With Jackson missing, Mitch and Abraham race to find him before General Davies and the International Animal Defense Group can locate him and prevent the team from making a cure. Also, Jamie, Dariela and Allison make a last-ditch effort to convince the Russian government to drop out of the Noah Objective.

Mitch and Jamie brave an animal attack at the Russian Embassy in Washington, D.C., and Jackson finally gets the answers he’s been looking for from a surprising source.

Chloe tries to bring light to the rising threat from the animals. Jackson is taken to a hospital and while they are there Mitch works to create a cure. However, there are many obstacles they must overcome.

Jackson faces the most difficult decision of his life. Also, Mitch reluctantly enlists help from his father, Max Morgan, to investigate the origin of the final set of triple helix animal bones,

After the team’s plane suffers a catastrophic accident in the hybrid zone, Dariela and Tessa set out on a rescue mission to save them.

Jaime and Logan arrive at Caraquet, but things are not what they seem. The group tries to save Chloe.

The team travels to Portugal where they square off against a dangerous venom dealer in order to get one step closer to the cure. Also, Jackson's increasingly erratic behavior jeopardizes the entire team.

Mitch digs into Jackson’s past to get the answers they need to make the cure. Also, the rest of the team hunts for evidence related to the triple helix inside a quaint English town.

Jackson learns his mother is missing in Africa, but before he can look for her, he and the team must contend with a hostile force that has overtaken their plane. Also, Jamie learns a shocking secret about Abraham.

Jackson discovers that Abraham is alive and stages a daring rescue to bring his friend home safely. Meanwhile, Jamie suspects that Reiden Global's pesticide is responsible for the lion attacks and convinces Mitch to help her. In Paris, a mysterious man approaches Chloe and asks her to accompany him.

The team races to stop the hybrids from breaching the barrier wall by shutting down the last beacon that draws them in.

Abraham works to save Chloe and Mitch from a drug lord; Jackson and Jamie continue to work with Agent Shaffer in search of Evan Lee Hartley and the Mother Cell after Leo is killed in the crash.

Ten years after the animals were cured but at the cost of sterilizing the human population, a new threat rises in the form of “the hybrids,” an army of unstoppable lab-made creatures focused on destroying mankind.

Jackson, Jamie and Agent Shaffer search for a chemist in Alabama who has evidence of Reiden Global's role in the growing animal problem. Meanwhile, Chloe, Mitch and Abraham fly to Rio de Janeiro to delay the local government's plan for a massive bat extermination and come up against a ruthless drug lord.

After Mitch’s alter ego, Mr. Duncan, attacks the team’s plane then flees, Jamie, Abe and Max set out to find him and help.

Abigail holds Jackson prisoner in order to extract information from him that is critical to her secret master plan, and the team faces a mid-air crisis when their plane experiences an electrical malfunction

Abraham and Dariela reunite with the team as they try and stop the hybrids from taking over New York City.

The team discovers a terrifying rat infestation when a cargo ship carrying the bloodthirsty rodents washes up off the coast of Massachusetts. Also, unbeknownst to the rest of the team, Mitch reconnects with his terminally ill daughter in Boston as he prepares to make a trade with Reiden-Global to save her life.