5-year-old Haleigh Cummings mysteriously disappears overnight from her home near Jacksonville, Florida, after her dad's girlfriend puts her to bed. Was Haleigh abducted or did something else happen?

Newlyweds Jessica and Matthew Boynton seems like the picture-perfect couple until the young mother is found unresponsive and covered in blood.

A family camping trip to Timber Creek Campground in the remote Idaho mountains turns into something out of a horror movie when 2-year-old DeOrr Kunz disappears; at first it looks like he may have been abducted, until other disturbing theories start to emerge.

Beautiful mom Michelle Parker appears on an episode of "The People's Court", fighting with her ex-fiancé over a luxury diamond engagement ring; but hours after that episode airs Michelle mysteriously vanishes.

College student Elisa Lam checks into a Los Angeles hotel -- but never checks out. The last known images of the young tourist are from the hotel's elevator security camera. Later, her naked body is found floating face-up in the hotel's rooftop water tank.

32-year-old Rebecca Zahau seemed to have it all until she's found dead in a multi-million dollar mansion hanging from a balcony under bizarre circumstances; police rule her death a suicide, but some aren't buying it.

20-year-old Lauren Spierer goes for a night out with friends in June 2011; the gorgeous college coed has never been seen since.