During a stopover in a small Kansas town, the agents become involved in a murder investigation. After a man is found guilty and sentenced to hang, the agents uncover valuable information that points in an entirely different direction. Of course, this information puts our agents into quite a bit of danger, but, as we know, they can handle themselves relatively well in these sorts of situations.

A stage coach carrying the western states entire supply of smallpox vaccine is attacked and the drug stolen. Furman Crotty, a convicted criminal serving time in Leavenworth, is demanding his release from jail with a full pardon and a ransom for the safe return of the drug. While Jim West, injured in the attack on the stage, struggles with amnesia, Artemus tries to find both his friend and the drug before a full-scale epidemic hits.

Investigating the disappeance of a correspondent of James West's, the agents come upon a bizarre family scheme. West's associate had a rare disorder that caused rapid aging, similar to that of the Sedgewick family. In an attempt to cure the disorder, the family physician has been kidnapping people with the similar disorder and using them to test a serum he has prepared. It is up to West and Gordon to stop his tests and bring him to justice.

James and Artemus arrive in Mexico with a present for the Mexican president-a beautiful Arabin horse. Within minutes of their arrival,however,the horse os stolen by a group of outlaw babdits.Our heros must battle the hot mexican desert to get the horse back before the outlaw Mexican ary beats them to it.

A Supreme Court justice will not believe his life is in danger---until a puppet-show marionette fires a gun at him.

Agent West raids a local warehouse in an attempt to apprehend a suspected opium gang member. As he struggles with the suspect, a new secret agent named Bosley Cranston rushes in and attempts to help. Unfortunately, he only makes matters worse, accidentally toppling a piano crate on the suspect and killing him. Cranston, however, is not the meek incompetent he appears and later surprises his colleagues with his karate skills and his popularity with beautiful women.

While trying to solve a murder, West is charged by a bullet-immune "ghost rider".

Something is happening in the small town of New Athens. residents are leaving in droves,scared off by a band of seedy cut-throats gathering just outside the town limits. And then there's Michael Trayne,back in town after three years in jail. Can Jim and Arte figure out what's happening and save the town before everyone leaves permanently?

While on the trail of a scientist who has stolen a vial of deadly germs, the agents are pulled into a night of deadly parlor games. West and Gordon must recover the vial before it bursts and releases a veritable plague while managing to live though the games of their host.

Someone is trying to run settlers off their land,buying some of them out,scaring other away,and even murdering those who refuse to leave. The government sends Jim and Arte in to investigate the situation and to stop whoever is behind this.

West finds Willow Springs looted and its citizens completely immobile---victims of a mysterious paralysis.

West is furious: his superiors have refused him permission to investigate the murder of a close friend who was burned to death before his eyes.

The guys become involved with a voodoo ceremony and the walking dead as they try to track down a missing scientist.

An ancient Aztec map leading to the lost treasure of Montezuma is discovered in Mexico and points to a location in Texas. In order to ensure that a diplomatic incident does not ensue,West and Gordon team up with Colonial Sanchez of Mexico and a noted archeologist in a dangerous trip across the Texan desert in search of the treasure.

A visit to the plantation of a US Senator reveals a myterious family past that intersects with a doctor infamous for his experiments with apes. The agents are lucky enough to arrive just as the Senator's forgotten giant son and his friend, a giant ape, are rampaging through the plantation.

Dr.Crane,inventor of a new explosive,is missing along with his daughter. If his ""doomsday formula"" falls into the wrong hands,especially foreign ones,it could mean the end of the United States. West and Gordon must rescue the professor,his daughter and the formula before it's too late.

James West and Artemus Gordon help evacuate the town of Tonka Flats before it is destroyed by a cannon shell. Afterwards, they are notified that a man identified as "The Falcon" has threatened to obliterate Denver unless the U.S. government pays him $1,000,000. "The Falcon" is also in cahoots with syndicate leaders from Turkey, Spain, Prussia and England. During their investigation, Gordon is threatened by a whip-wielding Spaniard named Munez who suspects Gordon knows too much about the top secret weapon. West rescues Gordon from Munez, who is then killed by an explosive meant for the two agents. While searching Munez's body, West and Gordon find an invitation from "The Falcon". Gordon, disguised as Munez, prepares to attend the meeting while West attempts to penetrate the stronghold where the cannon is housed.

Agent James West attempts to rescue a man called Mr.Markham from a masked assailant who flees the scene of the crime. As Markham lays dying,he utters two words-""enzo"" and ""silver"". Meanwhile,Agent Artemus Gordon has joined a troupe of entertainers traveling to Denver under the leadership of casino operator Kohner. Gordon,who is posing as a Shakespearean actor,learns that a man called Enzo has a girl friend,Topaze. She is a dancer with the troupe,probably working under an assumed name,and is on her way to meet Enzo in Denver. Dierdre,a dancer,attempts to pass some information to West but a jealous Kohner interrupts them and engages the agent in a fight with him and El Bardhoom,a huge weight lifter. Later,Artemus hears a strange voice of Markham's masked Killer. When West goes to meet Dierdre at midnight,he discovers that she too been slain by unseen assailant.

The stress of Secret service work appears to be finally getting to Jim as his temper flares and he makes mistakes. As West is being recruited by some member of the underworld who seeks to capitalize on his misfortune,Artemus and Conel Richmond struggle to find out exactly who,for what,and why.

Maharajah Singh kidnaps West for very unprincely reasons: West is to tutor Singh's assassin sons in the ways of Western combat.

West tries to protect Prof. Nielsen, a demolitions expert. But he fails: Nielson is blown up by the evil Dr. Miguelito Loveless.

Gordon and West head to a lonely outpost to battle a terrorist gang.

Agent West is summoned by a note from agent Gordon to the local barbershop. While waiting for Gordon, West decides to have a shave and is promptly anesthetised by a hot towel from one of Dr. Loveless's assistants, working in disguise. When he wakes up, he finds himself in a carnival funhouse where he encounters dazed-looking Justice Alonzo Fairlie. Before he can get any information from the judge, he is attacked by a quartet of gunmen. He quickly dispatches his adversaries but Justice Fairlie disappears in the confusion, leaving behined a strange clue.

Agents West and Gordon have been investigating a series of explosions that have demolished several palatial homes. While they are guests of the wealthy Mr. Taney, they hear a high, whining sound. Suddenly the house begins to crumble and the agents escape in the nick of time to see a giant tuning fork radiating powerful sound waves. As they delve deeper into the case, they discover a letter to Mr. Taney from the Cyclops Insurance Company, urging him to take out a policy against further destruction of his property.

The evil, diminutive Dr. Loveless impoverishes an Indian tribe so that he can become their benefactor -- and their god.

Investigating a murder, West falls into the hands of the Eccentrics, a group of assassins controlled by the vicious Count Manzeppi.

A series of mysterious deaths of military personnel bring Jim face to face with the indestructible Col. "Iron Man" Torres. Crippled in an explosion that he blames on the other men of his company, Torres rebuilt himself as a 19th century "cyborg", and is seeking revenge on those he thinks wronged him...and President Grant was one of the men he served with.

The agents travel to Hayes City to identify the body of their archnemesis, Dr.Loveless. While there, they meet up with Miguelito's next of kin, Dr.Liebknicht, a Swiss neurologist. However, as they pursue the origin of a key found on the body, they find that Loveless is hardly dead and has plans to use his neurologist guise to give Jim a lobotomy!

West is captured by a doctor who uses Pavlovian training to condition the Secret Service agent into becoming an assassin.

West gets involved in a bizarre scheme: a green girl emerges from a fallen spaceship claiming she needs gold for fuel.

West must protect a visiting despot from the fatal charms of Ecstasy La Joie, who brandishes such baubles as an explosive garter and a deadly ring.

West visits an eerie island to get a diamond for the National Museum.

West and Gordon escort President Grant to San Fransisco to dedicate a statue of the late Colonel Wayne Gibson in Gibsonville. West rides ahead to check out the town and finds that it is plagued by a series of broken-neck murders and arguments over lost gold. A further investigation yields the fact that the Colonel is not as dead as was previously thought and that his statue is far from ordinary.

Fabian Lavender is a master of disguises, but West is not fooled. Neither is Lavender --- who locks West in one of his gas-filled crypts.

Agents West and Gordon are sent to investigate the killings of wealthy industrialists and find that all are linked back to an evil matchmaker, Emma Valentine. She sets the rich men up with her young female employees and then kills them to gain their money and power. West and Gordon manage to escape from the trap she lays and must prevent her next target from getting married.

The plans of The Raven seem to be successful as they have hypnotized Jim West and had him assassinate the Mexican Ambassador. Unfortunately for the group,Frank Harper had been impersonating the ambassador to test whether Jim had been conditioned. West and Harper work together to infiltrate and undermine the group and capture everyone except for the huge-headed Tycho.

The U.S. State department is about to return a valuable samurai sword to its rightful owner,a Japanese prince,when it is stolen by an group of sword-wieding assailants. Jim and Artemus must located the sword and return it to the prince before he leaves the next afternoon,or risk damaging U.S.-Japan relations.

An escaped murderer plots a bizarre scheme against agent James West, the man who had imprisoned him several years earlier. Attacked and knocked unconscious, West awakens in a stange deserted town filled with assailants wearing masks in the likeness of Stark. Gordon searches for his lost partner and soon finds himself in a similar predicament. West and Gordon must avoid deception to find and take out the real Stark.

James West is tried by a court of cutthroats who believe he has murdered his friend and fellow agent, Artemus Gordon.

When Victor Freemantle, a dangerous revolutionary, steals the U.S. Constitution, agents James West and Artemus Gordon are sent by the government to the Panhandle Strip in Texas to recover it. West and Mr.Grigsby, a curator of the United States Archives, go to a secret underground hideout where Constitution is being held to verify the authenticity of the document. After determining that it is the genuine article, West and Grigsby are presented with Freemantle's demands: They are requested to cease negotiations with Mexico and the U.S. is to recognize the Panhandle Strip as a Sovereign enclave between the borders. A one-millon dollar ransom in gold must also be paid. As part of their agreement, Freemantle holds Grisby hostage until West returns. But West and agent Artemus Gordon decide to ignore the demands and rescue the Constitution themselves by infiltrating Freemantle's castle; Gordon disguises himself as a whiskey salesman and West hides underneath his wagon.

President Grant gives orders to agents James West and Artemus Gordon to deliver prisoner Rimsky to Vladivostok, Russia, in a prisoner exchange for American vice-consul Millard Boyer. When Rimsky dies in an escape attempt, Gordon assumes his identity. The agents are drugged en route and when they come to, are led to believe they're in Russia. West is imprisoned and forced to reveal Rimsky's whereabouts. His captors tie him to a stake while saber-swinging Cossacks ride straight for him. Still in disguise, Gordon meets Rimsky's contact Sazanov, in an effort to uncover the Russians' racket.

West meets up with Gordon, who has just arrived in New Orleans with a famous Italian diva and niece of the ambassador on his arm, an escort urged by President Grant. West agrees to substitute as the lady's guardian for her appearance that evening at the opera, but the performance is interrupted when Montebello's would-be kidnappers bring down the curtain and West jumps into the fray. Discovering that sereral divas had recently disappeared in New Orleans, the agents must rush to unravel a plot involving the secret Order of Lucia and reveal who among their new acquaintances is playing a role on and off the stage.

To rescue a kidnapped princess, Jim runs into a booby-trapped doorknob and a fully armored man wielding a mace.

West and Gordon are assigned to protect Dr. Raven, who is developing a secret weapon. Raven is a member of a tontine, an investment group whose bylaws state that the surviving member of the group gets the assets of the group. When one of the tontine's members is killed and an attempt is made on Raven's life, the agents decide to investigate. They find a house full of traps and two members of the tontine looking to "survive" the group and take the money for themselves.

West and Gordon are escorting the Sultan of Ramapur and his gift to the President, a sacred white elephant. Bandits intercept the train and steal the elephant, and the Sultan demands one million dollars in recompense. West follows the trail to a gypsy camp, where the elephant appears to have been colored grey as a disguise. Artie sneaks in as a peddler, and they try to recover the elephant. They soon discover that the elephant is not disguised, but instead is actually grey: it has been painted white and proclaimed sacred by the Sultan, who planned to extort the U.S. government all along. Confronted with the evidence, the Sultan is deported and the gypsies get to keep the elephant.

Agents West and Gordon are guarding a museum containing the famous Herzberg jewels but someone still manages to steal the gems. Afterward, a famous painting of a Western scene is removed from the museum by its wealthy rancher-owner. Gordon becomes suspicious and notifies West who discovers that the rancher is partners with Miguelito Loveless, the evil inventor-doctor. His latest invention is a machine that moves real people in and out of paintings. Miguelito's plan is to transpose murderers into famous paintings, distribute the paintings to the rulers of the world, and have them all killed!

After a series of disturbing incidents involving a raven that seems to hynoptize high-ranking officials into committing dastardly deeds,Agents West and Harper decide to find out what's going on. The incidents lead the new partners to a group calling themselves The Raven,led by Thaddeus Toombs and a man called Tycho (who has an enormous head and is very smart).

An Indian demand for gold must be met: they've threatened to kill five railroad workers a day until it is paid.

While on vacation, the agents receive an odd welcome when they pass through the town of Justice, Nevada. The town turns out to be the hangout for a group of international criminals assembled by Lucrese Posey. West and Gordon discover that Lucrese is planning on heading a worldwide criminal organization. After dealing with the other criminals, the two agents find themselves left with only Lucrese to deal with, a proposition not nearly as simple as it seems.

A mysterious figure in a secret cave makes moves on a chessboard, using a figure of James West. The agents start getting newspapers predicting the deaths of friends that haven't occurred yet. They are unable to stop the deaths but find the shop where the newspapers are printed. Following the trail, Jim is lured into the lair of Mr. Braine, a crippled criminal mastermind who gets about in a steam-powered munitions-armed wheelchair. Braine has planned their every move and response and wants Jim to join him in his plan to kill world leaders and replace them with lookalikes. He already has a double of Artemus Gordon. Braine has anticipated the real Artie sneaking in and taking the place of the lookalike, but Gordon double-bluffs him with a mask underneath his mask. taking advantage of the distraction, Jim confronts Braine and manages to defeat him, blowing up the wheelchair and Braine.

Agent James West goes to see Warden Primwick,who releases condemned murderer Ralph Kleed in his presence. Kleed blows a whistle,and the warden attacks West with his cane. West restrains the warden,who dies from the exertion. Kleed escapes,leaving behind a whistle that has a special pitch,apparently only heard by dogs and wardens. Through the warden's autopsy,agent Artemus Gordon discovers that a franconium crytal has been implanted in the warden's brain,prompting violent behavior when Kleed blew his whistle. West falls into the hands of master criminal Titus Trask,who intends to implant a crystal in the agent's brain and,in turn,have West do the same to President Grant so Trask can rule the country.

During Mardi Gras West is grabbed by Major Hazard: the leader of a gang of crippled Civil war soldiers seeking revenge on the camp's commandant, Mosely. Jim reluctantly agrees to help them, only to have Mosely taken from him by the soldiers. He tracks them to the abandoned camp, where it turns out that Hazard and his men aren't crippled. They were in league with Mosely, who stole a shipment of gold and hid it. Mosely double-crossed Hazard and his men, so now they want the gold. Thanks to a diversion by Artie (as a geologist who can find gold with a divining rod), Jim escapes and in the ensuing fight, Hazard is killed when the gold falls from its hiding place: the camp's water tower.

An attempt to assassinate President Grant is foiled at the last minute by West and Gordon. However,there seems to be more going on than a simple assassination,as the weapon used in the attempt was one stolen in recent raids on government and territorial armories. The President refuses to cancel a trip to Dever,leaving Jim and Artemus only 36 hours to uncover who is responsible and stop them before it's too late.

In the town of Epitaph, owned by Epitaph Mines, agents James West and Artemus Gordon arrest Norbert Plank, chief bookkeeper for the powerful syndicate that owns the mining company. Through Plank, the agents hope to get their hands on records that could build a case against the organization. The whole town turns out to free Plank, whom West has hidden in a church bell tower, while Gordon masquerades as lay-preacher Hallelujah Harry. Gordon hopes to get to the head of the syndicate, Diamond Dave Desmond, and walk off with the ledgers. But Diamond Dave's girlfriend, Rhoda, has the same idea and blackmail on her mind.

West and Pike receive a note to meet a woman at a Chinese restaurant in San Francisco with a promise of information about the militant Din Chang who has recently stolen a supply of fulminate of mercury from a military arsenal. Unfortunately, the woman is killed before they can talk to her and the only word she utters is "Pelican". To further complicate matters, the only person they manage to capture is supposedly still serving time at Alcatraz. Since it seems that Alcatraz and the woman are the two pieces they have of the puzzle, the two split up to track down Chang before he can use the volatile mercury.

West and Gordon are called into Mexico to investigate a group of bandits who are attacking and terrorizing border towns. They track the bandits to a Mexican Village where the theives are hiding under the guise of an old Mexican legend about Cortez. Jim and Arte,not believing in the return of the god Cortez,are determined to find their way into the dorment volcano where the thugs are hiding.

Time is running out for Judge M'Guigan, who is threatened by a bomb-throwing clockmaker.

Agents West and Gordon report to Admiral Agnow's San Francisco headquarters, only to find him and three officers dead. The agents believe that the admiral's death ties in with the recent mysterious sinking of the cruiser Youngstown. West and Gordon's next assignment is to guard the Hawaiian king, due to arrive secretly by ship. West encounters Barclay, a Chinese expert on Hawaii, to discuss the king's upcoming visit. But the supposed advisor drugs the agent and announces his plan to sink the ship carrying the Hawaiian king.

West and Gordon are called to the deserted mining town of Brimstone by a Professor Colecrest who has made a discovery of great importance. However, before they get to Brimstone, the Professor is captured by a gang of men also seeking his discovery. The professor, seriously injured in a fall, holds the key to the mystery, and Jim and Artie struggle to keep him alive until they can uncover the true root of the mystery.

Jim and Artemus try to recover stolen radioactive materials nad have only one clue - a set of fingerprints found on the ankle of a pretty secretary.

Intent on making California a kingdom for children, evil Dr. Loveless makes his play for the state with a series of toys---which explode.

On the trail of the source of mysterious tidal waves, the guys finds a fanatical marine environmentalist at the heart of the mystery.