The 1994 case of a raped and murdered 16-year-old girl is re-opened when Det. Jeffries gets a call from a prisoner on death-row -- scheduled to be executed in just three days.

The discovery of nine human skulls leads Rush (Kathryn Morris) back to George Marks, the serial killer she was unable to incriminate months earlier, and who walked away a free man. As the detectives reinvestigate his mother's murder from 1972, George is forced to emerge from hiding to face Rush again. This time, their very lives are at stake in their final showdown.

When a young woman, Rosie, wakes up from a coma, Lilly re-opens the fall in which her 6-year-old daughter Toya died. Things get complicated when the mother remembers very little of that night, and Lilly feels especially motivated to find the killer.

The 1975 disappearance of an 8-year-old girl who was never found is reinvestigated after a note written by the girl shortly before she vanished turns up. Their friendship rattled many in the predominantly white neighborhood and the girls quickly became targets of hatred.

The team re-opens the case of the first ever female cadet in a local military school who was murdered in 2005.

When a fisherman finds evidence of a young girl's death washed up on a shore in New Jersey, Lilly re-opens the 1965 case of 4-year-old child who had a seemingly abusive mother.

The team re-investigates the suspected 2007 murder of a bride-to-be who was kidnapped on the day of her engagement party. Lilly and Scotty travel to West Virginia to escort the prime suspect to Philly, and on their way back, they hear his side of the story.

The 1999 drowning death of a military academy's swim coach, which was originally ruled as accidental, is reinvestigated after the homicide division receives a note that suggests it was murder. Back at the office, Valens searches for Elisa after she goes missing.

The 1958 death of an unknown 6-year-old boy found in a field inside a cardboard box is reinvestigated after a small suitcase with the child's picture and his old cowboy hat is left in front of a church. The new probe reveals that the rowdy boy lived at a Catholic-run orphanage and was adopted two days before his suspicious demise.

The headless torso of a woman who disappeared in 1985, on the same day she filed domestic-abuse charges against her husband, is found by hikers in a wildlife preserve. The investigation quickly leads to the grisly discovery of 8 more decapitated bodies, the victims of a serial killer.

When an old truck containing human bones is pulled from the Delaware River, the team re-opens the case of a missing and possibly murdered girl who disappeared unexpectedly in 1932.

Lilly and Valens reopen a presumed homicide from 1979 in which an unidentified victim's blood-drenched shoes, underwear and sheets were found in a trash bag, but no body. The investigation begins when a battered wife accuses her husband of murdering a girl in 1979 and brings in an amateur film from the time that supposedly shows him committing the crime.

The unsolved 1963 murder of a black teenager, whose body was discovered by the then-young Will Jeffries, is reopened.

The investigation into the female cadet's murder continues. As the team finds more and more clues, the killer tries to stop the investigation to remain hidden.

The team re-investigates the 1968 death of a policeman who was shot in his patrol car. The case was then ruled as a drug bust gone bad, but new evidence now reveals the victim may have been romantically involved with his partner.

In the fourth season finale, a hostage situation arises when the entire team is held captive while they're investigating the 2006 killings of a family who had just moved into a new house.

Lilly returns to her last case before joining the Cold Case Squad as she re-investigates the brutal triple homicide of a restaurant owner and his family, murdered in the restaurant bathroom in 2003. Also the other team member have personal reasons to closing the case; Jeffries grew up in the predominantly black neighborhood while Vera was the one assigned to the case when Det. Rush left.

Lilly investigates the case of Daniel Holtz, a college baseball player who was found beaten to death in an alley behind a gay bar in 1964. Daniel's mother comes to Lilly in the hopes that his killer can be brought to justice before she dies. Lilly discovers the maltreatment gay victims received in the 60's, when her investigation discloses that it may have been a policeman's nightstick that made the lethal blows.

Det. Rush investigates the 1991 double murder of married illegal immigrants from Cambodia who were shot to death in their apartment and found by their 6-year old daughter. The now-teenage girl brings the case to Lilly after she discovers a bracelet once owned by her mother is for sale on the internet. The probe reveals that the parents had dark secrets unknown to their daughter.

In 1954, 9-year-old Otis Petrowski last saw his mother in a mental institution. Now over 50 years later, after the death of an elderly woman who had been using Otis' mother's identity, Det. Rush sets out to discover what happened to the boy's real mother.

Det. Stillman asks Lilly to re-open a case he couldn't solve, wherein an 8-year-old boy, Tim Barnes, was murdered in 1980. The prime suspects included a catholic priest, three glue-sniffing teenagers, one elusive suspect, and the boy's own parents.

A drug addict mother, who lost her son in an apartment fire in 2005, comes forth claiming she just saw the same child in the park.

A woman, who was romantically involved with Nick Vera in high school, claims that members of a fraternity might have been involved in her alcoholic sister's death in 1995. The victim's estranged husband and a bar owner are also viewed as potential suspects.

Lilly reopens a 1990 murder case, in which a prep-school girl was found dead in a local swimming hole, after a present-day victim with similar markings is discovered at the same place. The investigation reveals that the victim of the earlier crime was routinely tormented by a trio of classmates who invited her to a sleepover the night she was killed.

Rush and Valens re-open the case of a 25-year-old black woman, who was murdered in 1939, after the woman's granddaughter comes forward with new information. The woman was assumed to be a prostitute murdered by a client, but letters written by the victim indicate that she was afraid of a milkman.

When a note connected to a supposed suicide is found, the team re-opens the 1994 case of a high-school kid who fell from the roof of the school building after having served detention. In 1994 the death was deemed a suicide, but the newly-found note indicates that the victim might have been fearing for his life.

The 1945 case of a murdered newspaper reporter is reopened when new evidence suggests that the woman was thrown in front of a passing train by someone she knew.

Lilly investigates the 1993 death of a mentally challenged teen who was hit by a train, after drawings appear on his grave that indicate foul play might have been involved.

The team re-opens the 1963 case of teenage girl who was then thought to have committed suicide. Now, new evidence leads them to believe the girl might have been murdered for acting and dressing like a boy.

Lilly investigates the 1964 murder of a 17-year-old girl who was sent by her parents to a home for unwed mothers, where she gave birth to a girl. The next day the teen was killed. The case is reopened when the victim's daughter comes forward, having just learned that she was adopted and that her biological mother was slain.

The 1998 death of a terminally ill man who died months before he was expected to is investigated after a nurse confesses to six so-called mercy killings.

The team re-opens the 1999, 2001, and 2003 pipe bombing incidents that killed two and blinded one victim. The serial bomber is still on the loose and ready to strike again as he missed his latest target.

Construction workers discover a skull with bullet hole under the ruins of a disco club burned down in 1978. 22 people died in the fire. Rush and Valens come to the conclusion that the burning of the club was arson, meant to cover up a murder leaving them with not one, but 23 cold cases.

A convicted serial killer will be paroled after 25 years in prison unless Lilly and her team can connect him to the 1977 murder of a young doorman found strangled on a train platform. The killing is eerily similar to other murders committed by the man. Making the case more urgent is the fact that the convicted strangler hints that he will kill again upon release. Elsewhere, Scotty confronts Christina about her past and tries to get her to talk to a New York detective.

The 1999 murder of a homeless woman, whose body is found at the bottom of a river in a station wagon, is investigated.

The team re-opens the case of a woman who allegedly committed suicide in 1962 when the victim's granddaughter comes forth with evidence that the note found on the death scene -- then thought to be the suicide note -- was not written in the victim's handwriting.

Realizing that the missing Vera has finally hit rock bottom, his worried team members hope that a new twist to a 2006 arson case, which he was secretly obsessing about in recent weeks, might supply leads to his whereabouts.

When a body is found in a dumpster, the team re-opens the 1984 case of a murdered teenage boy who wanted to become a dancer against his father's wishes.

On the eve of the 60-year reunion of women who worked in a weapons factory during World War II, Lilly is asked to re-investigate the death of Alice Miller, one of the worker girls. The death was deemed accidental at the time, but her friend pleads to Lilly to look closer into the case.

When the remains of a young black man and a white woman are found under the foundation of a building, Rush and Valens discover that not only did the two go missing in 1969, but that they may have been killed professionally for their work in an underground abortion clinic.

When the body of a newly missing boy is found in a cargo container along with the remains of three other victims who vanished in 1999-2003, the team realizes they're dealing with a serial killer.

When a young girl is contacted by a man claiming to be her father, Det. Rush and her team reopen a 1988 case of a teenaged boy, killed on the same night the girl was born.

After traces of blood linked back to a missing teen are found, the team re-investigates the 2006 case of a boy who disappeared from a high school for deaf children.

Lilly investigates a 1976 case involving a teenage girl who was beaten to death on a tennis court during a party at a plush estate.

A father pushes a registered sex offender off of a building and threatens to kill a different sex offender each day until the cold-case unit solves his son's 1987 rape and murder.

A college professor (Jeffrey Nordling), who lost everything − his career, his family, his reputation − after being suspected of murdering one of his female students (Kaitlin Doubleday) in 1995, offers new information regarding the case that he hopes will clear his name. He believes the student's death is connected to a copycat murder of a prostitute. Rush investigates the woman who was killed and the men in her life in order to discover which one of them killed her.

The team has to cope with their own emotions as they search for the shooter responsible for Jeffries' shooting.

The 1986 murder of a dock worker who moonlighted as a wrestler is investigated. Meanwhile, Valens follows a lead that could result in the capture of his mother's rapist.

The 2005 murder of an Army recruiter who was killed just two days before his scheduled deployment to Iraq is reinvestigated after a soldier comes forward with new evidence.

The 1976 murder of a teen-aged girl is reopened when her father produces a photo of her and a vicious biker gang.

When the remains of a sandhog miner who disappeared in 1947 are found in a subway service tunnel, the team is prompted to re-open the case when they suspect the victim might have been murdered for being a union activist.

The 1974 murder of a private investigator is probed after his body is discovered in the cement foundation of a demolished building. The investigation reveals the victim uncovered damaging information about his last few clients and that he hired a tough associate to provide muscle during his final investigation.

The team suspect a 2004 arson that killed a psychiatrist may have been caused by her former patient.

The 1983 murder of a graffiti artist who died after spray paint was forced down his throat is investigated. Meanwhile, new details emerge about the person who mugged Valen's mother; and Lilly faces additional legal hurdles thrown her way by Moe.

The 1986 murder of a jockey is investigated after his body is discovered in a mass grave for horses. The victim disappeared shortly after losing a race that he had planned to be his finale before retiring.

When the mother of a missing team storms into station. The case of a witness protection member is reopened when his body is identified by the missing teen.

With the team investigating the 1966 shipboard murder of a young woman traveling in steerage on a luxury ocean liner who was believed to have committed suicide by jumping overboard. But new evidence indicates otherwise. Meanwhile, the trial of a military academy official who attempted to harm Lilly begins.

The 1997 murder of a 16-year-old girl high-school cheerleader is investigated after an anonymous confession is discovered in a modern-art exhibit.

The team re-opens the 1999 murder of a Cuban baseball star who fled to the U.S. after being fired from his team.

The team re-opens the 2002 case of a murdered amateur actor when the owner of a local community theater finds a gun hidden inside prop furniture.

The team re-opens the 1995 case of a skateboarding prodigy who lived on the streets.

Rush tries to ignore her father's appeals to give her troublemaker sister another chance after she suddenly resurfaces.

When a new witness steps forward, Lilly and the team are prompted to re-open the 1984 shooting of a respected and beloved ER doctor who had a secret he had been hiding from his family.

The 1944 murder of a female pilot who flew noncombat missions for the U.S. during World War II is investigated. The victim was part of a civilian program that assisted the Army and Air Force. Meanwhile, the man who ran Lilly's car off a road is released from prison on bail.

After determining the serial killer's identity - and some of his likely future targets - the team and the FBI work together to apprehend him while trying to locate and protect the people he's preparing to kill.

After a piece of clothing belonging to a murder victim is found, the team re-opens the 1998 case of a high school girl who had a reputation for being promiscuous.

Rush and FBI agent Ryan Cavanaugh discover their attraction for one another while investigating the 1969 murder of a GI at Woodstock, and Vera helps his married ex-girlfriend, Megan, after sentimental jewelry is stolen from her home.

The 1999 death of a high-school debate champion, which was originally ruled a suicide, is investigated after new evidence suggests he was murdered. The probe reveals the victim received a scholarship at a top private school and died shortly after losing a debate at the competitive campus.

When the victim's younger sister comes looking for her, the team re-opens the 2006 case of a missing Amish girl who was murdered while she was in Philadelphia experiencing the Amish rite of passage called "rumspringa".

When a body is discovered in the trunk of a car, the team re-opens the 1981 case of a missing single mother who used to work at a car dealership.

The 1978 murder of a young man is re-opened after the victim's mother finds a letter suggesting that his death wasn't random.

The 1980 murder of a minor-league hockey player is investigated. The victim was killed on his team's home rink the night the U.S. hockey team defeated the Soviet Union in the Olympic Games.

The team re-opens the 2001 case of a robbed and murdered deli owner when the brother of the man convicted of the crime brings forth new evidence, suggesting the man may have been wrongfully accused.

The team re-investigates the 1953 case of a talented 19-year-old rock'n'roll singer when new evidence comes forth, suggesting he wasn't killed in the place where his body was found.

The 1991 murder of a 14-year-old girl in foster care who was a promising rapper is investigated. The probe reveals the victim lived in a gang-infested neighbourhood and was recently placed, along with her sister, with new foster parents.

After a drug addict brings in an audio tape she found on which a fatal shooting is heard, Lilly reopens a 1973 murder case involving the death of a twenty-one-year-old rookie cop. The young officer was shot three times in the chest while responding to a call at a drug-infested housing project.

Lilly re-opens the 1999 case of a young, healthy woman who nevertheless died of a heart attack. In the late 1990's, she was briefly an Internet millionaire, but due to bad business decisions, her dot.com company eventually went bust.

The team reopens the 1985 case of a wealthy stock broker. At the time it was deemed that Charles Danville was killed when someone attempted to steal his car, but new evidence suggests that he may, in fact, have been murdered.

The team re-investigates the 1958 case of a newlywed real estate developer when new evidence suggests his body might have been moved after he was killed.

Four close high school friends each went their separate ways in 1980. Eight years later, in 1988, one of them was murdered. The homicide team receives a tip about the murder, prompting a re-investigation of the case and an examination of the friends' lives, hopes and dreams after high school.

The team receives new evidence in a 1964 case which was then though to have been a hit-and-run. Now, a threatening letter addressed to the victim prompts Will and Kat to travel to Mississippi to re-investigate the death of a woman who was secretly involved in giving school supplies for black children.

Lilly and Valens travel to Nashville and Knoxville to investigate the 2000 murder of a country-music singer who was gunned down outside of a Philadelphia bar where he and his band had recently played. The unsolved case is reopened when the gun used in the homicide turns up.

A homely 33-year-old woman is gunned down in an alley in 1989 and her unsolved murder is reinvestigated when a tape of the victim, made for a dating service, turns up in a suicide victim's apartment. Apparently, it was what the man was watching when he killed himself. Also, Vera moves into an apartment of his own

The 1983 murder of a Chinese-American teen is reinvestigated. The case was originally handled by Stillman. The probe reveals the victim's girlfriend was killed by Chinese gang members three months earlier at a festival and that the dead man may have been seeking revenge.

When the murder weapon from a 1963 case is unearthed, the team re-opens the murder of a pool hustler who was shot the same day President Kennedy was assassinated.

The team re-opens the 2004 case of a female veteran of the Iraqi War when her prosthetic arm is found in a river. Meanwhile, Scotty visits his older brother in connection with a case that brings up painful memories from their childhood.

When human remains are found in a duck pond, the team reopens the 1967 murder of a brush salesman.

The team re-investigates the 1988 murder of a young TV reporter. Previously unseen news footage suggests she was on the verge of breaking a huge story about the unethical practices of a plastics company.

The 1973 murder of a college-football star's on the eve of a championship game. The unsolved case is reopened when new evidence suggests he was killed earlier than previously assumed and the victim may have been involved with steroids.

Det. Rush re-opens the 1945 case of a baseball player, bludgeoned to death with his own bat.

Lilly and the team attend a colleague's wedding and are persuaded by Jeffries to investigate whether the bride killed her former fiancé two years earlier - just hours after he called off their nuptials.

A 6-month-old girl's 1982 death, originally ruled to be a result of sudden-infant-death syndrome, is investigated when new evidence reveals the baby may have drowned. Also, Lilly learns that Ray is in the hospital after apparently being beaten.

The 1978 death of a teen roller skater who was found in a ravine is reinvestigated when a new witness comes forward.

The team re-opens the 1998 case of a murdered 17-year-old girl when her father is arrested for beating another child.