Janine’s origins have always been a mystery, and Duri fears she may get terminal cancer like her mother.

A set of adopted triplets want to discover their ethnicity, and gene therapy could stop Leo going blind.

Olympic athlete Sarah wants to find her father. Jean, 91, wants to know if her mum died during WW2, and twins Tanya and Kim want to discover their origins before time runs out

Georgina was conceived 34 years ago when her mum had a holiday romance with a Portuguese waiter. She’s now wondering if her father is still alive. Matthew grew up never knowing his father’s identity and wants to know if his ancestry is actually Caribbean. Michaela and Richie only realised they could pass down the genetic disorder 'bubble boy disease' when they had their son Arlo. Now they’re testing their second child’s DNA to discover if he has to undergo life-saving gene therapy.

Kerry wants to establish her father's true identity. Twins Madison and Sydney want to find their egg donor, and Anthony, 77, wants to discover who his American GI father is.

Forty-six-year-old Mel only found out as a teenager that she was conceived using a sperm donor. Now she wants to see if she can find her biological father’s identity by decoding her DNA - and discovers far more than she ever expected. Fi always knew she was adopted. What she didn't know until later in life was that her father murdered her birth mother. Fi wants to know if it is possible to inherit a 'murder gene'. Bahaa escaped the war in Syria but now wants to know if he carries a potentially deadly mutation in his DNA.

Stacey meets five sisters in Lancashire who only found each other as adults. They know they all share the same mum but want to find out if they also have the same father. Luke was a sperm donor as a university student in the late 1980s. He’s now come forward to find out if any potential children might be looking for him. After losing their mother to cancer, identical twins Diane and Louise want to test their DNA to discover if they both carry the cancer-causing BRCA genetic mutation.

Charlotte looks for her dad after losing her mother. Rogie tries to find a secret sibling. And Lviss investigates whether his ancestry really is Nigerian.

Bill wants to learn what happened to his father, while Charlie asks if she is safe from a deadly disease.

Adopted Laura is searching for any siblings, Anthony, Sally and Karen want to uncover the truth about their father's other child, and Julie is looking for answers about her ancestry.