bailey. Teddy's fate is revealed.

DeLuca can’t figure out what’s going on with his incurable patient Suzanne and he turns to a diagnostics genius, Dr. Riley from UCSF, for help. Bailey checks in on Joey, a foster kid that Ben brought into Grey Sloan. Meanwhile, Amelia is getting the results of her paternity test and Jo confronts her about how she is treating Link.

The Grey Sloan doctors spring into action after an explosion rocks Seattle, with the incoming trauma hitting close to home. Owen experiences PTSD after he hears the explosion, while his sister Megan enlists help from Winston and Hayes in confidence. In Minnesota, Meredith and Amelia meet up with a familiar face who assists in their study. The crossover starts on Station 19 S05E05 Things We Lost in the Fire (I).

Winston and Ben fight to save Jo's life, while Teddy supports Link. Owen and Jules battle to save a young man, and Lucas forms an unexpected bond with a patient.

A high-risk lung transplant pushes the surgical team to their limits. Meanwhile, Bailey juggles a trauma patient whose treatment hangs in the balance.

Addison makes a special appearance at Grey Sloan to welcome Bailey’s new OB/GYN trainees. Maggie’s lung transplant is derailed, and Nick bonds with Lucas — before the day takes a shocking turn.

Just as Amelia comes to a realization, Teddy encourages her and Meredith to speed up their Alzheimer's research over fear of Catherine finding out. Mika finds herself caught in the middle of Link and Jo; meanwhile, Lucas receives bad news.

While Richard ponders his surgical abilities, Jo is charmed by her patient’s brother. Elsewhere, Megan makes sure Teddy and Owen talk out their differences, and a pet python causes an uproar.

Meredith and Amelia work to secure funds for their research while Amelia finds herself at odds with a new attending. Levi runs into someone from his past, and Owen gives Winston advice. Lucas ditches Mika, forcing her to treat a patient alone.

With Levi’s help, a patient celebrates a milestone. Jo processes a difficult diagnosis, and Maggie and Winston decide their future.

A bull rider shows up at Grey Sloan with severe injuries, forcing Maggie, Amelia, Owen and Blue to examine their own biases. Elsewhere, Simone can’t find anyone to be her maid of honor, and Mika takes drastic measures to pay down her student debt.

Simone's wedding day arrives as Jo and Link's relationship hits a major turning point.

Mika struggles with a life-altering personal matter. Meanwhile, Bailey and Ben navigate their personal and professional roles, while Levi finds a connection in an unlikely place. Jo and Link get surprising news.

The Grey Sloan doctors are stuck in the middle of a fight between a newlywed couple who are injured in a car accident and brought to the hospital for treatment. Meanwhile, Jackson’s generosity with COVID-positive patients goes a bit too far, and Hayes works to rebuild Maggie’s confidence and convince her to perform an extremely risky heart surgery.

When Teddy's patient seeks to end treatment and her life, she turns to Hunt for help. The situation triggers Hunt's memories of his life at war and his past relationship with Teddy. Meanwhile, Callie and Arizona have a difference in opinion on what their future holds, and Richard tries to adjust to his role as a surgeon.

The Grey Sloan Memorial doctors grapple with the aftermath of the car crash that involved some of their own; Meredith works to save Dr. Hamilton's life. Levi is impacted from his latest loss.

Jo returns for her first full day back from leave, and Owen struggles to keep it together when someone close to him is admitted to Grey Sloan. Meanwhile, Bailey navigates hospital leadership.

Meredith has a court hearing after skipping out on community service, while Bailey and Jo have a patient that Jo realizes is from the treatment facility. Richard and Gemma grab breakfast together and things go awry.

Tensions at Grey Sloan Memorial rise as the effects of the physician shortage begin to show. Meanwhile, Meredith struggles to step away from work as she spends a sick day at home with Zola, and the hospital receives an unexpected visitor.

DeLuca is irritated after Meredith takes over his patient Suzanne whose symptoms continue to stump the doctors at Grey Sloan. Elsewhere in the hospital, Jackson, Owen and Jo work on a couple injured in a bear attack; and Levi is hurt when Nico doesn’t want him to meet his parents.

The doctors of Grey Sloan Memorial must contend with the COVID-19 pandemic; an unintentionally started fire has first responders from Station 19 bringing patients into the hospital for treatment.

In the immediate aftermath of shocking events at the clinic, the hospital goes on lockdown and the Grey Sloan doctors split up to save multiple lives; Maggie lands in hot water with Winston; Jules' roommate makes a surprise appearance.

Dr. Arizona Robbins returns to Grey Sloan for a particularly complicated case. The interns are interrogated about their past mistakes, while Teddy is eager to return to work after her health scare.

Richard finds out Maggie quit Grey Sloan and is concerned about how she’s handling the death of her patient who was her estranged cousin. Bailey returns to work after taking some personal time off, although Koracick doesn’t make her first day as easy as she’d like. Meanwhile, Meredith thinks she might miss DeLuca, and Amelia has an update for Link on her pregnancy.

The team of doctors work on a high stakes case of a long time patient, adding additional pressure to an already tense environment. Meanwhile, Bailey wants Ben to kick out their new roommate, and Arizona is eager to get back into the dating world with a new wingman.

Amelia takes her personal problems out on her work colleagues, and the threats against Bailey come to a terrifying head. Lucas and Jules make a risky decision on a patient, and Mika struggles with burnout.

In the midst of a deadly heat wave, the team at Grey Sloan struggles to keep up with an overwhelming amount of patients. Amelia and Winston face a challenging surgery, while Jo and Lucas run an errand for the hospital that takes an unexpected turn.

Amelia undertakes a high-risk brain surgery on a young patient, while Winston and Jules disagree over how to handle their trauma patient's family. Jo and Link struggle with wedding planning.

While Meredith, Amelia and the team prepare for Dr. Hamilton’s long-awaited, groundbreaking surgery, Bailey receives an unexpected offer. Owen’s impatience makes him a difficult physical therapy patient, forcing Link to intervene. In Minnesota, Nick makes a liver transplant a teaching moment.

Teddy calls an emergency meeting to discuss the intern program. Link wrestles with his own self-doubt as he preps for a massive surgery, and Nick shares some much-needed guidance with a struggling Lucas.

Meredith takes a step forward with Will but quickly regrets it; Maggie senses a disconnection with Andrew; and Amelia reevaluates her relationship with Owen. Meanwhile, Catherine comes into town and really shakes things up with April and Jackson.

Meredith works on her relationship with Susan and Thatcher. Cristina has to deal with her mother and Burke's. Alex continues to tend to Jane Doe/Ava. Meredith and Derek's relationship has a problem that needs resolution quick. Addison sees her god-daughter which leads to a job offer outside of Seattle. Derek has to perform surgery. Burke has a reservation about marrying Cristina. Many new people guest star in the course of Addison's road trip to California. Addison considers moving to be closer to her old med school friends until she discovers that drama she wishes to leave behind isn't exclusive to Seattle. Her friends who she thought had it all, are divorced. A pregnant woman must discover who the father of her child is.

Ties are strained as Andrew and Carina confront an unforgiving family history. Meanwhile, Teddy and Owen work together on a married couple who is expecting, and Amelia attends a conference for alternative pain relief.

As Meredith puts Zola to bed and falls asleep, she begins to wonder -- what if her mother had never had Alzheimer's and she'd had loving, supportive parents? The reverberations of a happy Meredith Grey change the world of Seattle Grace as we know it. What if she had never met Derek in that bar and he had never separated from Addison? What if Callie and Owen had become a couple long before she met Arizona? And what if Bailey never evolved from the meek intern she once was?

Simone and Lucas work to balance their relationship while competing to assist on an awake kidney transplant. Teddy offers Amelia a new opportunity, and Ben's interview doesn't go as planned. Meredith's secret causes tension with Richard.

The team at Grey Sloan navigates a chaotic first day of surgical rotations amid hospital renovations. Meanwhile, Meredith spends time with Amelia.

An earthquake shakes the ground at Grey Sloan Memorial Hospital, trapping Maggie in an elevator and threatening Meredith’s long streak of successful surgeries. Meanwhile, Owen gives medical advice to a child over the phone and Ben confides in Jackson.

Tensions rise as Teddy and Winston take on a complex procedure, while Kavita and Ben try and impress the new plastics attending. Jo and Link leave the babies with a nanny for the first time.

Grey Sloan Memorial faces new pressures as Seattle Pres is overloaded, and Grey Sloan Memorial is now on surge capacity protocol. Meanwhile, Owen and Amelia are faced with one of the most controversial surgeries of their careers.

April is in charge of the new Grey Sloan Surgical Innovation Contest, and the doctors are eager to start their projects. Meanwhile, Catherine’s old friend has a shocking idea for Catherine and Jackson; and Meredith treats a returning patient who inspires her project.

A couple lands in the hospital with life-altering injuries after a wrecking ball destroys their home. Lucas and Simone struggle to support a young, terminally ill patient, and Richard hosts a prostate screening event.

Meredith questions Link’s laid-back approach over a patient’s treatment. Maggie worries that Richard, Jackson and Catherine haven’t come to terms with Catherine’s diagnosis. Meanwhile, Deluca steps up in the O.R. when Owen faces a setback.

Maggie and Jackson are enjoying spending time together, but he must turn his concentration toward the groundbreaking vaginoplasty surgery he has scheduled with Catherine and Richard. Meanwhile, Meredith and Jo hit a roadblock with their contest submission, so Jo helps Bailey with an incoming trauma patient who used to be an astronaut

Jackson learns about April's pregnancy, while Alex and the team of doctors handle an hours-long triple-organ transplant surgery. Meredith considers dating again, and Andrew insists on not receiving special treatment after he and Maggie go public.

As Adele's condition continues to deteriorate, Richard considers altering their living situation; an explosion at a local coffee shop results in a busy day in the ER for the doctors; Callie takes Meredith under her wing by helping her study for her boards; Lexie joins Arizona and Alex in peds, as they continue to care for intern Morgan's premature son; and when Jackson snaps at a patient, Mark encourages him to find ways to relieve his stress. Meanwhile, Cristina lets her suspicions get the best of her.

Meredith, rattled by the latest events, tries to figure out what to do about Derek. Meanwhile, Owen is shocked when his mother is admitted to the hospital.

It's all hands on deck at Grey Sloan when a group of medical students is injured by a floor collapsing at their white coat party. Jo and Link are forced to talk about the future, while Jules confronts Winston about his attitude.

Maggie gets upset when Meredith dodges her questions about DC; Bailey and Ben become concerned about Ben’s brother after he is admitted to the hospital, and Dr. Herman starts to warm up to Arizona. Meanwhile, Richard feels manipulated by Catherine.