After traveling through a magic portal to puberty headquarters, Nick seeks out a new Hormone Monster and Jessi bonds with the Depression Kitty.

As the kids creep closer to adulthood, a memorable finale takes them back to where it all began to say goodbye — and face the future.

Andrew tries to drown his sorrows in a sea of porn, only to become hopelessly addicted. Coach Steve becomes a suspect in a murder spree.

Nick tries to lighten the mood at the sleepover with a new twist on Truth or Dare. The Shame Wizard meets his match. Jessi vows to change her ways.

When a freak storm gives everyone new superpowers, tensions between Andrew, Nick and friends boil over into an epic showdown.

A school sleepover turns messy as Nick dishes on a makeout session and the Shame Wizard works his miserable magic on the whole class.

When Leah hosts a party for the high school drama crowd, Nick wrestles with a romantic dilemma, and Andrew and Missy witness a disturbing scene.

Coach Steve finally gets his chance to do sex on a lady, Nick and Andrew go on a double date, and Jessi's rebellious streak leads to big trouble.

As Nick tries to figure out whether he has a shot with Gina, a mortifying encounter with Leah sends Andrew into a spiral of shame.

Family blowups, secret liaisons and an unflattering dress make Jessi's bat mitzvah a night to remember.

A classmate's booming bosom sends the boys into a rapture -- and leaves the girls with a raging case of insecurity. Coach Steve drops a bombshell.

A steamy novel making the rounds at school inspires Jessi to explore her own sexuality -- and leaves the boys totally confused about what girls want.

Connie gives Jessi a crash course in female pleasure, Maury tries to talk Andrew into sending a dick pic, and Nick lashes out at his new housemate.

A provocative school musical unleashes Missy's inner thespian -- and her new Hormone Monstress. The "Queer Eye" Fab Five pay a visit to Coach Steve.

While Nick tags along with the Gloubermans on a wild road trip to Florida, Jay discovers he's been "Home Alone'd" -- and moves in with a new family.

Jessi and Nick dip into her dad's stash of edibles, with mind-bending results. Andrew searches for the right moment to break up with Lola.

When a shop class mishap inspires a sexist dress code, Jessi rebels, Missy struggles to keep her alter ego in check, and Andrew gets a wake-up call.

Connie recruits a Compassion Pachyderm to teach the kids how to see things from another point of view. Andrew sets out to steal Missy's man.

As the friends feverishly swap lists of the hottest kids at school, newcomer Ali stokes the flames by announcing she's pansexual.

A sudden outbreak of body-swapping yields awkward situations and poignant revelations galore.

A big standardized test sends everyone into a panic -- except for Jay, who just scored an Adderall prescription.

During a sleepover, Jay teaches Andrew how to defend himself against bullies. Then, Missy gets overwhelmed while back-to-school shopping with Jessi.

Eager to get his mojo back, the Shame Wizard drops in on swim class to torment the kids with bodily insecurities.

A field trip goes from awkward to mortifying as Jessi navigates the demands of coupledom and gets her first period -- inside the Statue of Liberty.

Lola hits the jackpot — in more ways than one. Missy takes her dad to Elijah's church. The Birches make a plan to get rid of their new housemate.

Elijah tries to figure out why he doesn't have the same urges as his friends. A jealous Andrew hops a train to Vermont to surprise Bernie

Big Mouth goes global for a very special episode as Maury and Connie take a closer look at how kids around the world experience puberty.

The voice of a slick, new tech accessory hypnotizes people into doing things they wouldn't normally do. Missy grapples with the concept of sin.

Classic holiday stories get a naughty makeover in this special episode hosted by puppet versions of Maury and Connie.

A DNA test leads Nick to uncover a wee family secret. Jay insists on introducing Matthew to the Bilzerian clan. Andrew puts his lovebug to the test.

A doctor puts Andrew on testicular rest, Nick asks Jay to help him get in shape for high school and Jessi becomes fascinated by Caitlin's breastfeeding.

While Andrew and Nick deal with parental crises, Jessi meets her new sibling, and Matthew realizes he's made Jay into a different person.

At their first high school party, Andrew discovers his talent for drinking games, Nick hopes for a shot with Danni, and Missy meets a potential rebound.

While Andrew prepares for a momentous evening with Bernie, Nick sets out to meet his secret grandfather, and Jay cooks up some romance for Matthew.

While Jessi sorts through her feelings for Ali, Nick joins Devon for a boys' night, Andrew shows off his new persona, and Missy starts a rumor online.

As Walter the love bug coaches Nick on matters of the heart, Jesse gets fired up about protesting the school's problematic mascot.

Andrew takes a liking to his new neighbor — and her mom. Nick wants to be more than Danni's friend, but her entanglement with Travis gets in the way.

Matthew explores his sexual preferences, Nick says the wrong thing, and Missy uses Andrew to make Nate jealous. Jessi finds a surprise on Camden's phone.

The ghost of Duke Ellington takes Nick and friends on a journey back in time to 1913: the year he lost his virginity and found his true calling.

A reckless Lola gets behind the wheel, and Jessi and her mom have a really big fight. Nick's mother finds his "special shirt" while cleaning his room.

Unrequited love and jealous rivalries turn the friends into seething beasts. Andrew gets a little too invested in a substitute teacher.

On the last night of camp, bowel problems, a talent show and a hookup lead to hurt feelings. Back home, Jay and Lola throw a pool party.

A viral quiz about naughty deeds sparks arguments and unlikely new friendships. Matthew plans a baby shower for Maury.

Missy tries to show her cousins she's not a dork, Andrew takes a stand against his dad's turkey tyranny, and Jesse hopes for a Thanksgiving miracle.

After being snowed in with their families, the restless friends flock to Bridgeton's latest make-out spot. A new classmate catches Missy's eye.

With a big dance approaching, FOMO's everywhere: Missy misses school, Matthew dives into the deep end — and Andrew suspects that Other Andrew is evil.

Nick drags Andrew into the city to visit an old camp crush, but the day doesn't go as planned. Jay embarks on an emotional journey with his pillow.

Jessi and Jay pair up to parent a melon "baby," Missy faces her fears, and Nick and Other Andrew try to fit in with a group of ultra-rich kids.