Acclaimed actor and proud owner of a knighthood, Sir Anthony Hopkins returns to talk to James Lipton about his continually successful career on screen and stage.

Comedian Dave Chappelle discusses his TV and film work, including "Chappelle's Show," "Blue Streak" and "Undercover Brother."

Actor Sean Penn is profiled and interviewed about his career.

The comedic actor discusses his huge successes, his big break and his ever-aspirational outlook on life.

A star-studded audience attends to see the beloved, talented leading man who gives a rare in-depth interview with humor and honesty.

The versatile leading man fills the host and the studio audience in on his unusual entrance to acting and the details of his illustrious film career.

The well-established actor discusses his rise from underdog to premiere Hollywood and stage star.

New York comedian George Carlin fields questions about his long-running standup career, his many dislikes and the nature of life in this frank and revealing interview session.

James Lipton interviews Jessica Chastain, who traces her rise to Hollywood stardom from humble beginnings. She also discusses her theater training at Julliard and her career-altering films, such as "Salomé," "A Most Violent Year" and "Zero Dark Thirty."

James Lipton interviews the band, Bon Jovi. Among other things, they talk about other band names that were discussed.

The constantly popular actor enthusiastically responds to James Liptons questions, including those dealing with his various relationships over the years and his choice to become a Scientologist.

The good-natured family-friendly actor and all-round entertainer shows the audience why he is one of the most well-liked people in Hollywood.

James Lipton interviews the cast of TV's "How I Met Your Mother," including Josh Radnor, Neil Patrick Harris, Alyson Hannigan, Jason Segel and Cobie Smulders.

Actress Hilary Swank becomes the third youngest woman ever to win two Oscars for 'Best Performance by an Actress in a Leading Role.'

James Lipton talks to Charlie Sheen about his various film and TV roles.

Bruce Dern and Laura Dern's individual careers, their personal relationship, and details about their lives and accomplishments.

Matthew McConaughey reflects on his life and career. McConaughey discusses his break into film with 1993's "Dazed and Confused", his decision to play riskier characters, and his preparation for the film "Dallas Buyers Club."

Actor/comedian Billy Crystal makes a second visit to the show to talk with James Lipton about his work in films.

The charismatic character actor discusses his on-screen personas, his writing career, his relationship with fellow actor Matt Damon and all points in-between.

The hugely popular Australian actor discusses his sudden rise to A-list status, his unusual upbringing and his often tempestuous, misunderstood relationship with the press.

James Lipton interviews Jamie Foxx.

Bradley Cooper, star of The Hangover, Limitless and the big-screen adaptation of The A-Team, discusses his life and career.

Comic and actress Tina Fey discusses her comedy roots in Chicago, being a writer for 'Saturday Night Live,' hosting the Golden Globe Awards, and impersonating Sarah Palin.

Actor-director Ron Howard talks about growing up on television as Opie Taylor on "The Andy Griffith Show" and Richie Cunningham on "Happy Days." Also: his approach as a director on films like "Splash," "Night Shift," "Parenthood" and "Apollo 13."

James Lipton set aside a special hour-long broadcast of 'Inside the Actors Studio for the adult castmembers from 'Modern Family.' To keep things interesting -- and a little confusing if you were trying to watch this while multitasking -- Lipton decided to interview both the actors and the characters they play on television.

Tom Hanks returns to the Actors Studio for a second time.

The writer/actor and all-around nice guy discusses how he slowly but surely rose to fame with persistance and support from friends and family, becoming one of the best-paid and most admired performers in the business.

Robert Lipton interviews comedian/actor Chris Rock about his career and background.

The beautiful and talented actress mentions her Californian upbringing, Cuba heritage and incredible success as the leading lady in many blockbuster films, plus her love of rock music.

James Lipton interviews Neil Patrick Harris, who casts light on his multidimensional career, how he reinvented himself after starring in TV's "Doogie Howser, M.D." and how he prepared for his role in Broadway's "Hedwig and the Angry Inch."

It hasn't been the smoothest of careers for the multi-talented entertainer, but here he recounts tales of his best and worst moments with panache.