Hime is transferred into Megumi's school under the Japanese name Hime Shirayuki, becoming excited at the thought of making 'one hundred friends'. Upon arriving at school however, she is overcome with fear and finds herself unable to face anyone properly. Megumi tries to get Hime to make friends with Yuko, but she becomes too afraid and turns away from her. Whilst lamenting her actions alone in the gym storage, Hime meets a teacher having his own worries about his students not listening to him. Just then, Namakeruda appears and uses the teacher to create a Cone Saiark. Hime initially struggles against the Saiark, but becomes strengthened by her desire to protect the school and make some friends, defeating the Saiark with help from her new form, Sherbert Ballet. Afterwards, Hime gives the teacher some words of encouragement before working up the courage to become friends with Yuko.

On their way to Megumi's house, Megumi and Hime end up doing a lot of good deeds, such as clearing up litter, treating a injured puppy, helping a lost child, and giving someone courage to propose to his girlfriend. After having pancakes with Megumi and her mother, Hime laments how her parents were trapped inside mirrors by the Phantom Empire, whilst Megumi tells her how she wants to help out her mother, who has a weak body, citing her as the reason she loves helping others. Hosshiiwa takes advantage of Megumi's helping nature to lure her and Hime into a trap, attacking them with a Mole Saiark. As Hosshiiwa passes off Megumi's desire to help others as self-satisfaction, Hime stands by her side, believing in the genuine good feelings from helping others, and manages to break them free from the Saiark and defeat it. Afterwards, Megumi gives Hime her thanks for standing by her beliefs.

Ribbon gets upset at Hime when she doesn't want to eat her home cooking and has lunch at Yuko's house instead. Wanting Hime to understand the feelings behind cooking, Yuko asks her to help out at her family's bento shop, where she learns how much hard work goes into preparing food for others. Just as Megumi brings Ribbon over so Hime can apologize, Namakeruda appears with a Bento Saiark to target the shop. Determined to protect the shop, Hime understands the effort Ribbon puts into her cooking and fights back with her Macademia HulaDance form, allowing Megumi to defeat the Saiark. Afterwards, Hime apologizes to Ribbon for her behavior and the two manage to make up with each other.

As Hime decides to hold a 'special party' at her house, Megumi shows up early with the intention of helping out with preparations. Hime, however, wants to prepare the cake she was making by herself, kicking Megumi and Ribbon out of the house when they try to help her out. As Megumi wonders what exactly she did wrong, Ribbon explains that Hime wanted to prepare the cake herself as a surprise for her. Meanwhile, Hosshiiwa targets a newlywed couple and creates a Wedding Cake Saiark, which Hime attempts to fight on her own, but ends up getting overwhelmed. Megumi arrives in time to protect her, with Megumi apologizing for not understanding her feelings and Hime apologising for getting mad at her.

With the HappinessCharge Pretty Cure gaining popularity thanks to TV coverage, Megumi and Hime attend the local festival with some of Megumi's friends, where Hime ends up spending all of her allowance quickly, but enjoys making new friends. The girls decide to have their fortunes read by Iona Hikawa, a girl from the class next to Megumi's, who foretells a terrible future for Megumi and Hime. Just then, Oresky, another commander from the Phantom Empire, targets Megumi's friends and creates two Matsuri Saiarks, which take the Cures off guard. As the Cures are driven into a corner, Cure Fortune appears and single handedly defeats the Saiarks, before telling Megumi that she is better off not partnering with Hime, believing she can't be trusted.

Lamenting over their last battle, Megumi and Hime decide they need to train their bodies. Seiji takes them to his local karate dojo where Iona also practises, along with Megumi's friend Kazumi. The girls are impatient to learn about the advanced fighting techniques, but Seiji insists they start with basic techniques. The next day, as Kazumi nervously prepares to take an exam to improve her rank, she is targeted by Oresky, who creates a Karate Saiark to attack the dojo. As the Cures rush into attack, Megumi is injured from defending Hime from a feint attack. Just as things look their worse, a mysterious new Pretty Cure named Cure Honey uses a soothing song to put the Saiark under her control and give the Cures the encouragement to defeat the Saiark using the techniques they learnt from Seiji. After Cure Honey takes her leave, Kazumi is encouraged to try her hardest in her exam.

Having been caught on a television broadcast, Cure Honey's song has caught on with almost all of the students, much to the dismay of the choir club president, Hitomi, who wants her club to practise seriously for an upcoming contest. Hitomi becomes upset when the rest of the choir club speak up against her strictness, wanting to perform something for more fun, and becomes targeted by Hosshiiwa, who creates a Music Saiark and uses her own song to spread her chaos, desiring to face Cure Honey. Sure enough, Cure Honey shows up to face Hosshiiwa in a vocal showdown and comes out as the winner. Cure Honey then shows off the power of her Honey Baton to help Megumi and Hime defeat the Saiark. Afterwards, as Hitomi makes up with the choir club, choosing to go with Cure Honey's song for the contest, Yuko reveals to Megumi and Hime that she herself is Cure Honey.

Blue explains that he gave Yuko the power to become a Pretty Cure prior to Megumi, though Yuko decides to withhold telling her secret right away. The next day, Yuko invites Megumi, Hime, and Seiji to the mountains, where they all help Yuko's grandparents plant rice used in her family's restaurant. Although Hime is eager to know why Yuko kept quiet about her identity, she comes to understand more of Yuko's kindness. Just then, Namakeruda appears and targets Yuko's grandparents to create a Scarecrow Saiark, with Megumi and Hime unable to fight easily in the mud. As Yuko joins the fight, she discovers the Saiark is resilient to her song, but she is soon supported by Megumi and Hime and manages to defeat the Saiark with her Popcorn Cheer form and her Honey Baton. Afterwards, as the girls eat the rewards of their work, Yuko explains the feelings behind delicious are the reason she became a Pretty Cure, revealing she was too embarrassed to come forward before.

Megumi ends up ranking in the bottom two in her class and has to take a retest or else face after-school lessons for the rest of the school year, along with her classmate Kenta, who is more interested in baseball than studies. Megumi is put under further pressure when Blue threatens to suspend her from Pretty Cure activities should she fail her next test. Whilst Hime and Yuko help Megumi with her studies, Seiji teaches Kenta the importance of studying. On his way home to study, Kenta is targeted by Namakeruda, who creates a Baseball Saiark which Megumi challenges to a baseball match. After a series of foul balls, Megumi manages to figure out the pattern of the Saiark's pitches and land a home run, allowing her to defeat the Saiark. Afterwards, Megumi and Kenta study hard and manage to pass their retests.

On Mother's Day, Megumi and Yuko suggest to Hime that they travel to the Blue Sky Kingdom so she can deliver specially made cakes to her mother, who became trapped in a mirror when the Phantom Empire invaded. Blue allows the girls to go, but warns them to avoid battles as much as possible, as their Pretty Cure powers will be weakened due to the Phantom Empire's influence. Arriving in the Blue Sky Kingdom, the girls use their Ninja outfits to avoid detection by the Choiarks as they make their way towards the palace, where they have to get past several Knight Saiarks. After using a hidden passageway, the group arrive at the throne room where Hime's imprisoned parents are. After delivering Hime's cakes to her mother, the girls transform to escape, but are soon discovered by Hosshiiwa, Namakeruda, and Oresky, who send a trio of Saiarks after them.

Wanting to support Seiji as he participates in a karate tournament, the girls decide to make him lunchboxes, which Hime isn't particularly skilled at. Whilst out shopping for ingredients, Hime encounters Seiji practising his karate, becoming curious as to why he works so hard at it. Just then, Oresky targets another karate student and created a Karate Saiark, with Seiji offering to help hold off the Choiarks for Hime. As Megumi and Yuko come to their aid, Seiji explains that it was Megumi who inspired him and Yuko to keep doing their best, giving Hime the encouragement to work hard too and defeat the Saiark alongside Megumi. Afterwards, Hime gives her all to make some omelettes for Seiji, who manages to win his tournament.

Yuko and her family are asked to cater for a wedding between two customers, Sachiyo and Daisuke, with Megumi and her friends offering to help out with preparations and Hime suggesting they use the theme of 'four somethings' for the bride's outfit. However, Sachiyo informs the group that her best friend who was supposed to give her 'something borrowed', Iona's older sister Maria, has gone missing, so the girls ask Iona to deliver it in her place. On the day of the wedding, after Iona gives Sachiyo Maria's handkerchief, Hosshiiwa crashes the wedding and creates a Bride Saiark from the newlywed couple. Determined to protect the wedding, Cure Fortune appears and leads the Cures to victory, allowing the celebrations to continue.

Whilst on the train back home, Hime and Seiji stop by a station to get a drink. However, when the vending machine ends up giving them too many prize drinks in a row, the train departs with Hime's Pretty Change Mirror and Seiji's Cure Line phone still on it. As the two leave the station in search of a payphone, Hime is troubled by a sprained ankle, so Seiji treats it and offers to carry her. The pair are soon confronted by Hosshiiwa and her Delinquent Saiark and Choiarks, with Seiji stepping up to defend Hime from the Choiarks before Megumi and the others arrive to help. Angered by Hosshiiwa's poor treatment of Seiji, Hime, who regains her Pretty Change Mirror, gains the strength to defeat the Saiark by herself. As the group make their way back home, Hime fears that she herself has developed a crush on Seiji.

As the group work to finish their summer homework, Hime finds it hard to be around Seiji, eventually confiding in Yuko and Iona. After an awkward lunch together, Yuko mentions to Hime that Megumi appears to have a crush on Blue, also mentioning she one had a failed love herself. Meanwhile, Seiji calls Blue out to ask him what he thinks about Megumi, not feeling satisfied by his answer. Just as Hime catches up to Seiji, Namakeruda targets him and creates a Chef Saiark. Despite their worries, both Megumi and Hime realise that, regardless of feelings, Seiji is still precious to them and unite their powers to defeat the Saiark. Afterwards, Hime comes to realise her feelings for Seiji weren't actually love, deciding to support Megumi and Seiji instead.

As Yuko starts helping out Pretty Cures from around the world, the girls are approached by Aloalo, the fairy partner of Hawaii's Pretty Cure team, Alo~ha Pretty Cure, who have been struggling against the Phantom Empire's commanders, Madam Momere. The girls travel to Hawaii, which has been completely frozen over, to meet up with twin sisters Ohana and Olina, a.k.a. Cure Sunset and Cure Wave respectively, who are struggling to get along with each other due to their different methods of fighting. After Yuko uses her lunches to help lighten the mood between them, the sisters decide to put aside their squabbles and work together with the HappinessCharge Cures for the sake of saving Hawaii. After the HappinessCharge defeat one of Madam Momere's Saiarks, Ohana and Olina realise the importance of their sisterly bond and work together to defeat the other Saiark, returning Hawaii back to normal.

Blue explains that the Cures can use the Axia's true power, the Shining Make Dresser, to once again seal Queen Mirage. However, Megumi objects, believing Blue doesn't truly want to fight Mirage, whilst Iona argues against her, stating that defeating Mirage is the only way to save the captured Pretty Cures. The next day, after both Megumi and Iona sort out their feelings with help from Yuko and Seiji, the girls ask Blue about what happened between him and Mirage. Blue met Mirage 300 years ago, when she was a just a simple shrine maiden working at Pikari Shrine, and despite having feelings for her, he chose not to stay by her side for the sake of loving everyone on Earth, which led to her becoming Queen Mirage. As the girls encourage Blue to tell Mirage his true feelings, Blue decides that they need to awaken Axia in order to face the Phantom Empire in the Blue Sky Kingdom.

As the girls try to figure out the secrets of the Shining Make Dresser, Blue reveals that Mirage was once a Pretty Cure herself who battled alongside him. Shortly afterwards, Megumi and Blue are confronted by Phantom, who uses Megumi's shadow to turn himself into a dark double of Cure Lovely named Unlovely. Armed with knowledge of Megumi's desire to help her mother, Unlovely uses psychological attacks on Megumi, leaving her vulnerable to her attacks. With Unlovely's power proving to outmatch the other Cures, Megumi is left doubting herself, but Hime and the others help to encourage her to stand up again, giving her the strength to fight against Unlovely, turning her back into Phantom. The Cures' innocent thoughts grant them the power to use the Shining Make Dresser and perform the Happiness Big Bang attack to beat Phantom.

Phantom, who was knocked unconscious in the previous battle, is taken in by the girls to have his injuries treated. Yuko decides to take over looking after Phantom, leading to some misinterpretations from the other girls. When asked by Phantom as to why she bothers to help him, Yuko rekindles memories of a dog who got into an accident, which inspired her to develop her cooking skills and nurse him back to health. Despite the dog passing away two years ago, Yuko remained determined to use her food to help those in need, be they friend or foe. Just as Phantom reveals the only way to undo the sealing curse on Maria and the other defeated Pretty Cures is to defeat him, the Cures are alerted to an attack by Oresky and his Tree Saiark. While Megumi, Hime, and Iona fight against Oresky, Yuko encourages Phantom to put aside his hatred for Blue and return safely to Mirage's side, before joining the others in defeating the Saiark.

Wanting to earn her own Innocent Form, Megumi decides to step up her efforts in helping others. She comes across Mami Jindaiji, a budding scientist trying to build her own rocket, and decides to help her with her research. However, Megumi ends up doing a lot of unnecessary things, including washing Mami's lab coat which she promised not to clean until she had finished her rocket, and ends up feeling she is only being a nuisance. After speaking with Seiji, Megumi instead decides to make some cookies to give Mami some encouragement. The next day, however, Oresky targets Mami and creates a Rocket Saiark, wanting to launch her rocket for himself. Determined to both protect Mami's rocket and help her reach her dream, Megumi keeps on fighting before the others arrive to help defeat the Saiark. Afterwards, Mami successfully launches her rocket, becoming more encouraged in reaching her dream, with Megumi also learning something from the experience.

Hime is excited for the school culture festival, which would be her first, and tries to help out as much as possible, but struggles to find something she can help out with. Luckily, the student council president gets Hime to help him put up posters around the school, learning the festival is all about everyone working together. She later gets by everyone to help make the front gate look appealing. The next day, as the festival gets underway, Namakeruda appears and targets the student council president to create a Festival Saiark. As Hime strives to protect the gate that everyone made together, she awakens her Innocent Form, using its power to help defeat the Saiark.

On the day before Megumi's birthday, the other girls work on party preparations while Megumi spends time with her father, who has come home from work. During this time, Megumi becomes downhearted when she hears her mother is already on the mend, effectively making her wish to make her better meaningless. As her funk carries over to the next day during her party, feeling her resolve to help others has been shaken, she receives encouragement from both Seiji and Blue. Just then, Oresky crashes the party and targets all the guests to create a Present Saiark. Offering to share her party celebrations with Oresky, Megumi understands that the feeling of making everyone happy is greater than being thanked for it and unlocks her Innocent Form. After defeating the Saiark, Megumi decides to work towards a wish to make everyone happy, while Mirage prepares to make her move.

With Pikarigaoka celebrating Halloween, the girls invite Blue to join them for a costume parade, much to Seiji's dismay. As everyone becomes obsessed with sharing pumpkin cakes, Hime becomes concerned about Seiji, who is jealous of Blue growing closer with Megumi. Just then, Oresky attacks with a Pumpkin Saiark, desperate to prove himself as number one after learning Mirage is planning to bring out a stronger enemy. With Megumi hearing about Oresky's fears of being considered worthless if he can't be the top, the Cures defeat the Saiark and attempt to purify Oresky, but their Big Bang attack is stopped by Mirage's new enforcer who, to Iona's shock, is revealed to be none other than her kidnapped sister, Maria.

With Mirage free from evil's grip and the Blue Sky Kingdom returned to normal, the girls decide to have a pajama party to celebrate their victory. The next morning, Seiji, noticing Megumi looking down, takes her out on the town to clear her mind. When asked whether or not saving everyone has made her truly happy, Megumi confesses that she is heartbroken over Blue choosing Mirage over her and lets out her feelings. Just then, a powerful Red Saiark appears before Megumi as the mysterious youth attempts to use his influence to put her under his control, but Seiji's voice helps Megumi regain her senses and remove the red crystal that was manipulating her. Accepting the pain of lost love to pursue true happiness, Megumi fights back against the Red Saiark and manages to defeat it with the other Cures. The mysterious youth is encountered by Blue, revealed to be named Red as he decides to go after Seiji.

Megumi informs Blue about the man she encountered before joining Hime and the others for a Christmas lunch. After helping Yuko's store sell some special lunches, the girls exchange scarves with each other, with Megumi also giving Seiji a scarf of his own. Later, as the girls pick out presents for Blue and the others, Seiji gets Megumi a brooch for her present. Just then, another Red Saiark attacks, distracting the Cures from the mysterious youth as he targets Seiji with a red crystal. Though the Cures manage to defeat the Saiark, they are confronted by the mysterious youth, Red, revealed to be a god like Blue who has turned Seiji into an evil knight under his control.

Seiji, controlled by Red's crystal, attacks the Cures, who attempt to break the crystal only to find themselves pushed back and overwhelmed by his power. After explaining that his crystal only allowed Seiji to embrace the hatred he now bares towards Megumi for her failure to realize his feelings for her, Red uses his power to send a large red planet crashing towards Earth while legions of Red Saiarks spread across the world before he and Seiji take their leave. Just as Megumi feels helpless, blaming herself for not understanding Seiji's feelings, Maria arrives just in time to protect her from a Saiark, reminding the Cures not to give up so easily and instead use their desire to save those they care about to gain new strength. With the other Cures from around the world giving them encouragement, the HappinessCharge Cures stand up once more to beat the Saiark before setting off to the red planet to confront Red and rescue Seiji.

As Blue, Mirage, and PhanPhan watch from the Pikari Shrine, the Pretty Cures attempt to make their way to the red planet when Seiji appears and attacks them. The others attempt to remind Seiji of who he is to create an opportunity for Megumi to reach him, the two crash landing on the red planet, Red points that the only way for it to be removed from Seiji is either his death or Megumi's. Megumi tells Red that she has come to understand Seiji's feelings, strengthening her resolve to convey her feelings to him in a one-on-one battle. Breaking through Seiji's attacks, Megumi confesses her gratitude and love for Seiji while reaching his true feelings. This allows the Cures to destroy Red's crystal and purify Seiji back to his normal self. Shocked by this turn of events, Red is furthered angered by Blue and Megumi saying that love can overcome hatred as he resolves to personally destroy everything.

The Cures begin their fight against Red, pitting their love against his hatred. Despite the Cures using Innocent Purification against him, Red manages to successfully withstand their attack and fights back, knocking the Cures out of their Innocent Forms and trapping them inside mirrors, with Seiji becoming trapped himself in order to protect Megumi. Red reveals he was the god of the Red Planet which was destroyed long ago, his failure to protect it causing him to lose faith in love and instead turn to hatred, wanting to destroy Earth so that Blue could feel the same pain. Understanding his pain, Megumi offers to help Red fulfil his true wish and receives power from the collective prayers of Cures around the world, transforming her into Forever Lovely.