Real Life Nightmare Episode Rating Graph

After leaving a friend's hotel, 17-year-old Brittanee Drexel suddenly disappears during spring break in Myrtle Beach; the case comes alive when twisted and disturbing details start to emerge from a prison cell.

6-year-old Timmothy Pitzen vanishes after a three-day trip to waterparks and the zoo with his mom. In a terrifying twist, his mom is found dead in a motel room with a disturbing note by her side.

After 7-year-old Kyron Horman's stepmother drops him off at a school science fair and takes a picture, the little boy is never seen again; his disappearance is one of the largest mysteries and investigations in Oregon's history.

20-year-old Lauren Spierer goes for a night out with friends in June 2011; the gorgeous college coed has never been seen since.

Newlyweds Jessica and Matthew Boynton seems like the picture-perfect couple until the young mother is found unresponsive and covered in blood.

In 2011, baby Lisa Irwin goes missing from her crib in the middle of the night and is never found. Stolen cell phones and a disturbing charge on a parent's debit card adds to the mystery.

35-year-old Crystal Rogers, a mother of five, goes missing and her car is found on the side of the Bluegrass Parkway with a flat tire and her keys, purse, and cell phone all left inside. But Rogers’ disappearance isn’t the only mystery casting a shadow over Bardstown, Kentucky.

Three young brothers are reported missing the day after Thanksgiving in 2010. In a shocking twist, their daddy claims he gave them to an underground group -- but investigators say his story doesn't add up.