Shocking confessions are made as the Red Devil is finally unmasked and the killer revealed.

The Green Meanie sets its final plan for revenge in motion as Hester makes a bold move to secure her future, and Brock performs a dangerous surgery to save Dean Munsch's life.

Chad takes Chanel to his family home for Thanksgiving, where she meets his brothers, Brad and Thad, as well as his parents. However, an uninvited guest throws the holiday into chaos. Meanwhile, Dean Munsch gathers the survivors at Kappa House, but dinner quickly explodes into accusations of who among them is really the killer. Then, the Red Devil carves up a deadly main course as another victim falls.

The Chanels are overwhelmed when their TV idol, Dr. Scarlett Lovin, visits the C.U.R.E. Institute. Meanwhile, Hester calls a Green Meanie summit as the killer(s) put their final kill plan into effect.

Shocking confessions are made as the Red Devil is finally unmasked and the killer revealed.

A new patient with a hideous ailment visits the hospital in hope of a cure, but finds a love interest instead. Meanwhile, Chad returns to win Chanel back and, in the process, discovers a dark secret of Brock’s. Then, after another run-in with the killer, Munsch enlists the help of new Quantico special agent Denise Hemphill.

The frightful events of Halloween force Dean Munsch to notify authorities of murders at the Institute, which leads to a surprising influx of new patients. Meanwhile,Chanel is tired of doing dirty work, so she concocts a plan that entails recruiting new patients to join the Chanels. Later, Zayday and Chanel #5 visit a person with ties to the hospital's past; and a new patient's problems have the staff going a bit mad.

Twenty years after a mysterious death rocks Wallace University, another murder takes place.

Dean Munsch is left in a desperate situation when a shocking event leads her to come face-to-face with her ex-husband's mistress. Meanwhile, in an attempt to determine who the Red Devil killer is, the Kappas use a Ouija board to communicate with Chanel #2 from beyond the grave and learn of a wicked plot against one of their own.

Grace enlists Chanel’s help to learn more about KKT’s past, and ends up realizing she might not be so different from her nemesis after all. Dean Munsch goes “psycho” when she becomes the latest target of the Red Devils. Meanwhile, Denise becomes the new house mother of Kappa House and a shocking figure from the past returns.

In an attempt to protect herself from the killer, Chanel makes a surprising decision, which leaves Zayday in a position of power. To stay close to each other, the girls of Kappa Kappa Tau host a slumber party, but when a shocking discovery is made, not everyone will survive the night.

Chanel finds a new project in Hester, Chanel #3 confesses a secret and Grace and Zayday uncover a surprising connection between two fellow students. Meanwhile, Denise sets her sights on one of the Kappas, and Dean Munsch appoints a new Wallace University mascot as Chad and Earl Grey lead the fraternity on a witch hunt for the Red Devil.

When anti-Kappa Dean Cathy Munsch decrees that sorority pledging must be open to all students, and not just the school’s silver-spooned elite, all hell is about to break loose, as a devil-clad killer begins wreaking havoc across the campus.

Years after the murderous events at Kappa House, Dean Munsch purchases an abandoned hospital under the guise of fixing the healthcare system in America. After recruiting surgeons, Dr. Brock Holt and Dr. Cassidy Cascade, as well as medical student Zayday Williams, the Dean shocks everyone when she enlists the services of the disgraced Chanels to join the ranks at the teaching hospital. Meanwhile, secrets from the hospital’s past begin to reveal themselves and a new killer surfaces.