When David Hodges goes missing, the entire CSI team searches for any piece of evidence that can help locate him, clear his name and save the reputation of the entire crime lab.

When the body of a young girl who was killed over 40 years ago is discovered at the bottom of Lake Mead, Max Roby promises her mother, Raquel Williams, that the CSI team will finally find justice for her daughter. Also, Greg Sanders brings his quirky humor as he returns to the crime lab.

As Grissom and Sara close in on who framed Hodges, the CSI team investigates a lock room murder mystery at 30,000 feet, when a cargo plane lands autonomously at McCarran Airport and everyone on board has been killed.

Max puts CSI on lockdown when evidence in a new murder tips Grissom and Sara to a new suspect in the crime lab. Also, Folsom and Allie investigate a series of chilling killings at a dilapidated clown-themed hotel.

The CSI team looks closely at the eccentric world of sideshows when a couple of performers are discovered burned in a pit. Also, Hodges mulls a plea deal as his criminal trial kicks off, while Max, Grissom and Sara search for evidence to exonerate him.

When a young, non-verbal boy is found hiding in a stranger’s garage, the CSI team searches for his missing mother. Also, Max receives a strange letter with symbols in silver ink that Folsom and Allie recognize from prior crime scenes.

When the CSIs are called to investigate human remains found in a convention center owner’s bathtub, Sara and Grissom use the case to get close to attorney Anson Wix’s star forensic expert witness, just days before David Hodges’ trial begins

When the bodies of two Regency Romantic Festival attendees are discovered, the CSI team uncovers a shocking link between their murders and previous cases.

When three masked assailants invade a home and murder an entire family, including a pregnant woman, the CSIs are called to the scene to investigate. Catherine leads the team through the emotional case, which intensifies her own longing to reconnect with her estranged daughter, Lindsey.

The CSI team investigates a murder case that hits close to home for Folsom. When he is forced to sit this investigation out, he does his own digging with help from Trey. Worried Folsom will do something he regrets if he gets his hands on the killer, the team find themselves racing to arrest the suspect first.

A silver ink note threatening Maxine Roby's life is found at the crime lab, sending the entire CSI team to crack who is behind the notes and how they connect to other murder case.

The CSI team investigates when a body is dug up in the luau pit of a Hawaiian-themed hotel. Also, Internal Affairs begins to question Grissom and Sara's return to the crime lab.

The CSI team is called to investigate when the bodies of Frank Sinatra and Joey Bishop impersonators are discovered behind the drywall of a home construction project. Also, Folsom must face the review board about the future of his career.

Catherine’s day off with her granddaughter gets interrupted when a woman wakes up from a four-year coma and remembers details from the night her sister died.

As the CSI team investigates the death of a man visiting Las Vegas for a health and wellness convention, a fiery explosion traps Allie Rajan in the basement of an abandoned hospital.

When a fitness guru is found dead in a gym sauna and his soon to be son-in-law is found dead from an apparent hunting accident, the CSI team investigates to see if these deaths are unrelated tragic accidents or if they're connected.

The CSI team investigates the death of an archaeologist found near the breakthrough discovery of an ancient civilization. Also, Max locates another cryptic note written in familiar silver ink after a mentally distressed woman kills her attacker.

When a mechanic is found murdered in a dark factory, the CSI team investigates whether the perpetrator was human or a humanoid robot with an AI operating system.

The CSI team investigates a bomb that detonated during a masquerade party for wealthy investors at the site of a new casino.

A mysterious bigfoot-like footprint found near a crime scene puzzles the CSI team as they work to uncover who - or what - killed a father and son.

With a new piece of evidence at play, Catherine Willows reopens an investigation from her past that never got solved after a violent attack left her hospitalized. Internal affairs begins questioning Folsom.

The CSI team investigates when a plastinated nervous system is found hanging above a local car dealership. Also, Chavez and Max search for a missing source in their ongoing investigation of the robotics factory.

The CSI team investigates after a group of teens discover a dead woman behind the wheel of an abandoned car in a Nevada ghost town.

The CSI team investigates a case where an ambitious investigative reporter is found dead at a peanut factory. Also, everyone in the crime lab buzzes over who Max will promote to day shift supervisor.