The events of Carlo and his family come to an end.

Chicco and Maddalena's last night as singles. A revelation ruins everything.

Chicco resolves the crisis with Maddalena. Annamaria improves in therapy. Sandra and Sofia team up and Carlo and Ema go to Paris to convince Paul McCartney to be the "super guest" but Ema ruins everything. A meeting at the airport offers the solution.

Carlo acts in a commercial and a tragedy makes him reflect on his role as a teacher.

The Festival starts badly: food poisoning strikes Carlo and others. Maccio, Carlo's worst nightmare, has a secret relationship with Ema. Sandra and Sofia arrive in Sanremo. Carlo regrets having accepted, but he must go on stage.

Carlo is in Nice and has no intention of returning to Rome, but a proposal will change everything.

Carlo is on his first day of shooting and discovers that Sangiovanni has also abandoned the film. Between anxiety, panic attacks and the early birth of his daughter, the day turns into an experience of reflection and acceptance of life.

The Festival was a success, but on the eve of the last night, a gaffe makes him a target on social media. While everything seems over, Maddalena and Chicco take an important step. Carlo reflects on the storm that has hit him. How will he get out of it?

Chicco and Maddalena are in crisis. He lives with Carlo with the baby, while she is busy with work and is getting closer to Diego. Carlo hires Eva, a babysitter that everyone likes, maybe too much by Chicco. He discovers the talent of Lucio Corsi for Sanremo.

Having accepted the artistic direction of the Festival, Carlo calls Thomas, an expert organizer, who warns him of the difficulties. Worried, Carlo goes to his nephew's baptism, but Maddalena does not arrive in time, causing a family crisis.

Carlo invites Maccio and Ema to the family dinner. The evening degenerates: Carlo discovers that Eva is on OnlyFans; Eva reveals that Annamaria is a gambling addict; Maccio falls in love with Ema; Giovanni is dumped and Sofia reveals a secret about Carlo and Sandra.

Maddalena gets a job and Chicco becomes a stay-at-home dad. Sandra gets engaged and Sofia is arrested, Giovanni is with a conspiracy theorist and Annamaria faces a vice and a new neighbor. Carlo receives an unexpected offer. Will he accept?

Rome needs a mayor who knows this city inside and out. Someone who loves it as the Romans love it. ...And who better than Carlo Verdone? When Signoretti, the president of the Lazio Region, asks Verdone to run for mayor the actor promises to think about it, but due to a series of coincidences the news reaches Roberto D'Agostino's ears - which makes it dramatically public.

Carlo's first appointment with the pharmacist Annalisa is disturbed by a girl looking for the morning-after pill. Carlo will recover the pill thanks to the help of Virgilio (Rocco Papaleo), finally managing to end his evening.

Carlo, a guest on "Belve," is put in difficulty by Francesca Fagnani.

While Carlo manages to foil an attempted suicide at the Colosseum, strengthening his popularity as a candidate for mayor of Rome, at home his son Giovanni is busy organizing a party. Here, he meets Giorgia, a singer with whom he establishes an immediate harmony. Meanwhile, the marriage of the pharmacist Annalisa seems to have come to an end, and for Carlo there seems to be the first real chance to win her heart.

After the waste scandal, the mayor resigns and early elections are expected. Carlo can no longer waste time. Besieged by journalists, by the President of the Region, by the Producer, by the Screenwriter and with Annamaria, his twenty-year-old housekeeper, who resigns and Magdalene who does not answer his phone calls, Carlo exhausted, to find peace, takes refuge in a monastery where the unexpected encounter with a somewhat extravagant musician will take place: Morgan, depressed for having been the victim of ghosting.

New year's eve in the cabin turns into a nightmare: Annamaria disappears and Carlo investigates.

Carlo and Max want to go to the stadium to watch the Roma match but on the way the driver argues on the phone with his lover and crashes into some dumpsters. Carlo and Max are forced to follow the game from the hospital as they try to clear themselves with the police, who, pursued by the suspected victim, suspect they were the ones who caused the accident.

At the exhibition of his friend Antonello Venditti, Carlo argues with his son Giovanni who accuses him of not being able to say NO to anyone. In fact, Carlo not only can't decide on the candidacy for mayor, but he can't even get rid of Chicco, his daughter's boyfriend, and put a stop to Erminia, a terminally ill who persecutes him with messages and phone calls.

Carlo and Sandra meet Alenka again, a Bosnian girl they adopted at a distance.

Rosa, Carlo's press officer, tries to deny the rumors that he is running for mayor. When the party, however, publishes a tweet in which he announces his candidacy and the news becomes public. Doubtful about what to do, during one of his usual nocturnal walks Carlo meets Alessandro Haber who, in the grip of alcohol fumes, brings him back to the most important theme: art.

At the Centro Sperimentale di Cinematografia, who is plotting against Carlo?

Cantalupo suggests to Carlo to organize a "team building" in Fregene to strengthen the harmony between the actors. During the stay, Ludovica and Sangiovanni experience nightly tensions, Sangiovanni runs away and finds refuge with Maria de Filippi.