Sandra and Culebra's big wedding day has arrived, but one guest is missing: Rosa Ruano. After the celebration, the Castillo family launches a risky plan to find her. At the police station, they discover Rosa's phone was last detected deep in a remote forest. Everyone heads into the dark woods except Mario and Dora, who stay in the car. The others find a huge building exactly where the phone signal ends. Inside, they discover hallways covered with the initials 'D.N.A.' and classrooms where young people with powers are trained. Meanwhile, Dora senses something nearby through her abilities…

The Castillo family reunites with old acquaintances at D.N.A. After overcoming an important test that proves the strength of their bond, they must decide whether to stay at the academy or not. Meanwhile, a strange creature watches their every move from the shadows.

Dante reveals a painful secret to Mario, one that once put the academy at risk. Meanwhile, that same threat is taking shape again and stalks both the students and the Castillo family, unaware of the danger surrounding them.

The Castillo family wakes up in the middle of the forest. They must take part in a dangerous test to avoid being expelled and losing their powers, while the possessed continue spreading evil... Who will they infect this time?

The academy is succumbing to the attack of the possessed. Minerva plans a final strike tonight, and her main target is little Dora. Mario will try to escape with the child... Will he manage to save her?

Minerva continues infecting students and instructors, while Sandra and Culebra try to hide and recover Dora to keep her out of the villain's hands. The Castillo family must combine all their powers to ensure Minerva's dark energy does not prevail.