Giacomo's provisional release re-starts the investigation into the crime at the golf club. Meanwhile, Alice discovers that someone is looking for information on Manes: perhaps the person she so desires to meet is closer to her than she imagines. For Alice and Claudio the day set for the wedding has arrived, but it passes in vain.

Claudio and Alice follow an intuition that can exonerate Giacomo. Paolone is also summoned for his first report: the mysterious death by poisoning of a well-known food critic. Alice's stubbornness, meanwhile, leads her to make one last attempt in the quest that the Supreme had given up.

Alice is destroyed by suspicions of Claudio's betrayal and returns the engagement ring, sending him into a rage. To cheer her up, Wally involves her in her secret project and Silvia suggests reprisals. Meanwhile, a famous trapper is killed just before a concert and the difficult expertise is entrusted to the Suprema herself, who decides to take Alice with her. Sandro sees an opportunity and decides to come forward with Alice, but does not realize that Claudio has seen it all ...

During the investigation into the attempted murder of a theater director, Alice senses the reason for the rust between Conforti and Einardi: between the two there is a war that risks involving her. During the investigations, which also bring up Cordelia, Alice's roommate, a formidable scientific intuition of the student reveals the motive for the attempted murder.

Claudio and Alice continue to have opposite points of view on love. Meanwhile Ambra mysteriously disappears and Claudio seems to be very worried. A pharmacy robbery degenerated into murder leads Alice and Conforti to meet Einardi again, who once again does not hide a keen interest in the student. In the meantime, the Supreme Prof. Malcomess, director of the Institute, communicates the decision to retire, opening the race to his succession and calling for a competition among the trainees for a scholarship in Baltimore.

Claudio does his utmost to protect Alice, but at the same time keeps her at a distance, while trying to prove Giacomo's innocence. Meanwhile, Lara asks Alice to collaborate on her first appraisal: a boy died while doing parkour and it is necessary to carry out the relevant findings. Just when Erika realizes that her feelings for Paolone go far beyond friendship, he moves away.

The death of an elderly playboy during the funeral of a friend of grandmother Amalia's and the unexpected involvement of her grandmother in the investigation push Alice and Lara to entrust Camilla to the most unlikely babysitter: Cordelia. Meanwhile, someone has enrolled Paolone in a cooking talent, but the outcome will not be quite what they hoped for. Alice has a formidable intuition that could prove Giacomo's innocence and to verify it goes beyond the limits of what is allowed.

Alice and Claudio begin preparations for the wedding, but she notices that he is hiding something from her. While Alice is working on the murder case of an old prof. in psychiatry, the historic friendship with Lara and Paolone is put to the test by the doctoral announcement: there are only two places up for grabs, the loser will have to leave the institute.

Alice can't talk to Arthur: above all she doesn't know how to tell him that she and Claudio will leave alone for his first medical congress. Meanwhile, the mysterious disappearance of a woman calls Alice into Claudio's case.

Alice is a young graduate in medicine who does not yet know what specialization to take, nor what to really do in her life. The death of her grandmother's caregiver, which occurred under unclear circumstances, will make her choose forensic medicine.

Alice did it: now she is a specialist in Forensic Medicine! He understood that life inside the Institute will be anything but easy, but soon something new knocks on his door. His name is Arthur.

A new case involves our coroners: a boy in custody dies of respiratory failure following a fatal stroke. Meanwhile, love and work do not run in the same direction.

Could it be true that in love who flees wins? Arthur is gone and Alice, who hasn't heard from him for days, is in a panic. Meanwhile, a diver dies during a competition: according to Claudio it is an obvious case of doping.

Alice, on the eve of the first dinner at the Malcomess home, feels more insecure than ever. Meanwhile, the owner of a beauty clinic dies before undergoing plastic surgery.

An African woman is found dead on a provincial road. Scarred with acid, she is supposed to be a prostitute. However, the detail of a tribal scar allows Alice to trace her identity.

Things with Arthur are not going well: Alice feels him distant and they often quarrel. Meanwhile, the case of a woman found dead while jogging distracts her from her study.