Matt and Abby go through New Dawn's Anomaly on a rescue mission for Connor into the barren, Predator-ruled wastelands of the future, while back in the present, the future apocalypse looms closer as New Dawn spirals out of control. Meanwhile, Jess and Lester face problems of their own when the ARC is invaded by Mutated Future Predators.

Danny and the team face a Medieval-esque incursion when a Dracorex comes through an Anomaly pursued by a Medieval knight, who - believing he has followed the creature into Hell - causes calamity around modern London as the team try to reason the truth to him. Meanwhile, Connor tries to buy Rex back from Jack's greedy friend.

While Sarah and Becker deal with a Megopteran attack at Johnson's old HQ, Danny, Connor and Abby return to the future to stop Helen; the trio soon learn the truth behind Helen's master plan, and are sent on a race through the Anomalies to stop her before she ends humanity at its beginning.

As the team emotionally struggle to recover from the aftermath of Helen's attack, Jenny leads the team to a new Anomaly at an airport; where a Giganotosaurus or "G-Rex" threatens the crew of a Boeing-747, a news crew are attempting to document the incursion for the media, and Danny Quinn gives the reluctant team his unwanted help.

Jenny and the team, with unwanted help from Danny, attempt to stop London from becoming engulfed by a pandemic when they face an incursion of a deadly, fast-spreading fungus from the future that turns its hosts into primal monsters. Meanwhile, Sid the Diictodon has escaped Connor's custody into the ARC and is causing calamity, and Jenny learns the truth about Claudia Brown.

Cutter and the team head to a hospital to deal with an Anomaly and a Diictodon colony wreaking havoc on the hospital's power supply, and also have to help deliver a baby and stop a greedy journalist from getting proof of the creatures. Meanwhile, Helen Cutter and her clone army launch their attack on the ARC, and Helen reveals a secret about the future to Nick.

When Johnson takes Lester's control over the ARC, the team are forced to flee into hiding from Johnson's forces at an abandoned rural military outpost, where they come under attack by a pack of bloodthirsty Terror Birds.

When a young London girl chases her dog through an Anomaly into a harsh, prehistoric desert world, Cutter and Stephen go through on a rescue mission for the girl, but find themselves up against giant sand scorpions. The team's problems only worsen when the Anomaly closes on the trio and leaves them marooned in the hostile desert world.

The team are sent to deal with a Columbian Mammoth rampaging on the M25, and attempt to save a trapped motorist before she frightens the Mammoth into attacking again. Meanwhile, Connor and Abby search for the missing Rex and Caroline, and Stephen reveals his alliance with Helen Cutter. Connor and Cutter spring their trap to find the traitor in the ARC, and Oliver Leek's true colours are exposed and the team race to track him down.

When a Navy submarine in the North Sea discovers a giant underwater Anomaly, Matt, Connor and Abby join the Navy crew aboard, but things go awry when the submarine is pulled through the Anomaly into a prehistoric sea inhabited by giant pliosaurs. The team subsequently attempt to get the submarine back through the Anomaly to their time, while Lester struggles to stop an Admiral from nuking the Anomaly and potentially altering history.

Cutter's new Anomaly predictions lead Jenny, Connor and Abby to a reputedly haunted abandoned house, where they soon learn that the Anomaly incursion dates back fourteen years and the house is inhabited by a deadly Camouflage Beast. The team also have to deal with the antagonistic suspicions of Detective Constable Danny Quinn on their interest in the house.

Eight years after his wife Helen mysteriously disappeared, Nick Cutter and a team of several others investigate reports of a large animal in the Forest of Dean, and discover that mysterious Anomalies in time and space are appearing and allowing prehistoric creatures to cross into the present day.

Helen Cutter directs the team to an Anomaly at a football stadium and escapes through, leaving behind a flock of Dodos. The team soon discover that the Dodos are host to a deadly parasite, and struggle to stop a pandemic when Tom is infected and - convinced that the government are incubating a mind-controlling biological weapon inside him - goes on the run from the team.

Cutter struggles with the arrival of the ARC's new PR guru, Jenny Lewis, who is physically identical to the lost Claudia Brown, yet is temperamentally a completely different person with no idea of her doppelganger; while Connor gets picked up by a beautiful young woman who is everything he is not, but Abby and Rex are both suspicious of her; and Stephen begins seeing Helen again. When an Anomaly releases a yellow, sulphuric mist inhabited by giant, carnivorous worms on a gleaming new high-rise office block, Cutter and Stephen are sent in to deal with the deadly creatures with Jenny, while back at the ARC, Connor and Abby try and find a fog-battling weapon.

The team attempt to track a giant, underground insectoid predator from the future, and there is something about the creature that Matt isn't telling the team. Meanwhile, Philip shows Connor the true purpose behind New Dawn, and Abby becomes more suspicious of Matt and grows closer to discovering his secret, while Lester struggles at the ARC to make a good impression to Ms. Reece of the Cabinet Office for a knighthood.

The team are called in to investigate when a lifeguard is eaten by a Mosasaur at a swimming pool. Cutter discovers that they are dealing with a mobile Anomaly when the Mosasaur and the lifeguard's vomited remains appear at a reservoir and a cellar floods and is invaded by a Hesperornis. The rest of the team also learn that Helen is alive and on the other side of the Anomaly, and so Cutter is forced to go through and confront the woman his wife has become.

When the team send a Raptor at an art museum back through the wrong Anomaly, Matt goes through into Victorian London in pursuit of the Raptor, and there he reunites with Emily and attempts to help her escape her grim fate of incarceration at Bedlam Asylum by her shallow husband. Meanwhile, Abby infiltrates Connor's lab to capture Connor's files on New Dawn for Matt.

When an Anomaly opens at a theatre, a group of mysterious Anomaly travellers come through, followed by fast and deadly Tree Creepers. Meanwhile, Connor helps Philip design a new security system for the ARC, but it goes horribly awry and sends the ARC into lockdown, and time is running out for Connor to free Rex and Philip before the system suffocates them.

When a pest controller is attacked in the London Underground and landed in hospital poisoned with venom, Cutter, Claudia and the team investigate and discover the Underground is infested with giant, Carboniferous spiders. Cutter and the team soon learn that the true culprit is not the spiders, but a giant centipede, and they are sent in a race against time to get the centipede's venom after it poisons Stephen. Meanwhile, Connor gets thrown off the team after telling two of his friends about the Anomalies, and attempts to earn the team's faith back in the fight against the giant centipede. At the same time, Cutter's suspicions that Helen is alive on the other sides of the Anomalies increases.

The team go to investigate a flunctuating Anomaly signal at a seaside village, and Matt and Abby struggle to contain a fast and deadly Labyrinthodont's rampage while Connor tries to uncover the secret behind the fluncuating Anomaly signal. Meanwhile, Emily has been captured by Ethan, and Matt attempts to track and save her before it's too late.

The team investigate when an Anomaly opens in an Ancient Egyptian artefact at the British Museum, and when a Pristichampsus comes through, Cutter, Abby and Jenny are sent into a race after the giant crocodilian through Central London. Meanwhile, Connor and sparky Egyptologist Sarah Page discover that the Anomaly, the artefact and the creature hold an incredible ancient secret.

Matt, Connor and Becker investigate an Anomaly at a secondary school and struggle to save the remaining students from deadly, venomous Therocephalians. Meanwhile, Philip decides to have the ARC's captive creatures including Rex euthanized, prompting Abby to try and smuggle them to safety before it's too late.