In Ohio, Truck Hunters Shawn and Vince must track down and deliver a big rig filled with highly classified cargo but mid-route they pick up a mysterious tail. In Texas, a trailer filled with prized cattle is stranded on a track, and Marshall and Korchenko is the trucker's last hope to avert a disastrous collision. In New Jersey, brothers-in-law John and Gene are on the hunt for a hijacked truck full of a million dollars worth of laptops. And in Denver, Animal and Steve discover the perils of trying to deliver a hot load on a tight deadline, as the President's visit locks down the city's traffic grid.

The Jersey Boys, John and Gene, go to blows with a delinquent driver who isn't paying the bills on his truck lease. Ex Cons, Shawn and Vince, are sent to rescue a disabled tractor and its load, but this big rig is for the birds, literally. The Texans, Marshall and Korchenko, put their perfect recovery record to the test as a disoriented driver can't give them his whereabouts. And The Desert Dogs, Eric and Rob, a father and son truck hunting duo, must deal with a disgruntled driver who won't hand over his rig.

The Vets chase after a rogue driver who is out to stick it to the trucking company. The Jersey Boys are called in to rescue a driver who has been attacked by hijackers. The Texans are on a long hunt for 16 tons of frozen shrimp. And the Ex-Cons must track down a big rig that's been taken off the grid by a driver who thinks his truck is being followed by space aliens.

The Texans must hunt down and take back a stolen rig, before the thieves cross into Mexico. In Arizona, The Desert Dogs are called in to sniff out a snake. In Ohio, The Ex Cons kick into high gear hunting for a missing race. And The Jersey Boys are called in to take possession of a backhoe that a disgruntled trucker is holding hostage.

The Jersey boys, John and Gene, are called out of Newark and out of their element in search of a stolen tractor. The Ex-cons, Shawn and Vince, run into a series of unfortunate events after securing a truck with a high value load that needs to get to Houston. And the Vets, Animal and Steve turn up a load of produce that's not fit for human consumption.

The Ex-Cons chase down a missing load with a $5,000.00 bounty, but they're not the only bounty-hunters on the job. The Texans, Korchenko and Marshall, search scrapyards in the pre-dawn hours after a load of drilling pipe vanishes. And Jersey Boys, John and Gene, search high and low (and through strip clubs) in Newark's underbelly.

The Desert Dogs have a hot lead on a hot-headed trailer thief whose finally come back to town, while the Jersey Boys John and Gene are called to try and solve a cold case which takes them to danger-filled Atlantic City. Meanwhile, Animal and Steve are on a wild goose chase with a driver who is holding a load hostage and the Ex-cons chase down a stolen truck filled with beer.

The Jersey boys need to find an abandoned rig and take it to the port before its ship sails, while the Vets are close to blows after a hard night leaves Steve 50 shades of cranky. And the ex-cons risk life and limb driving up the highest road in the country to pull a tractor back from the ledge.