In the story of a Los Angeles kidnapping, ransom and murder ring, retired scientists use sonar equipment to locate victims at the bottom of a reservoir.

A young Texas teenager and her boyfriend are brutally attacked on Valentine’s Day; she is found dead while her boyfriend escapes. The case goes cold for nearly 50 years before a new forensic test exposes a family man with a dark secret.

When a 23-year-old Marine dies in his bedroom, doctors initially believe a heart attack is to blame. When arsenic is found in his organs, his wife is charged with murder; a sharp attorney and toxicological testing uncover the truth.

When an 18-year-old girl is abducted while talking on a payphone, forensic evidence found on her clothing points police in the direction of a suspect who shockingly confesses that he didn't act alone.

Investigators search for clues after a body is discovered in a Florida waterway.

An early morning house fire kills the only doctor in the small town of Iaeger, WV. An arson investigation quickly leads to the arrest of Jason Lively, the son of the doctor’s long-time nurse. But when Jason’s alleged accomplice walks free, the prosecutor is worried this might have been a miscarriage of justice.

A single mom looking for love vanishes without a trace. Foul play is tragically confirmed when a large pickup truck toolbox opens to her body stuffed inside. Homicide detectives investigate men she matched on dating sites, another man she met at work, and finally, a lover with a secret and violent past.

In 1982, 37-year-old Navy lieutenant Lee Hartley is murdered while deployed out to sea. Cause of death? Arsenic poisoning. Investigators discover Lee had more than his fair share of enemies aboard the ship. But it takes years before investigators discover what really happened to Lee and who, ultimately, was behind this brutal murder.

A building manager finds the violated and lifeless body of a young woman in the bathtub of her first apartment. When questioned, an ex-con living downstairs lies to police. But the lies alone do not prove murder and the case goes cold. Then, a new forensic tool examines the old evidence.

The body of a 24-year-old criminology student is found wrapped in a blanket alongside a desolate Road in Brooklyn, New York. Police zero in on the bouncer at a SoHo bar.

The murder of a young teacher’s aide leaves a hole in the heart of her small community in Agawam, MA. As the rumor-mill about suspects churned, the actual perpetrator slips further away. But, generations of investigators and a scientific breakthrough leads to a shocking end to a tragic case.

A Texas ex-con resolves to live a clean life after his release from prison. When he’s later arrested and convicted for a bloody murder, he insists he’s innocent. From behind bars, he’s determined to use forensic science to prove his case.

He is a criminally charged sex offender and a murderer who attacks in a terrifying rage. This predator manages to evade capture for years, but he leaves a critical piece of evidence behind – his palm print. Detectives are determined to do whatever it takes to put a name and a face to the print.

A healthy, young mother mysteriously dies after a minor traffic accident triggering an investigation to find out what caused her death.

After a young mom is found brutally murdered in her home, investigators find startling clues on her cellphone that could lead to her killer.

After the brutal slaying of a young couple on a road trip, the victims' families begin receiving disturbing letters.

Police race to find a serial killer terrorizing a small Texas town.

A 33-year-old West Virginia husband and father seemingly dies in an accidental house fire; a closer look at the scene reveals a more sinister case.

After a 79-year-old woman is found shot to death in her home, shell casings and a high-tech database reveal the unlikely killer.

A family mourns the unexpected death of a beloved grandmother at Christmas, and while local police assure everyone that she was the victim of a tragic accident, some things about the scene don't add up.

After the discovery of the brutal murder of an 18-year-old desk clerk of a beachfront condo, analysts use brand-new mitochondrial DNA technology to prove the killer's identity.

A true-crime enthusiast may connect a Jane Doe to a missing persons case in Ohio.

A Texas love triangle turns deadly, and it appears to be an open-and-shut case until technology tells the tale.

Eight days after she had disappeared on her way to a family ski trip, an 18-year-old young woman's partially nude body is found floating in a river in Wyoming. Years later, DNA technology uncovers dark secrets that led to her demise.

When the 20-year-old clerk of an Atlanta-area smoke shop is gunned down during a robbery, investigators use a videotaped confession to smoke out the killers.

A massive explosion claims the life of a California farmhand. Authorities think it’s an accidental death, but analysis of debris shows it’s a bomb. Investigators have few suspects until they hear ominous rumors about a jealous rage.

A hearing-impaired 77-year-old on a road trip is attacked by a thief and shot to death. Why? Because the man cannot hear his assailant’s demands. Random murders are among the hardest crimes to solve, but investigators are determined to bring this killer or killers to justice. Can advances in ballistics testing crack the case?

An upscale apparel store in Bethesda, MD, is the site of a gruesome scene when an employee is killed and her co-worker is battered and tied up, but surveillance video and blood evidence shed further light on the crime.

A young Colorado mother suddenly vanishes on Thanksgiving, but when police trace her cell phone, it leads them to a surprising character with an even more surprising story.

A young mother is found murdered in her home and there are two suspects with ample motive, but an unusual interview and security camera footage have investigators puzzled.

A popular handyman in a New Hampshire town is found murdered and investigators follow forensic clues to a shocking conclusion.

On a brutally cold winter night in 1984, a young woman is found viciously murdered on the side of a rural Wisconsin driveway. The victim, Traci Hammerberg, had been out with friends for a night of drinking and partying. What happened? Detectives initially have plenty of suspects, but the investigation would remain unsolved. Until nearly three decades later, when forensics from an unrelated crime helps breaks the case.

Someone targets members of law enforcement in a peaceful Texas county. Numerous suspects emerge, and murders continue as detectives race against time. Finally, a single bullet casing uncovers the bizarre reason for which the killer wanted revenge.

Investigators think they know who killed a young woman, but the case goes cold. An amazing new forensic tool turns the cold case around.