In 1989, Jeni Gray inexplicably vanished while on a morning walk in Boone. Police were perplexed when no trace of Jeni could be found in town or the surrounding area. But that confusion gave way to horror when a second woman disappeared.

In 2003, Tim Schuster disappeared after losing his job. Embroiled in a bitter divorce, his friends feared suicide. That is, until police found Tim's body days later, partially dissolved in a bin of hydrochloric acid.

28-year-old Suzette Trouten was just another small town transplant loving life on her own in Kansas City. But when Suzette vanishes, investigators soon discover that she shares ties with a slew of missing women ties fashioned by a sex-crazed serial killer.

Dalia Dippolito was just another trophy wife on the path to Palm Beach high society... until police broke the news that she'd become a trophy widow. Only a surprise confession can reveal the truth about the murder - a deadly game of deception.

As best friends Brian Ognjan and David Tyll arrived in Mio, Michigan for a hunting trip, the two men had no idea they'd end up as prey. The 18-year investigation that followed would reveal a tale of wrong turns, bullying brothers and a wood chipper.

A grisly murder in Rome, Georgia would leave this conservative town reeling. Thad Reynolds, loving husband, father of four and deacon at Hollywood Baptist Church was stabbed 19 times in his office.

In 1994, a single bullet wreaked havoc in Lexington, KY. University of Kentucky football player Trent Diguiro was gunned down by a sniper's bullet. For years the case went unsolved, until a former student came forward, and helped identify the killer.

In 2005, the death of suburban Cleveland resident Rose Marie Essa had doctors and police scratching their heads. An autopsy failed to shed any light on the mystery, but when her physician husband suddenly went missing the shocking truth would be revealed.

The grisly murder of automotive executive Bob Seaman unveiled a dark side of the white collar community of Farmington Hills. The startling confession and groundbreaking trial that followed would divide a family and a city for years to come.

In 2009, a murder mystery would strike the trendy city of Palo Alto when beautiful real estate broker Jennifer Schipsi was found strangled to death and set ablaze in her home.

Somerset native, Sam Catron, was running for his fifth consecutive term as County Sheriff until an assassin's bullet struck him dead at a political rally. Only a confession can reveal the truth - as well as the unlikely trio who conspired to kill him.

In 2000, Michelle Theer was an Air Force wife in the military town of Fayetteville until a fatal shooting made her a widow. The investigation into her husband's death led police to the door of an Army Ranger - taking orders from very unlikely accomplices.

When Tampa bartender Sandee Rozzo was killed, police suspected personal trainer Tracey Humphrey as the culprit. They asked one of Tracey's clients to wear a wire, and discovered he had convinced an unlikely accomplice to pull the trigger.

On March 23, 2006, a respected horticulturalist is found dead in his Key West home. What appears to be an open-and-shut case proves to be anything but when investigators learn the victim was murdered three days prior by a former tenant and possible lover.

In 2002, Erika and BJ Sifrit's vacation in Ocean City, MD ended with them in the back of a squad car arrested for armed robbery. When two dismembered bodies were later unearthed, the connection between the two crimes would reveal a grisly murder.

In 1991, Dana Ireland was found struggling in a secluded jungle in Hilo, but it was too late. Investigators were baffled bywhat looked like a combination rape, and hit-and-run.

In 2009, a murder mystery would strike the trendy city of Palo Alto when beautiful real estate broker Jennifer Schipsi was found strangled to death and set ablaze in her home.

In 2007, Anne Stout was a devoted mother living the Rocky Mountain dream until her husband turned up dead in their Missoula home. Only a few scraps of unlikely evidence would reveal the truth about Bill's murder, as well as his fatal attraction stalker.