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Katherine Connor and her children run an elephant sanctuary that rescues, rehabilitates, and re-wilds elephants from Thailand's tourism and logging industries. Now she wants to rescue an older elephant, Pang Fai, and release her from chains forever.

Animal Defenders International (ADI), led by Jan Creamer and Tim Phillips, has already helped ban the animal circus industry in over 40 countries. When their organization arrives in Peru, they embark on their biggest animal rescue challenge yet.

Ali Bee, her husband Tim, and daughter Izzy spend their time rescuing and rehabilitating koalas in their home in Australia. Crikey the koala was a baby that was found alone and very sick. Now, it's time for the family to release him into the wild.

Derrick Campana specializes in designing prosthetics and orthotic braces for animals. Derrick will fit Jabu, an elephant in Botswana with a life-threatening injury, with the world's first elephant orthotic leg brace, hoping to save his life.

Seven-year-old social media sensation Roman McConn and his mom, Jen, have saved over 1,500 shelter dogs by connecting them with adopters around the country. The duo have 1 month to find homes for over 100 shelter dogs, including Noah, Rocky and Migo.

With the help of her two daughters and husband Phil, Donna Stepan runs Sleepy Burrow Wombat Sanctuary. She takes in a new orphaned baby in critical condition and the next 24 hours become a fight for its life.

Theresa and Tony “Scruff” Matthews turned their dream retirement home in Australia into a full-time kangaroo rescue. They’re ready to release kangaroos Lisa, Luna, and Barbie, but an injury might threaten one of them returning to the wild.

Cute Cumber, an orphaned baby dwarf pony with leg deformities, was saved by Ashely and her 3-year-old son, Deacon and brought to their home rescue, Twist of Fate Farm. Now, they are determined to find this fragile animal the perfect family.