Peyton Manning heads west to Malibu, CA, to meet up with Chargers head coach Jim Harbaugh to help him spend a day in his favorite TV show, The Rockford Files, climaxing in a wild ride along the California coast that would make Jim Rockford proud.

After successfully freeing the Detroit Lions from "The Curse of Bobby Layne", Peyton Manning gets ambushed by former Buffalo Bills wide receiver Steve Tasker and The Bills Mafia, who demand Peyton lift "The Buffalo Sports Curse". After hearing their pleas, Peyton meets up with Bills quarterback Josh Allen as they attempt to lift the curse.

Peyton meets up with former linebacker Brian Bosworth to learn how "The Boz" built a brand around his alter ego.

After finding the original Madden Cruiser at the Hall of Fame, Peyton "borrows" the bus and travels cross country to the places that made John Madden one of the most beloved figures in football.

Peyton prepares his best sales pitches to entice venture capitalist Mark Cuban to invest in football inventions that are ready for the market.

Peyton enlists help from former teammate Pat McAfee to explore the history of punters and the demise of the coffin-corner kick.

John Elway, one of the NFL’s most revered quarterbacks and Manning’s former boss, breaks down film at Mile High Stadium in Denver and chat with each other.

Peyton looks at the origins of fantasy football.

Hall of Fame quarterbacks Roger Staubach (Cowboys) and Joe Montana (49ers/Chiefs) help Peyton explore the evolution of the quarterback and how it became the most important position in all of sport – and the face of every NFL franchise.

Peyton looks at the history of football in Chicago and visits with two Bears super fans.

Host of CNBC’s Mad Money Jim Cramer welcomes Peyton to Wall Street where they discover how the stock market crash of 1929 led to the creation of the NFL Draft. Also, Peyton explores how an IBM 360 computer and Mel Kiper, a draftnik with no credentials, helped turn the draft into must-see television.

This time, fans will join Manning as he enlists the help of Ron Jaworski to learn how Thomas Edison produced the first game film when he recorded Princeton versus Yale in 1903. He then meets up with James Van Der Beek to break down the play of the greatest movie quarterbacks of all-time.

The former NFL quarterback will chat with Kurt Russell as they talk about his character, Reno Hightower, from the movie The Best of Times. It also stars the late Robin Williams as a banker looking to restage a game where he dropped a perfectly thrown pass that cost his team the game.

Owens is one of the biggest and most widely misunderstood personalities in NFL history. Peyton meets with T.O. to talk about his Hall of Fame career and larger-than-life persona.

Manning meets up with the former late-night host at Ball State, Letterman’s alma mater. The future Hall of Famer enlists the help of the football team to propose new rules for the sport.

The mobile quarterback of the modern NFL owes some of its DNA to Tarkenton, who broke free from the mold of pocket QB.

The former NFL quarterback heads to West Point. There he meets up with former United States President, Bill Clinton, and they journey to learn about the history of the forward pass.

Peyton and Eagles legend Ricky Watters dress up as Santa Claus and throw snowballs at Eagles fans to exact revenge for the notorious “Santa Game”.

Peyton Manning heads to Philadelphia, where he switches places Freaky Friday style with former Eagles center Jason Kelce to learn about the history of the quarterback sneak. Peyton becomes the center of attention as he experiences the Tush Push from Kelce's perspective.

When Peyton can't quite explain the NFL's Passer Efficiency Rating to a math class at his alma mater, the former Tennessee Volunteer enlists the help of Falcons quarterback Kirk Cousins to get to the bottom of the NFL's most confusing statistic.

When Patriots owner Robert Kraft asks former Patriots Rob Gronkowski and Julian Edelman to pay for damages to New England's Super Bowl LI Trophy, Peyton takes them to Rhode Island where the trio try to build a Lombardi Trophy from scratch.

Peyton drives a 1920s Hupmobile with comedian Jay Leno and learns how the NFL started with a car and a car salesman, Ralph Hay, in Canton, Ohio. He visits with Joe Namath, playing pool and discussing how Namath led the New York Jets to the historic Super Bowl III victory.