A 64-year-old is rushed to hospital after falling onto fire stoking tools; a 48-year-old man is brought in after having been beaten with a baseball bat and bitten.

Thirty-nine-year-old Ricky arrives at hospital in an ambulance after falling through a glass window. Dr Zak Duthie is tasked with treating the patient, but Ricky makes it very clear he does not want any needles near him.

In Birmingham, staff handle a severe asthma attack and a brutal assault. In Tunbridge Wells, a patient collapses in triage, leaving the team fighting to save his life.

A young man has to be restrained by police officers and security personnel in the ambulance bay after shouting and swearing at medical staff. Simon is rushed to hospital with serious injuries after being thrown off his horse and cart at high speed, and an initial CT scan reveals the 73-year-old has multiple broken bones.

Hull Royal Infirmary staff have to deal with abusive patients disrupting care due to Covid restrictions preventing family members from entering the waiting room. After her motorcycle collided with a deer at 60mph, 56-year-old Tracy is rushed in, and consultant Dr Andy must establish why she is having trouble feeling her legs, while Adam is devastated when an accident in the gym means he may not be able to compete in Hull's strongest man contest.

Lifting the lid on the night shift as experienced by A&E workers, with exclusive access to Hull Royal Infirmary. The night-time challenges facing NHS staff are captured in their raw form.

A 19-year-old woman comes to Hull Royal Infirmary after falling off a barstool in a pub and landing on her little finger, while a 53-year-old man arrives after blacking out and falling down a flight of stairs in his block of flats. Meanwhile, staff deal with a 34-year-old who has been thrown off his motocross bike in a race and has fractured and dislocated both shoulders.

The return of the documentary going behind the scenes at Hull Royal Infirmary to show the night-time challenges facing NHS staff working in the A&E department. A patient in police custody is brought in for treatment to a split eyebrow and some facial wounds, while the resus team attempts to save the life of a patient who is rushed into hospital in cardiac arrest.

In Rotherham's A&E a patient with a suspected head injury is under arrest in the car park. In London, an eye injury from mixing concrete requires action to prevent permanent damage.

Nurse Simone has a drunk patient and his equally drunk friend who have passed out in a cubicle, Nurse Sheena must examine a 50-year-old man's puncture wounds from a dog attack. Dr Kaylee is working quickly to investigate a suspected broken ankle, and Dr Luke is concerned with a patients breathing difficulties, who has been brought into resus in a diabetic coma.

A man is rushed in to Majors suffering with a collapsed lung and air is leaking into his chest cavity, a highly abusive patient must be restrained, and a rough sleeper comes in with burnt feet.

A+E Departments are seeing alcohol abuse on the rise and in Rotherham an alcohol-dependent patient arrives at the rapid assessment unit after faceplanting onto concrete. The patient is agitated but Dr Alex's primary concern is spinal damage and brain injury. They transfer the patient to resus just in time to intercept a seizure. Time is critical but this patient's behaviour is getting in the way of a life-saving brain scan.

A 34-year-old man is brought in after having punched his arm through a pub window. Handcuffed and accompanied by four police officers, his behaviour has medical staff fearing for the wellbeing of other patients. Matron Kat Henry deals with a flirtatious patient who has cut his head after a night out on the town and is determined to leave the hospital without treatment.

In North London security must manage an abusive man as he refuses to leave, despite being discharged and a patient suffering from a heroin overdose is rushed to Rotherham General Hospital’s resus. Coming to his wit’s end with a severe toothache, patient Kieran’s abscess spreads to his airways and Doctor Mehran must decide whether he needs emergency surgery. Plus, security guard Justin suffers a head wound after being attacked when he tried to prevent a theft at his work.

Police bring in an abusive male under arrest who claims he has a racing heart, and two friends arrive in resus who have dislocated each other's shoulders during a friendly wrestle.

A&E in London's North Middlesex University Hospital is heating up thanks to an aggressive male who claims he has been attacked. Language is a barrier but by a stroke of luck, Advanced Clinical Practitioner Albena translates. The patient is incoherent, threatening, and is a risk to others, so security stand close until his suspected psychosis can be managed.