Surgeons at Addenbrooke’s operate against the clock to remove a kidney from a husband and transplant it into his wife who is in end stage kidney failure.

Surgeons at Addenbrooke’s Major Trauma Centre must operate on a single mum who has a severed spinal cord and a critically injured motorcyclist.

Addenbrooke’s surgeons take on two high-risk operations; surgery to excise tumours near the spinal cord and a procedure to remove a dangerous mass off the body’s largest vein.

Surgeons Marius Berman and Pedro Catarino take on one of the most difficult transplant procedures at Royal Papworth: the double lung transplant. With donor organs in such short supply, there is even more pressure to execute the operation perfectly.

Addenbrooke’s major trauma team and surgeons treat some of the country's most critically injured patients. Multiple teams must decide whether a man's damaged arm can be saved.

Surgeons at Addenbrooke’s Hospital take on life changing surgery that takes two specialist surgeons two days to perform and involves removing all the organs in the patient’s pelvis.

Surgeons at Royal Papworth and Addenbrooke's hospitals must put their patients back together again after removing life-threatening lung and facial tumours.

David Jenkins, a world-leading surgeon at Royal Papworth, performs one of surgery's most technically demanding, and extraordinary, operations. Called a pulmonary endarterectomy (PTE), no other hospital in the UK offers this procedure.

Surgeons at University Hospital Southampton operating on two patients - removing rare tumours and correcting a patient’s bowed legs - must alter their plans to avoid catastrophe.

Surgeons at Addenbrooke’s Hospital perform brain surgery on a patient who is awake and attempt to repair a section of the body’s biggest blood vessel that’s threatening to burst.

Surgeons at Addenbrooke’s Major Trauma Centre must operate on two road accident victims who have suffered life-changing injuries so serious they could lead to an amputation.

Surgeons at Addenbrooke’s Hospital perform a complex procedure to help a patient swallow again and remove a tumour that is threatening a patient’s vision.

Surgeons attempt to save a patient’s life and her ability to smile, by removing a tumour in her cheek and reconstructing her facial nerve.

Surgeons attempt a rare and high-risk transplant to transform their 21-year-old patient’s life, and perform a complex kidney procedure vital for another patient’s survival.

Surgeons battle to save a patient with an aggressive tumour and a patient whose aorta – the body’s biggest artery – could rupture at any moment.

Three surgeons operate together on a motorcyclist at University Hospital Southampton’s major trauma centre after a crash leaves the patient with life-changing injuries.

Surgeons at NHS Lothian take on high risk surgery to repair a failing heart and take extreme measures to prevent the return of breast cancer in their young patient.

Surgeons at University Hospital Southampton face complex surgery to reconstruct a patient’s jaw and remove a cancerous oesophagus.

The series returns to the operating theatres of the Queen Elizabeth Hospital Birmingham. A neurosurgeon has to wake his patient up during an operation to remove his brain tumour.

The extraordinary stories of clinical trials being carried out at the surgical unit at the Queen Elizabeth Hospital Birmingham.

Surgeons have to balance the considerable risks of a procedure against the risks of not treating their patients' conditions at all. Maureen has an enlarged aorta which could be fatal if it bursts, but the operation to fix it is also very high risk.

Addenbrooke’s surgeons perform life changing scoliosis surgery to straighten the spine of their 17-year-old patient but face the risk of causing paralysis.